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Serum ethanol levels after alcohol sclerotherapy of arteriovenous malformations.

Lee JJ, Do YS, Kim JA - J. Korean Med. Sci. (2004)

Bottom Line: Blood ethanol level, amounts of given alcohol, location of lesions, methods of flow control, and Doppler resistive index (RI) were analyzed.The average amount of injected alcohol was 0.89 mL/kg in the patients with the serum levels above the legal intoxication level (>80 mg/dL).It is recommended to keep an eye on the possibility of intoxication when using the amounts of alcohol exceeding 0.89 mL/kg in the sclerotherapy of AVMs.

View Article: PubMed Central - PubMed

Affiliation: Department of Anesthesiology and Pain Medicine, Sungkyunkwan University School of Medicine, Samsung Seoul Hospital, 50 Ilwon-dong, Kangnam-gu, Seoul 135-710, Korea.

ABSTRACT
We analyzed the effects of several factors on the serum ethanol levels after alcohol sclerotherapy in the arteriovenous malformations (AVMs) retrospectively. Blood ethanol level, amounts of given alcohol, location of lesions, methods of flow control, and Doppler resistive index (RI) were analyzed. The results of linear regression analysis showed that the amount of alcohol administered was the predictor of serum ethanol level (r2=0.75, p<0.001). The average amount of injected alcohol was 0.89 mL/kg in the patients with the serum levels above the legal intoxication level (>80 mg/dL). Location of the lesions was not related with the serum ethanol level (p=0.643), and other variables such as forms of flow control and RI were not related to the serum ethanol level after controlling for injected amounts of alcohol (analysis of covariance). It is recommended to keep an eye on the possibility of intoxication when using the amounts of alcohol exceeding 0.89 mL/kg in the sclerotherapy of AVMs.

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Related in: MedlinePlus

Relationship between amounts of injected ethanol and serum ethanol levels in all 90 patients (y=101.4x-0.76, r2=0.75).
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Figure 1: Relationship between amounts of injected ethanol and serum ethanol levels in all 90 patients (y=101.4x-0.76, r2=0.75).

Mentions: The relationship between plasma ethanol level and amount of injected ethanol was significant. The model of simple regression yielded a linear regression with a significant Spearman's correlation coefficient (r2=0.75, p<0.001, Fig. 1).


Serum ethanol levels after alcohol sclerotherapy of arteriovenous malformations.

Lee JJ, Do YS, Kim JA - J. Korean Med. Sci. (2004)

Relationship between amounts of injected ethanol and serum ethanol levels in all 90 patients (y=101.4x-0.76, r2=0.75).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2822263&req=5

Figure 1: Relationship between amounts of injected ethanol and serum ethanol levels in all 90 patients (y=101.4x-0.76, r2=0.75).
Mentions: The relationship between plasma ethanol level and amount of injected ethanol was significant. The model of simple regression yielded a linear regression with a significant Spearman's correlation coefficient (r2=0.75, p<0.001, Fig. 1).

Bottom Line: Blood ethanol level, amounts of given alcohol, location of lesions, methods of flow control, and Doppler resistive index (RI) were analyzed.The average amount of injected alcohol was 0.89 mL/kg in the patients with the serum levels above the legal intoxication level (>80 mg/dL).It is recommended to keep an eye on the possibility of intoxication when using the amounts of alcohol exceeding 0.89 mL/kg in the sclerotherapy of AVMs.

View Article: PubMed Central - PubMed

Affiliation: Department of Anesthesiology and Pain Medicine, Sungkyunkwan University School of Medicine, Samsung Seoul Hospital, 50 Ilwon-dong, Kangnam-gu, Seoul 135-710, Korea.

ABSTRACT
We analyzed the effects of several factors on the serum ethanol levels after alcohol sclerotherapy in the arteriovenous malformations (AVMs) retrospectively. Blood ethanol level, amounts of given alcohol, location of lesions, methods of flow control, and Doppler resistive index (RI) were analyzed. The results of linear regression analysis showed that the amount of alcohol administered was the predictor of serum ethanol level (r2=0.75, p<0.001). The average amount of injected alcohol was 0.89 mL/kg in the patients with the serum levels above the legal intoxication level (>80 mg/dL). Location of the lesions was not related with the serum ethanol level (p=0.643), and other variables such as forms of flow control and RI were not related to the serum ethanol level after controlling for injected amounts of alcohol (analysis of covariance). It is recommended to keep an eye on the possibility of intoxication when using the amounts of alcohol exceeding 0.89 mL/kg in the sclerotherapy of AVMs.

Show MeSH
Related in: MedlinePlus