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Littoral cell angioma (LCA) associated with liver cirrhosis.

Kim HG, Park IS, Lee JI, Jeong S, Lee JW, Kwon KS, Lee DH, Kim PS, Kim HG, Shin YW, Kim YS, Ahn IS, Lee KY - Yonsei Med. J. (2005)

Bottom Line: A littoral cell angioma (LCA) is a rare benign vascular tumor of the spleen.A thrombocytopenia was found on hematological evaluation.The histological and immunohistochemical features of the splenic specimens were consistent with a LCA.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Gastroenterology Division, Inha University Hospital, Inha University, 7-206, 3-ga, Shinheung-dong, Jung-gu, Incheon 400-103, Korea.

ABSTRACT
A littoral cell angioma (LCA) is a rare benign vascular tumor of the spleen. A 60-year-old man, with multiple nodules in imaging study and liver cirrhosis graded as Child-Pugh classification class A, was transferred for splenomegaly. A thrombocytopenia was found on hematological evaluation. Because there was no evidence of hematological and visceral malignancy, a splenectomy was performed for a definitive diagnosis. The histological and immunohistochemical features of the splenic specimens were consistent with a LCA. After the splenectomy, the thrombocytopenia recovered to the normal platelet count. There has been no previous report of a LCA combined with liver cirrhosis. Herein, the first case of a LCA in Korea, diagnosed and treated by a splenectomy, is reported.

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A. T2-weighted abdominal magnetic resonance image shows multiple splenic nodules with high signal intensity. B. T1-weighted abdominal magnetic resonance image shows multiple splenic nodules with iso to low-signal intensity.
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Figure 2: A. T2-weighted abdominal magnetic resonance image shows multiple splenic nodules with high signal intensity. B. T1-weighted abdominal magnetic resonance image shows multiple splenic nodules with iso to low-signal intensity.

Mentions: The abdominal ultrasonography showed splenomegaly (13.0 cm) with a 5.7 mm sized small cyst and liver cirrhosis, with coarse, heterogeneous echogenicity and a nodular surface. The abdominal computed tomography (CT) scan showed splenomegaly with the multiple hypodense nodules of different sizes and liver cirrhosis featuring a nodular surface, heterogeneous density and mild atrophy of the left lobe (Fig. 1). There was no visible lymphadenopathy on the CT scan. The splenomegaly, with multiple nodules and liver cirrhosis, were found on abdominal MRI (Fig. 2).


Littoral cell angioma (LCA) associated with liver cirrhosis.

Kim HG, Park IS, Lee JI, Jeong S, Lee JW, Kwon KS, Lee DH, Kim PS, Kim HG, Shin YW, Kim YS, Ahn IS, Lee KY - Yonsei Med. J. (2005)

A. T2-weighted abdominal magnetic resonance image shows multiple splenic nodules with high signal intensity. B. T1-weighted abdominal magnetic resonance image shows multiple splenic nodules with iso to low-signal intensity.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2823050&req=5

Figure 2: A. T2-weighted abdominal magnetic resonance image shows multiple splenic nodules with high signal intensity. B. T1-weighted abdominal magnetic resonance image shows multiple splenic nodules with iso to low-signal intensity.
Mentions: The abdominal ultrasonography showed splenomegaly (13.0 cm) with a 5.7 mm sized small cyst and liver cirrhosis, with coarse, heterogeneous echogenicity and a nodular surface. The abdominal computed tomography (CT) scan showed splenomegaly with the multiple hypodense nodules of different sizes and liver cirrhosis featuring a nodular surface, heterogeneous density and mild atrophy of the left lobe (Fig. 1). There was no visible lymphadenopathy on the CT scan. The splenomegaly, with multiple nodules and liver cirrhosis, were found on abdominal MRI (Fig. 2).

Bottom Line: A littoral cell angioma (LCA) is a rare benign vascular tumor of the spleen.A thrombocytopenia was found on hematological evaluation.The histological and immunohistochemical features of the splenic specimens were consistent with a LCA.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Gastroenterology Division, Inha University Hospital, Inha University, 7-206, 3-ga, Shinheung-dong, Jung-gu, Incheon 400-103, Korea.

ABSTRACT
A littoral cell angioma (LCA) is a rare benign vascular tumor of the spleen. A 60-year-old man, with multiple nodules in imaging study and liver cirrhosis graded as Child-Pugh classification class A, was transferred for splenomegaly. A thrombocytopenia was found on hematological evaluation. Because there was no evidence of hematological and visceral malignancy, a splenectomy was performed for a definitive diagnosis. The histological and immunohistochemical features of the splenic specimens were consistent with a LCA. After the splenectomy, the thrombocytopenia recovered to the normal platelet count. There has been no previous report of a LCA combined with liver cirrhosis. Herein, the first case of a LCA in Korea, diagnosed and treated by a splenectomy, is reported.

Show MeSH
Related in: MedlinePlus