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Ulcer over chin in an immunocompromised individual.

Peter D, Thomas M, Mathews M - Am. J. Trop. Med. Hyg. (2010)

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Christian Medical College, Vellore 632004, Tamil Nadu, India. dincypeter@gmail.com

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Superficial ulcer with adherent crusts over the chin. This figure appears in color at www.ajtmh.org.
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Figure 1: Superficial ulcer with adherent crusts over the chin. This figure appears in color at www.ajtmh.org.

Mentions: A 45-year-old human immunodeficiency virus (HIV)-positive male from northeastern India presented with fever and cough as well as a 3-month-old ulcer over the chin. On examination, there was a 5 × 5-cm superficial ulcer with a thick adherent crust over the chin (Figure 1). The individual had three papules with central umbilication over the neck and face. He had anemia (hemoglobin = 7.5 g) and a cluster of differentiation 4 (CD4) count of 89 cells/μL. His chest radiograph and computed tomography (CT) scan of the thorax showed right mid- and lower-zone consolidation. Histopathology of the umbilicated papule and the ulcer showed numerous yeast forms and a few sausage-shaped structures with central septation within the histiocytes (Figure 2). Fungal tissue cultures from skin lesions and bronchoalveolar lavage aspirates showed a greenish yellow, flat, velvety wrinkled colony with surrounding diffusible red pigment (Figure 3). This was diagnostic of Penicillium marneffei infection. Sputum smears and culture were negative for tuberculosis. Direct immunofluorescence detection for Pneumocystis carinii from sputum sample was negative.


Ulcer over chin in an immunocompromised individual.

Peter D, Thomas M, Mathews M - Am. J. Trop. Med. Hyg. (2010)

Superficial ulcer with adherent crusts over the chin. This figure appears in color at www.ajtmh.org.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2877435&req=5

Figure 1: Superficial ulcer with adherent crusts over the chin. This figure appears in color at www.ajtmh.org.
Mentions: A 45-year-old human immunodeficiency virus (HIV)-positive male from northeastern India presented with fever and cough as well as a 3-month-old ulcer over the chin. On examination, there was a 5 × 5-cm superficial ulcer with a thick adherent crust over the chin (Figure 1). The individual had three papules with central umbilication over the neck and face. He had anemia (hemoglobin = 7.5 g) and a cluster of differentiation 4 (CD4) count of 89 cells/μL. His chest radiograph and computed tomography (CT) scan of the thorax showed right mid- and lower-zone consolidation. Histopathology of the umbilicated papule and the ulcer showed numerous yeast forms and a few sausage-shaped structures with central septation within the histiocytes (Figure 2). Fungal tissue cultures from skin lesions and bronchoalveolar lavage aspirates showed a greenish yellow, flat, velvety wrinkled colony with surrounding diffusible red pigment (Figure 3). This was diagnostic of Penicillium marneffei infection. Sputum smears and culture were negative for tuberculosis. Direct immunofluorescence detection for Pneumocystis carinii from sputum sample was negative.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Christian Medical College, Vellore 632004, Tamil Nadu, India. dincypeter@gmail.com

Show MeSH
Related in: MedlinePlus