Limits...
The enigma of vasculitis.

Ghetie D, Rudinskaya A, Raut R - Int J Rheumatol (2010)

Bottom Line: Based on the clinical and pathological findings, a diagnosis of ANCA-negative granulomatous necrotizing vasculitis involving the small-, medium-, and large-size vessels was made.The patient was treated with prednisone and cyclophosphamide, which was later switched to rituximab.The patient remained asymptomatic under this regimen and stabilization of his kidney function was achieved.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine (Rheumatology and Nephrology & Hypertension), Danbury Hospital, Danbury, CT 06810, Valhalla, NY 10595, USA.

ABSTRACT
We describe the case of an 86-year-old man presenting with clinical symptoms suggestive of Temporal Arteritis. The evolution of the case prompted extensive work-up, including temporal artery and kidney biopsy. Based on the clinical and pathological findings, a diagnosis of ANCA-negative granulomatous necrotizing vasculitis involving the small-, medium-, and large-size vessels was made. The patient was treated with prednisone and cyclophosphamide, which was later switched to rituximab. The patient remained asymptomatic under this regimen and stabilization of his kidney function was achieved.

No MeSH data available.


Related in: MedlinePlus

(a) Crescent formation. (b) Granuloma. (c) Vasculitis in medium-sized renal artery.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC2901610&req=5

fig1: (a) Crescent formation. (b) Granuloma. (c) Vasculitis in medium-sized renal artery.

Mentions: Magnetic Resonance Angiography was negative for renal artery stenosis. In September, 2008, the kidney biopsy was performed, showing acute and chronic granulomatous necrotising vasculitis of medium-sized (renal) arteries and crescent formation. The immunofluorescence report was negative for IgG, IgM, IgA, C3, C1, fibrinogen, albumin, or light chains (Figures 1(a), 1(b), and 1(c)).


The enigma of vasculitis.

Ghetie D, Rudinskaya A, Raut R - Int J Rheumatol (2010)

(a) Crescent formation. (b) Granuloma. (c) Vasculitis in medium-sized renal artery.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2901610&req=5

fig1: (a) Crescent formation. (b) Granuloma. (c) Vasculitis in medium-sized renal artery.
Mentions: Magnetic Resonance Angiography was negative for renal artery stenosis. In September, 2008, the kidney biopsy was performed, showing acute and chronic granulomatous necrotising vasculitis of medium-sized (renal) arteries and crescent formation. The immunofluorescence report was negative for IgG, IgM, IgA, C3, C1, fibrinogen, albumin, or light chains (Figures 1(a), 1(b), and 1(c)).

Bottom Line: Based on the clinical and pathological findings, a diagnosis of ANCA-negative granulomatous necrotizing vasculitis involving the small-, medium-, and large-size vessels was made.The patient was treated with prednisone and cyclophosphamide, which was later switched to rituximab.The patient remained asymptomatic under this regimen and stabilization of his kidney function was achieved.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine (Rheumatology and Nephrology & Hypertension), Danbury Hospital, Danbury, CT 06810, Valhalla, NY 10595, USA.

ABSTRACT
We describe the case of an 86-year-old man presenting with clinical symptoms suggestive of Temporal Arteritis. The evolution of the case prompted extensive work-up, including temporal artery and kidney biopsy. Based on the clinical and pathological findings, a diagnosis of ANCA-negative granulomatous necrotizing vasculitis involving the small-, medium-, and large-size vessels was made. The patient was treated with prednisone and cyclophosphamide, which was later switched to rituximab. The patient remained asymptomatic under this regimen and stabilization of his kidney function was achieved.

No MeSH data available.


Related in: MedlinePlus