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Intra-arterial thrombolysis for central retinal artery occlusion: two cases report.

Hwang G, Woo SJ, Jung C, Park KH, Hwang JM, Kwon OK - J. Korean Med. Sci. (2010)

Bottom Line: Central retinal artery occlusion (CRAO) causes severe visual loss in affected eye and vision does not recover in more than 90% of the patients.Of them, one recovered visual acuity to 20/25.To the best of our knowledge, this is the first Korean report of IAT for CRAO.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Chuncheon Sacred Heart Hospital, Hallym University, Chuncheon, Korea.

ABSTRACT
Central retinal artery occlusion (CRAO) causes severe visual loss in affected eye and vision does not recover in more than 90% of the patients. It is believed that it occurs by occlusion of the central retinal artery with small emboli from atherosclerotic plaque of internal cerebral artery. Retina is a part of the brain, thus basically CRAO is corresponding to acute occlusion of intracerebral artery and retinal ischemia is to cerebral stroke. Therefore, intra-arterial thrombolysis (IAT) has been considered as a treatment method in CRAO. Recently, we treated 2 patients diagnosed as CRAO and could achieve complete recanalization on fundus fluorescein angiogram with IAT. Of them, one recovered visual acuity to 20/25. We report our 2 CRAO cases treated with IAT and discuss technical aspects for IAT and management of patient. To the best of our knowledge, this is the first Korean report of IAT for CRAO.

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Related in: MedlinePlus

Fluorescein angiography 1day after intra-arterial thrombolysis in case 2 (A). The retinal perfusion restored to normal and arteriovenous transit time is 12 sec. Fundus photography 2 weeks after thrombolysis (B). There is no more retinal edema suggesting previous ischemia. The vision improved to 20/25.
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Figure 6: Fluorescein angiography 1day after intra-arterial thrombolysis in case 2 (A). The retinal perfusion restored to normal and arteriovenous transit time is 12 sec. Fundus photography 2 weeks after thrombolysis (B). There is no more retinal edema suggesting previous ischemia. The vision improved to 20/25.

Mentions: One day after IAT, his vision improved to 20/40 and fundus fluorescein angiography showed normal retinal perfusion with AV transit time of 12 seconds (Fig. 6A). Two weeks after IAT, his visual acuity improved to 20/25 and there was no more retinal edema (Fig. 6B).


Intra-arterial thrombolysis for central retinal artery occlusion: two cases report.

Hwang G, Woo SJ, Jung C, Park KH, Hwang JM, Kwon OK - J. Korean Med. Sci. (2010)

Fluorescein angiography 1day after intra-arterial thrombolysis in case 2 (A). The retinal perfusion restored to normal and arteriovenous transit time is 12 sec. Fundus photography 2 weeks after thrombolysis (B). There is no more retinal edema suggesting previous ischemia. The vision improved to 20/25.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2877243&req=5

Figure 6: Fluorescein angiography 1day after intra-arterial thrombolysis in case 2 (A). The retinal perfusion restored to normal and arteriovenous transit time is 12 sec. Fundus photography 2 weeks after thrombolysis (B). There is no more retinal edema suggesting previous ischemia. The vision improved to 20/25.
Mentions: One day after IAT, his vision improved to 20/40 and fundus fluorescein angiography showed normal retinal perfusion with AV transit time of 12 seconds (Fig. 6A). Two weeks after IAT, his visual acuity improved to 20/25 and there was no more retinal edema (Fig. 6B).

Bottom Line: Central retinal artery occlusion (CRAO) causes severe visual loss in affected eye and vision does not recover in more than 90% of the patients.Of them, one recovered visual acuity to 20/25.To the best of our knowledge, this is the first Korean report of IAT for CRAO.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Chuncheon Sacred Heart Hospital, Hallym University, Chuncheon, Korea.

ABSTRACT
Central retinal artery occlusion (CRAO) causes severe visual loss in affected eye and vision does not recover in more than 90% of the patients. It is believed that it occurs by occlusion of the central retinal artery with small emboli from atherosclerotic plaque of internal cerebral artery. Retina is a part of the brain, thus basically CRAO is corresponding to acute occlusion of intracerebral artery and retinal ischemia is to cerebral stroke. Therefore, intra-arterial thrombolysis (IAT) has been considered as a treatment method in CRAO. Recently, we treated 2 patients diagnosed as CRAO and could achieve complete recanalization on fundus fluorescein angiogram with IAT. Of them, one recovered visual acuity to 20/25. We report our 2 CRAO cases treated with IAT and discuss technical aspects for IAT and management of patient. To the best of our knowledge, this is the first Korean report of IAT for CRAO.

Show MeSH
Related in: MedlinePlus