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Oral candidiasis in Chikungunya viral fever: a case report.

Kumar JC, Vivek Y, Sudhindra P, Dhananjaya B, Kumar AT, Guru K, Kumar A, Hegde MB - Cases J (2010)

Bottom Line: A 32 year old Indian male patient presented with chief complaints of a high fever, erythema on ear, severe polyarthritic joint pains & swelling, non pitting pedal oedema, facial puffiness and itching for past four days.Oral cavity inspection revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth which was later microbiologically confirmed as Candidiasis.He tested negative for HIV and had leucopenia with severe CD4 T-lymphocytopenia.

View Article: PubMed Central - HTML - PubMed

Affiliation: KS Hegde Medical Academy, Nithyananda nagar, Deralakatte, Mangalore 575001, India. jairaj81in@yahoo.co.in.

ABSTRACT
A 32 year old Indian male patient presented with chief complaints of a high fever, erythema on ear, severe polyarthritic joint pains & swelling, non pitting pedal oedema, facial puffiness and itching for past four days. He had no significant past medical and drug history and was serologically confirmed to have Chikungunya. Oral cavity inspection revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth which was later microbiologically confirmed as Candidiasis. He tested negative for HIV and had leucopenia with severe CD4 T-lymphocytopenia. This is the first report of an opportunistic infection with CD4 T-lymphocytopaenia in Chikungunya fever.

No MeSH data available.


Related in: MedlinePlus

Oral cavity inspection on review revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth, later microbiologically confirmed as Candidiasis.
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Figure 1: Oral cavity inspection on review revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth, later microbiologically confirmed as Candidiasis.

Mentions: Oral cavity inspection on review revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth, later microbiologically confirmed as Candidiasis [figure 1]. After noting the Candidiasis plaques, the patient's blood sample was again sent for CD4 lymphocyte count analysis and HIV conclusive diagnostic tests using ELISA and western blot. The results showed HIV negative and CD4 lymphocytes of 260 cells/micro liter. In addition, we also noted oral Candidiasis in several other Chikungunya patients during this epidemic. Hence, we postulate that the Chikungunya viral fever induced transient immune depression which could lead to the entry of potential Opportunistic Infections such as Candidiasis.


Oral candidiasis in Chikungunya viral fever: a case report.

Kumar JC, Vivek Y, Sudhindra P, Dhananjaya B, Kumar AT, Guru K, Kumar A, Hegde MB - Cases J (2010)

Oral cavity inspection on review revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth, later microbiologically confirmed as Candidiasis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2823716&req=5

Figure 1: Oral cavity inspection on review revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth, later microbiologically confirmed as Candidiasis.
Mentions: Oral cavity inspection on review revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth, later microbiologically confirmed as Candidiasis [figure 1]. After noting the Candidiasis plaques, the patient's blood sample was again sent for CD4 lymphocyte count analysis and HIV conclusive diagnostic tests using ELISA and western blot. The results showed HIV negative and CD4 lymphocytes of 260 cells/micro liter. In addition, we also noted oral Candidiasis in several other Chikungunya patients during this epidemic. Hence, we postulate that the Chikungunya viral fever induced transient immune depression which could lead to the entry of potential Opportunistic Infections such as Candidiasis.

Bottom Line: A 32 year old Indian male patient presented with chief complaints of a high fever, erythema on ear, severe polyarthritic joint pains & swelling, non pitting pedal oedema, facial puffiness and itching for past four days.Oral cavity inspection revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth which was later microbiologically confirmed as Candidiasis.He tested negative for HIV and had leucopenia with severe CD4 T-lymphocytopenia.

View Article: PubMed Central - HTML - PubMed

Affiliation: KS Hegde Medical Academy, Nithyananda nagar, Deralakatte, Mangalore 575001, India. jairaj81in@yahoo.co.in.

ABSTRACT
A 32 year old Indian male patient presented with chief complaints of a high fever, erythema on ear, severe polyarthritic joint pains & swelling, non pitting pedal oedema, facial puffiness and itching for past four days. He had no significant past medical and drug history and was serologically confirmed to have Chikungunya. Oral cavity inspection revealed whitish non erythematous pseudo membranous plaques on the hard palate, buccal surface of cheek and the floor of the mouth which was later microbiologically confirmed as Candidiasis. He tested negative for HIV and had leucopenia with severe CD4 T-lymphocytopenia. This is the first report of an opportunistic infection with CD4 T-lymphocytopaenia in Chikungunya fever.

No MeSH data available.


Related in: MedlinePlus