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Bone mass of overweight affluent Indian youth and its sex-specific association with body composition.

Amarendra Reddy G, Kulkarni B, Shatrugna V, Thilak Ravindra Reddy P, Nagalla B, Ajeya Kumar P, Usha Rani K - Arch Osteoporos (2009)

Bottom Line: However, BMD at lumbar spine, forearm, and whole body were not significantly different in the two BMI groups.Lean body mass was an important determinant of BMDs in men, but both lean and fat mass were important for BMDs in women.Body composition parameters may have sex-specific associations with BMD.

View Article: PubMed Central - PubMed

Affiliation: Clinical Division, National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania P.O., Hyderabad, 500 007 India.

ABSTRACT
SUMMARY: The study assessed whether overweight is associated with better bone densities in healthy youth. It was observed that overweight individuals had better BMDs at the hip but not at other sites after controlling for the bone area. Lean body mass was an important determinant of BMDs in men, but both lean and fat mass were important for BMDs in women. INTRODUCTION: The study assessed the relationship of overweight and obesity to the bone mass in young men and women consuming adequate calcium. METHODS: Bone and body composition parameters were measured using dual energy X-ray absorptiometry in overweight men (n = 74) and women (n = 77) in the age group of 20-35 years and compared with controls having normal body mass index (BMI). Biochemical parameters of bone metabolism were also assessed. RESULTS: After adjustment for whole body bone area, bone mineral densities (BMDs) at femoral neck and hip were significantly higher in overweight individuals when compared with controls. However, BMD at lumbar spine, forearm, and whole body were not significantly different in the two BMI groups. Overweight women had lower vitamin D and higher parathormone levels than controls. Regression analyses indicated that height was an important determinant of BMD at most of the skeletal sites in both men and women. Lean body mass was an important determinant of BMDs in men, but both lean and fat mass were important for BMDs in women. CONCLUSION: Overweight may be associated with better BMDs at the hip but not at other sites after controlling for the bone area. Body composition parameters may have sex-specific associations with BMD.

No MeSH data available.


Related in: MedlinePlus

Bone mineral densities at different skeletal sites in the two BMI groups of women. There were significant differences in the BMD of the two BMI groups of women at femoral neck (p < 0.001), hip (p < 0.001), lumbar spine (p = 0.018), and forearm (p = 0.001)
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Fig2: Bone mineral densities at different skeletal sites in the two BMI groups of women. There were significant differences in the BMD of the two BMI groups of women at femoral neck (p < 0.001), hip (p < 0.001), lumbar spine (p = 0.018), and forearm (p = 0.001)

Mentions: The BMC and BMD at femoral neck, hip, and lumbar spine were significantly higher in the HBMI group when compared to the NBMI group among both men and women (Figs. 1 and 2).The mean (SE) whole body bone area (WB-BA) was significantly higher among the high BMI group when compared to normal BMI group among both men and women (2,150 (20) vs. 2.086 (24) cm2 in men and 1,809 (15) vs. 1,733 (16) cm2 in women, P = 0.02 and 0.01 for men and women respectively) indicating larger skeletal frame in those having high BMI. As the areal BMD is known to increase with increase in bone area [26], it was thought that the higher BMD values observed in the individuals with high BMI may be because of their higher bone area. To eliminate the effect of different bone areas in the two BMI groups, we compared the BMC and BMD values in the two BMI groups after controlling for the WB-BA. The adjusted values are, therefore, presented in Table 3.Fig. 1


Bone mass of overweight affluent Indian youth and its sex-specific association with body composition.

Amarendra Reddy G, Kulkarni B, Shatrugna V, Thilak Ravindra Reddy P, Nagalla B, Ajeya Kumar P, Usha Rani K - Arch Osteoporos (2009)

Bone mineral densities at different skeletal sites in the two BMI groups of women. There were significant differences in the BMD of the two BMI groups of women at femoral neck (p < 0.001), hip (p < 0.001), lumbar spine (p = 0.018), and forearm (p = 0.001)
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Related In: Results  -  Collection

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Fig2: Bone mineral densities at different skeletal sites in the two BMI groups of women. There were significant differences in the BMD of the two BMI groups of women at femoral neck (p < 0.001), hip (p < 0.001), lumbar spine (p = 0.018), and forearm (p = 0.001)
Mentions: The BMC and BMD at femoral neck, hip, and lumbar spine were significantly higher in the HBMI group when compared to the NBMI group among both men and women (Figs. 1 and 2).The mean (SE) whole body bone area (WB-BA) was significantly higher among the high BMI group when compared to normal BMI group among both men and women (2,150 (20) vs. 2.086 (24) cm2 in men and 1,809 (15) vs. 1,733 (16) cm2 in women, P = 0.02 and 0.01 for men and women respectively) indicating larger skeletal frame in those having high BMI. As the areal BMD is known to increase with increase in bone area [26], it was thought that the higher BMD values observed in the individuals with high BMI may be because of their higher bone area. To eliminate the effect of different bone areas in the two BMI groups, we compared the BMC and BMD values in the two BMI groups after controlling for the WB-BA. The adjusted values are, therefore, presented in Table 3.Fig. 1

Bottom Line: However, BMD at lumbar spine, forearm, and whole body were not significantly different in the two BMI groups.Lean body mass was an important determinant of BMDs in men, but both lean and fat mass were important for BMDs in women.Body composition parameters may have sex-specific associations with BMD.

View Article: PubMed Central - PubMed

Affiliation: Clinical Division, National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania P.O., Hyderabad, 500 007 India.

ABSTRACT
SUMMARY: The study assessed whether overweight is associated with better bone densities in healthy youth. It was observed that overweight individuals had better BMDs at the hip but not at other sites after controlling for the bone area. Lean body mass was an important determinant of BMDs in men, but both lean and fat mass were important for BMDs in women. INTRODUCTION: The study assessed the relationship of overweight and obesity to the bone mass in young men and women consuming adequate calcium. METHODS: Bone and body composition parameters were measured using dual energy X-ray absorptiometry in overweight men (n = 74) and women (n = 77) in the age group of 20-35 years and compared with controls having normal body mass index (BMI). Biochemical parameters of bone metabolism were also assessed. RESULTS: After adjustment for whole body bone area, bone mineral densities (BMDs) at femoral neck and hip were significantly higher in overweight individuals when compared with controls. However, BMD at lumbar spine, forearm, and whole body were not significantly different in the two BMI groups. Overweight women had lower vitamin D and higher parathormone levels than controls. Regression analyses indicated that height was an important determinant of BMD at most of the skeletal sites in both men and women. Lean body mass was an important determinant of BMDs in men, but both lean and fat mass were important for BMDs in women. CONCLUSION: Overweight may be associated with better BMDs at the hip but not at other sites after controlling for the bone area. Body composition parameters may have sex-specific associations with BMD.

No MeSH data available.


Related in: MedlinePlus