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Cluster of serogroup W135 meningococci, southeastern Florida, 2008-2009.

Doyle TJ, Mejia-Echeverry A, Fiorella P, Leguen F, Livengood J, Kay R, Hopkins R - Emerging Infect. Dis. (2010)

Bottom Line: Recently, 14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections.All isolates tested had matching or near-matching pulsed-field gel electrophoresis patterns and belonged to the multilocus sequence type 11 clonal complex.The epidemiologic investigation suggested recent endemic transmission of this clonal complex in southeastern Florida.

View Article: PubMed Central - PubMed

Affiliation: Department of Health, Miami, Florida, USA. tdoyle@cdc.gov

ABSTRACT
Recently, 14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections. All isolates tested had matching or near-matching pulsed-field gel electrophoresis patterns and belonged to the multilocus sequence type 11 clonal complex. The epidemiologic investigation suggested recent endemic transmission of this clonal complex in southeastern Florida.

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Related in: MedlinePlus

Confirmed meningococcal disease cases, by month of onset, Florida, USA, May 2008–April 2009.
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Related In: Results  -  Collection


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Figure 2: Confirmed meningococcal disease cases, by month of onset, Florida, USA, May 2008–April 2009.

Mentions: Illness onset for the 14 W135 patients in this cluster is shown in relation to onset for all 38 meningococcal disease patients with other serogroups identified in Florida during the same 12-month period (Figure 2). Demographic and clinical factors were also compared between these serogroup W135 and non-W135 patients (Table 2). As a group, serogroup W135 patients were older, were more likely to be Hispanic and to reside in or be visiting the southeastern 3-county region, were more likely to have bacteremia, and had higher mortality rates than non-W135 serogroup patients. However, other than Hispanic ethnicity and residence in the southeastern region, none of these differences were significant.


Cluster of serogroup W135 meningococci, southeastern Florida, 2008-2009.

Doyle TJ, Mejia-Echeverry A, Fiorella P, Leguen F, Livengood J, Kay R, Hopkins R - Emerging Infect. Dis. (2010)

Confirmed meningococcal disease cases, by month of onset, Florida, USA, May 2008–April 2009.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2874373&req=5

Figure 2: Confirmed meningococcal disease cases, by month of onset, Florida, USA, May 2008–April 2009.
Mentions: Illness onset for the 14 W135 patients in this cluster is shown in relation to onset for all 38 meningococcal disease patients with other serogroups identified in Florida during the same 12-month period (Figure 2). Demographic and clinical factors were also compared between these serogroup W135 and non-W135 patients (Table 2). As a group, serogroup W135 patients were older, were more likely to be Hispanic and to reside in or be visiting the southeastern 3-county region, were more likely to have bacteremia, and had higher mortality rates than non-W135 serogroup patients. However, other than Hispanic ethnicity and residence in the southeastern region, none of these differences were significant.

Bottom Line: Recently, 14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections.All isolates tested had matching or near-matching pulsed-field gel electrophoresis patterns and belonged to the multilocus sequence type 11 clonal complex.The epidemiologic investigation suggested recent endemic transmission of this clonal complex in southeastern Florida.

View Article: PubMed Central - PubMed

Affiliation: Department of Health, Miami, Florida, USA. tdoyle@cdc.gov

ABSTRACT
Recently, 14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections. All isolates tested had matching or near-matching pulsed-field gel electrophoresis patterns and belonged to the multilocus sequence type 11 clonal complex. The epidemiologic investigation suggested recent endemic transmission of this clonal complex in southeastern Florida.

Show MeSH
Related in: MedlinePlus