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Pulmonary mucormycosis mimicking as pulmonary tuberculosis: a case report.

Garg R, Marak RS, Verma SK, Singh J - Lung India (2008)

Bottom Line: It occurs predminantly in an immunodeficient host most common risk factor being diabetes mellitus.The lesions are localized in the lungs or the mediastinum.We are reporting a case of 70 years old male, having cough, haemoptysis, fever and chest pain.

View Article: PubMed Central - PubMed

Affiliation: Assistant Professor Department of Pulmonary Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow.

ABSTRACT
Pulmonary Mucormycosis is an uncommon disease caused by fungi of class Zygomycetes. It occurs predminantly in an immunodeficient host most common risk factor being diabetes mellitus. The lesions are localized in the lungs or the mediastinum. We are reporting a case of 70 years old male, having cough, haemoptysis, fever and chest pain. He was on antituberculosis treatment (RHEZ) for last 10 days and was later found to have Pulmonary Mucormycosis on further evaluation.

No MeSH data available.


Related in: MedlinePlus

GMS (Gomori's Methanamine Silver staining) from Fine Needle Aspiration sample showing broad randomly branched and aseptate hyphae of Mucormycosis.
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Figure 0002: GMS (Gomori's Methanamine Silver staining) from Fine Needle Aspiration sample showing broad randomly branched and aseptate hyphae of Mucormycosis.

Mentions: He was put on antibiotics (Co-amoxiclav and clindamycin) for 2 weeks without any clinical and radiological response. Patient refused for bronchoscopy. Transthoracic needle aspiration from left cavitary lesion was done, and sent for AFB smear, malignant cells and fungal smear examination. Aspirate was negative for AFB and malignant cells. Direct KOH mount and GMS staining of the aspirate showed a few broad aseptate thin walled fungal hyphae with right angle branching, characteristic of Zygomycetes1 (Fig. 2). Fungal culture of the aspirate inoculated on to SDA media yielded white cottony colonies with no reverse pigmentation in 7 days. Lacto phenol cotton blue mount from the culture showed broad hyaline, thin walled aseptate fungal hyphae with right angle branching, typical of Zygomycetes fungus. He was started on multiple subcutaneous insulin regimens for glycemic control and intravenous Amphotericin-B (50mg/day) after which he showed improvement, clinically as well as radiologically. He is on regular follow up with no further complaints.


Pulmonary mucormycosis mimicking as pulmonary tuberculosis: a case report.

Garg R, Marak RS, Verma SK, Singh J - Lung India (2008)

GMS (Gomori's Methanamine Silver staining) from Fine Needle Aspiration sample showing broad randomly branched and aseptate hyphae of Mucormycosis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2822332&req=5

Figure 0002: GMS (Gomori's Methanamine Silver staining) from Fine Needle Aspiration sample showing broad randomly branched and aseptate hyphae of Mucormycosis.
Mentions: He was put on antibiotics (Co-amoxiclav and clindamycin) for 2 weeks without any clinical and radiological response. Patient refused for bronchoscopy. Transthoracic needle aspiration from left cavitary lesion was done, and sent for AFB smear, malignant cells and fungal smear examination. Aspirate was negative for AFB and malignant cells. Direct KOH mount and GMS staining of the aspirate showed a few broad aseptate thin walled fungal hyphae with right angle branching, characteristic of Zygomycetes1 (Fig. 2). Fungal culture of the aspirate inoculated on to SDA media yielded white cottony colonies with no reverse pigmentation in 7 days. Lacto phenol cotton blue mount from the culture showed broad hyaline, thin walled aseptate fungal hyphae with right angle branching, typical of Zygomycetes fungus. He was started on multiple subcutaneous insulin regimens for glycemic control and intravenous Amphotericin-B (50mg/day) after which he showed improvement, clinically as well as radiologically. He is on regular follow up with no further complaints.

Bottom Line: It occurs predminantly in an immunodeficient host most common risk factor being diabetes mellitus.The lesions are localized in the lungs or the mediastinum.We are reporting a case of 70 years old male, having cough, haemoptysis, fever and chest pain.

View Article: PubMed Central - PubMed

Affiliation: Assistant Professor Department of Pulmonary Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow.

ABSTRACT
Pulmonary Mucormycosis is an uncommon disease caused by fungi of class Zygomycetes. It occurs predminantly in an immunodeficient host most common risk factor being diabetes mellitus. The lesions are localized in the lungs or the mediastinum. We are reporting a case of 70 years old male, having cough, haemoptysis, fever and chest pain. He was on antituberculosis treatment (RHEZ) for last 10 days and was later found to have Pulmonary Mucormycosis on further evaluation.

No MeSH data available.


Related in: MedlinePlus