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Cluster of serogroup W135 meningococci, southeastern Florida, 2008-2009.

Doyle TJ, Mejia-Echeverry A, Fiorella P, Leguen F, Livengood J, Kay R, Hopkins R - Emerging Infect. Dis. (2010)

Bottom Line: Recently, 14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections.All isolates tested had matching or near-matching pulsed-field gel electrophoresis patterns and belonged to the multilocus sequence type 11 clonal complex.The epidemiologic investigation suggested recent endemic transmission of this clonal complex in southeastern Florida.

View Article: PubMed Central - PubMed

Affiliation: Department of Health, Miami, Florida, USA. tdoyle@cdc.gov

ABSTRACT
Recently, 14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections. All isolates tested had matching or near-matching pulsed-field gel electrophoresis patterns and belonged to the multilocus sequence type 11 clonal complex. The epidemiologic investigation suggested recent endemic transmission of this clonal complex in southeastern Florida.

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Related in: MedlinePlus

Pulsed-field gel electrophoresis (PFGE) patterns for 14 related and 4 unrelated isolates of Neisseria meningitidis serogroup W135, Florida, USA.
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Related In: Results  -  Collection


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Figure 1: Pulsed-field gel electrophoresis (PFGE) patterns for 14 related and 4 unrelated isolates of Neisseria meningitidis serogroup W135, Florida, USA.

Mentions: From December 2008 through April 2009, we observed an increase of invasive meningococcal disease caused by serogroup W135 in southeastern Florida totaling 13 patients, of whom 9 had indistinguishable PFGE patterns (Figure 1). Isolates from the 4 other case-patients had PFGE patterns differing by 1 (pattern II), 2 (pattern III), and 5 bands (pattern IV), making them >94% related to the dominant pattern. A retrospective review of all 5 W135 isolates in Florida from January 2007 through November 2008 identified 1 additional isolate matching the dominant pattern from a resident of southeastern Florida with illness onset in May 2008. The 4 other isolates from 2007–2008 had PFGE patterns <80% related (Figure 1) and occurred before May 2008 in residents of central and northern Florida.


Cluster of serogroup W135 meningococci, southeastern Florida, 2008-2009.

Doyle TJ, Mejia-Echeverry A, Fiorella P, Leguen F, Livengood J, Kay R, Hopkins R - Emerging Infect. Dis. (2010)

Pulsed-field gel electrophoresis (PFGE) patterns for 14 related and 4 unrelated isolates of Neisseria meningitidis serogroup W135, Florida, USA.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2874373&req=5

Figure 1: Pulsed-field gel electrophoresis (PFGE) patterns for 14 related and 4 unrelated isolates of Neisseria meningitidis serogroup W135, Florida, USA.
Mentions: From December 2008 through April 2009, we observed an increase of invasive meningococcal disease caused by serogroup W135 in southeastern Florida totaling 13 patients, of whom 9 had indistinguishable PFGE patterns (Figure 1). Isolates from the 4 other case-patients had PFGE patterns differing by 1 (pattern II), 2 (pattern III), and 5 bands (pattern IV), making them >94% related to the dominant pattern. A retrospective review of all 5 W135 isolates in Florida from January 2007 through November 2008 identified 1 additional isolate matching the dominant pattern from a resident of southeastern Florida with illness onset in May 2008. The 4 other isolates from 2007–2008 had PFGE patterns <80% related (Figure 1) and occurred before May 2008 in residents of central and northern Florida.

Bottom Line: Recently, 14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections.All isolates tested had matching or near-matching pulsed-field gel electrophoresis patterns and belonged to the multilocus sequence type 11 clonal complex.The epidemiologic investigation suggested recent endemic transmission of this clonal complex in southeastern Florida.

View Article: PubMed Central - PubMed

Affiliation: Department of Health, Miami, Florida, USA. tdoyle@cdc.gov

ABSTRACT
Recently, 14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections. All isolates tested had matching or near-matching pulsed-field gel electrophoresis patterns and belonged to the multilocus sequence type 11 clonal complex. The epidemiologic investigation suggested recent endemic transmission of this clonal complex in southeastern Florida.

Show MeSH
Related in: MedlinePlus