Limits...
Problem formulation in the environmental risk assessment for genetically modified plants.

Wolt JD, Keese P, Raybould A, Fitzpatrick JW, Burachik M, Gray A, Olin SS, Schiemann J, Sears M, Wu F - Transgenic Res. (2009)

Bottom Line: A properly executed PF assures the relevance of ERA outcomes for decision-making.Adopting a harmonized approach to problem formulation should bring about greater uniformity in the ERA process for GM plants among regulatory regimes globally.This paper is the product of an international expert group convened by the International Life Sciences Institute (ILSI) Research Foundation.

View Article: PubMed Central - PubMed

Affiliation: Biosafety Institute for Genetically Modified Agricultural Products, Iowa State University, Ames, IA, USA. jdwolt@iastate.edu

ABSTRACT
Problem formulation is the first step in environmental risk assessment (ERA) where policy goals, scope, assessment endpoints, and methodology are distilled to an explicitly stated problem and approach for analysis. The consistency and utility of ERAs for genetically modified (GM) plants can be improved through rigorous problem formulation (PF), producing an analysis plan that describes relevant exposure scenarios and the potential consequences of these scenarios. A properly executed PF assures the relevance of ERA outcomes for decision-making. Adopting a harmonized approach to problem formulation should bring about greater uniformity in the ERA process for GM plants among regulatory regimes globally. This paper is the product of an international expert group convened by the International Life Sciences Institute (ILSI) Research Foundation.

Show MeSH

Related in: MedlinePlus

Example of a conceptual model for ERA (Sears et al. 2001)
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC2865628&req=5

Fig2: Example of a conceptual model for ERA (Sears et al. 2001)

Mentions: Diagrammatic conceptual models are particularly powerful as shown in Fig. 2 (Sears et al. 2001). In this example, the various elements contributing to exposure and effect are outlined in a way that describes how data elements and their synthesis are means of evaluating the risks of Bt maize on monarch butterfly larvae populations.Fig. 2


Problem formulation in the environmental risk assessment for genetically modified plants.

Wolt JD, Keese P, Raybould A, Fitzpatrick JW, Burachik M, Gray A, Olin SS, Schiemann J, Sears M, Wu F - Transgenic Res. (2009)

Example of a conceptual model for ERA (Sears et al. 2001)
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2865628&req=5

Fig2: Example of a conceptual model for ERA (Sears et al. 2001)
Mentions: Diagrammatic conceptual models are particularly powerful as shown in Fig. 2 (Sears et al. 2001). In this example, the various elements contributing to exposure and effect are outlined in a way that describes how data elements and their synthesis are means of evaluating the risks of Bt maize on monarch butterfly larvae populations.Fig. 2

Bottom Line: A properly executed PF assures the relevance of ERA outcomes for decision-making.Adopting a harmonized approach to problem formulation should bring about greater uniformity in the ERA process for GM plants among regulatory regimes globally.This paper is the product of an international expert group convened by the International Life Sciences Institute (ILSI) Research Foundation.

View Article: PubMed Central - PubMed

Affiliation: Biosafety Institute for Genetically Modified Agricultural Products, Iowa State University, Ames, IA, USA. jdwolt@iastate.edu

ABSTRACT
Problem formulation is the first step in environmental risk assessment (ERA) where policy goals, scope, assessment endpoints, and methodology are distilled to an explicitly stated problem and approach for analysis. The consistency and utility of ERAs for genetically modified (GM) plants can be improved through rigorous problem formulation (PF), producing an analysis plan that describes relevant exposure scenarios and the potential consequences of these scenarios. A properly executed PF assures the relevance of ERA outcomes for decision-making. Adopting a harmonized approach to problem formulation should bring about greater uniformity in the ERA process for GM plants among regulatory regimes globally. This paper is the product of an international expert group convened by the International Life Sciences Institute (ILSI) Research Foundation.

Show MeSH
Related in: MedlinePlus