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Deposition of silver nanoparticles on titanium surface for antibacterial effect.

Juan L, Zhimin Z, Anchun M, Lei L, Jingchao Z - Int J Nanomedicine (2010)

Bottom Line: The diameter of these nanoparticles ranged from ten to several hundred nm.EDS analyses revealed that there was 4.26% of Ag present on the surface.These data suggest that silver nanoparticle-modified titanium is a promising material with an antibacterial property that may be used as an implantable biomaterial.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, PR China.

ABSTRACT
Microbial colonization on implanted devices and biofilm formation is a recurrent complication in implant surgery and may result in loss of implants. The aim of this study was to deposit silver nanoparticles on a titanium surface to obtain antibacterial properties. In the present study, we prepared a silver nanoparticle-modified titanium (Ti-nAg) surface using silanization method. The morphology and chemical components of the Ti-nAg surface were characterized by scanning electron microscopy (SEM) equipped with energy-dispersive spectroscopy (EDS). Two species of bacteria, Staphylococcus aureus and Escherichia coli, were utilized to test the antibacterial effect of the Ti-nAg treated surface. The SEM examination revealed that a small quantity of silver nanoparticles was sparsely deposited on the titanium surface. The diameter of these nanoparticles ranged from ten to several hundred nm. EDS analyses revealed that there was 4.26% of Ag present on the surface. After a 24-hour incubation, 94% of Staphylococcus aureus and over 95% of Escherichia coli had been killed on the Ti-nAg surface, and the SEM examination of anti-adhesive efficacy test showed that there were less bacteria attached to Ti-nAg surface than to a control surface of untreated Titanium. These data suggest that silver nanoparticle-modified titanium is a promising material with an antibacterial property that may be used as an implantable biomaterial.

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SEM images of the Ti-polished (a and c) and Ti-nAg (b and d) surfaces after incubation of Staphylococcus aureus (a and b) and Escherichia coli (c and d).Notes: Magnification ×2000, working distance 8000 μm.Abbreviation: SEM, scanning electron microscopy.
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f6-ijn-5-261: SEM images of the Ti-polished (a and c) and Ti-nAg (b and d) surfaces after incubation of Staphylococcus aureus (a and b) and Escherichia coli (c and d).Notes: Magnification ×2000, working distance 8000 μm.Abbreviation: SEM, scanning electron microscopy.

Mentions: The SEM examination of anti-adhesive test showed that there were much less bacteria adherent to Ti-nAg surface than to the control titanium surface (Figure 6). This was due to the direct contact inhibition and the anti-adhesive properties of the Ti-nAg surface. Therefore it is suggested that the Ti-nAg surface reduces the risk of bacterial colonization.


Deposition of silver nanoparticles on titanium surface for antibacterial effect.

Juan L, Zhimin Z, Anchun M, Lei L, Jingchao Z - Int J Nanomedicine (2010)

SEM images of the Ti-polished (a and c) and Ti-nAg (b and d) surfaces after incubation of Staphylococcus aureus (a and b) and Escherichia coli (c and d).Notes: Magnification ×2000, working distance 8000 μm.Abbreviation: SEM, scanning electron microscopy.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2865021&req=5

f6-ijn-5-261: SEM images of the Ti-polished (a and c) and Ti-nAg (b and d) surfaces after incubation of Staphylococcus aureus (a and b) and Escherichia coli (c and d).Notes: Magnification ×2000, working distance 8000 μm.Abbreviation: SEM, scanning electron microscopy.
Mentions: The SEM examination of anti-adhesive test showed that there were much less bacteria adherent to Ti-nAg surface than to the control titanium surface (Figure 6). This was due to the direct contact inhibition and the anti-adhesive properties of the Ti-nAg surface. Therefore it is suggested that the Ti-nAg surface reduces the risk of bacterial colonization.

Bottom Line: The diameter of these nanoparticles ranged from ten to several hundred nm.EDS analyses revealed that there was 4.26% of Ag present on the surface.These data suggest that silver nanoparticle-modified titanium is a promising material with an antibacterial property that may be used as an implantable biomaterial.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, PR China.

ABSTRACT
Microbial colonization on implanted devices and biofilm formation is a recurrent complication in implant surgery and may result in loss of implants. The aim of this study was to deposit silver nanoparticles on a titanium surface to obtain antibacterial properties. In the present study, we prepared a silver nanoparticle-modified titanium (Ti-nAg) surface using silanization method. The morphology and chemical components of the Ti-nAg surface were characterized by scanning electron microscopy (SEM) equipped with energy-dispersive spectroscopy (EDS). Two species of bacteria, Staphylococcus aureus and Escherichia coli, were utilized to test the antibacterial effect of the Ti-nAg treated surface. The SEM examination revealed that a small quantity of silver nanoparticles was sparsely deposited on the titanium surface. The diameter of these nanoparticles ranged from ten to several hundred nm. EDS analyses revealed that there was 4.26% of Ag present on the surface. After a 24-hour incubation, 94% of Staphylococcus aureus and over 95% of Escherichia coli had been killed on the Ti-nAg surface, and the SEM examination of anti-adhesive efficacy test showed that there were less bacteria attached to Ti-nAg surface than to a control surface of untreated Titanium. These data suggest that silver nanoparticle-modified titanium is a promising material with an antibacterial property that may be used as an implantable biomaterial.

Show MeSH
Related in: MedlinePlus