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The relationship between disc degeneration and morphologic changes in the intervertebral foramen of the cervical spine: a cadaveric MRI and CT study.

Sohn HM, You JW, Lee JY - J. Korean Med. Sci. (2004)

Bottom Line: The segmental angles were decreased more in advanced degenerated discs.There was a correlation between nerve root compression and decreased foraminal width and area (p<0.005).This information and critical dimensions of the intervertebral foramen for nerve root compression should help in the diagnosis of foraminal stenosis of the cervical spine in patients presenting with cervical spondylosis and radiculopathy.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedic Surgery, Chosun University Hospital, Gwangju, Korea. jwyou@chosun.ac.kr

ABSTRACT
A cadaveric study was performed to investigate the relationship between disc degeneration and morphological changes in the intervertebral foramen of cervical spine, including the effect on the nerve root. Seven fresh frozen human cadavers were dissected from C1 to T1, preserving the ligaments, capsules, intervertebral disc and the neural structures. The specimens were scanned with MRI and then scanned through CT scan in the upright position. Direct mid-sagittal and 45 degree oblique images were obtained to measure the dimension of the intervertebral disc height, foraminal height, width, area and segmental angles. Disc degeneration was inversely correlated with disc height. There was a significant correlation between disc degeneration and foraminal width (p<0.005) and foraminal area (p< 0.05), but not with foraminal height. Disc height was correlated with foraminal width but not with height. The segmental angles were decreased more in advanced degenerated discs. There was a correlation between nerve root compression and decreased foraminal width and area (p<0.005). This information and critical dimensions of the intervertebral foramen for nerve root compression should help in the diagnosis of foraminal stenosis of the cervical spine in patients presenting with cervical spondylosis and radiculopathy.

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Related in: MedlinePlus

Diagram showing the sagittal parameters of measurement. 1. Anterior disc height, 2. Midpoint disc height, 3. Posterior disc height, 4. Posterior bulging of disc, 5. Distance of spur, 6. Segmental angle of body, 7. Vertebral body translation, 8. Foraminal height, 9. Middle foraminal width, 10. Foraminal area, 11. Nerve root condition.
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Figure 3: Diagram showing the sagittal parameters of measurement. 1. Anterior disc height, 2. Midpoint disc height, 3. Posterior disc height, 4. Posterior bulging of disc, 5. Distance of spur, 6. Segmental angle of body, 7. Vertebral body translation, 8. Foraminal height, 9. Middle foraminal width, 10. Foraminal area, 11. Nerve root condition.

Mentions: A total of 8 parameters were measured on the midsagittal and oblique plane CT images, including the disc height (anterior, mid-point, and posterior), foraminal height, foraminal middle width, posterior bulging of the intervertebral disc, distances of the posterior osteophyte from the endplate of the vertebral body, segmental angulation of vertebral body, vertebral body translation and the cross sectional area of the foramen (Fig. 3). The cross sectional area of the foramen, which was outlined by the facet joint, the 2 pedicles, the vertebral body and the posterior border of the disc was computed using National Institutes of Health image program software (Scion image, Scion Corporation, Frederick, MD, U.S.A.). All of the measurements were made independently by 3 investigators. The measurements were repeated twice and took the mean value to reduce the errors of measurements. The differences between the measurements of the groups at the different levels were analyzed by ANOVA, and regression analysis was performed to determine any correlation between each parameters.


The relationship between disc degeneration and morphologic changes in the intervertebral foramen of the cervical spine: a cadaveric MRI and CT study.

Sohn HM, You JW, Lee JY - J. Korean Med. Sci. (2004)

Diagram showing the sagittal parameters of measurement. 1. Anterior disc height, 2. Midpoint disc height, 3. Posterior disc height, 4. Posterior bulging of disc, 5. Distance of spur, 6. Segmental angle of body, 7. Vertebral body translation, 8. Foraminal height, 9. Middle foraminal width, 10. Foraminal area, 11. Nerve root condition.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2822244&req=5

Figure 3: Diagram showing the sagittal parameters of measurement. 1. Anterior disc height, 2. Midpoint disc height, 3. Posterior disc height, 4. Posterior bulging of disc, 5. Distance of spur, 6. Segmental angle of body, 7. Vertebral body translation, 8. Foraminal height, 9. Middle foraminal width, 10. Foraminal area, 11. Nerve root condition.
Mentions: A total of 8 parameters were measured on the midsagittal and oblique plane CT images, including the disc height (anterior, mid-point, and posterior), foraminal height, foraminal middle width, posterior bulging of the intervertebral disc, distances of the posterior osteophyte from the endplate of the vertebral body, segmental angulation of vertebral body, vertebral body translation and the cross sectional area of the foramen (Fig. 3). The cross sectional area of the foramen, which was outlined by the facet joint, the 2 pedicles, the vertebral body and the posterior border of the disc was computed using National Institutes of Health image program software (Scion image, Scion Corporation, Frederick, MD, U.S.A.). All of the measurements were made independently by 3 investigators. The measurements were repeated twice and took the mean value to reduce the errors of measurements. The differences between the measurements of the groups at the different levels were analyzed by ANOVA, and regression analysis was performed to determine any correlation between each parameters.

Bottom Line: The segmental angles were decreased more in advanced degenerated discs.There was a correlation between nerve root compression and decreased foraminal width and area (p<0.005).This information and critical dimensions of the intervertebral foramen for nerve root compression should help in the diagnosis of foraminal stenosis of the cervical spine in patients presenting with cervical spondylosis and radiculopathy.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedic Surgery, Chosun University Hospital, Gwangju, Korea. jwyou@chosun.ac.kr

ABSTRACT
A cadaveric study was performed to investigate the relationship between disc degeneration and morphological changes in the intervertebral foramen of cervical spine, including the effect on the nerve root. Seven fresh frozen human cadavers were dissected from C1 to T1, preserving the ligaments, capsules, intervertebral disc and the neural structures. The specimens were scanned with MRI and then scanned through CT scan in the upright position. Direct mid-sagittal and 45 degree oblique images were obtained to measure the dimension of the intervertebral disc height, foraminal height, width, area and segmental angles. Disc degeneration was inversely correlated with disc height. There was a significant correlation between disc degeneration and foraminal width (p<0.005) and foraminal area (p< 0.05), but not with foraminal height. Disc height was correlated with foraminal width but not with height. The segmental angles were decreased more in advanced degenerated discs. There was a correlation between nerve root compression and decreased foraminal width and area (p<0.005). This information and critical dimensions of the intervertebral foramen for nerve root compression should help in the diagnosis of foraminal stenosis of the cervical spine in patients presenting with cervical spondylosis and radiculopathy.

Show MeSH
Related in: MedlinePlus