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Juxta-articular myxoma of the knee in a 5-year-old boy: a case report and review of the literature (2009: 12b).

Körver RJ, Theunissen PH, van de Kreeke WT, van der Linde MJ, Heyligers IC - Eur Radiol (2010)

Bottom Line: The peak incidence is between the 3rd and 5th decades of life.In this report we describe an extremely rare case of JAM in the knee of a 5-year-old child.The clinical presentation, radiological features and histopathologic findings are described, and the relevant literature is reviewed.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedic Surgery, Atrium Medical Center Parkstad Heerlen, Henri Dunantstraat 5, 6419, PC, Heerlen, The Netherlands. rob.korver@zonnet.nl

ABSTRACT
Juxta-articular myxoma (JAM) is a relatively rare variant of myxoma that occurs in the vicinity of large joints. It is composed of fibroblast-like cells that produce an excessive amount of glycosaminoglycans rich in hyaluronic acid. The peak incidence is between the 3rd and 5th decades of life. In this report we describe an extremely rare case of JAM in the knee of a 5-year-old child. The clinical presentation, radiological features and histopathologic findings are described, and the relevant literature is reviewed.

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Related in: MedlinePlus

a, b, c MR images show a mass near the medial metaphysis of the right knee, measuring 4.0 × 3.0 × 2.0 cm, which displaces the distal part of the vastus medialis muscle to medio-cranial. a Coronal T1-weighted MR image shows a mass, hypointense to muscle and with a low signal intensity core. b On T2-weighted MR images, the mass is hyperintense to muscle and isointense to fat. The multiple septa are clearly visible. c Intraveneous admission of gadolinium shows markedly increased signal intensity of the thickened wall and septa without enhancement of the core
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Fig1: a, b, c MR images show a mass near the medial metaphysis of the right knee, measuring 4.0 × 3.0 × 2.0 cm, which displaces the distal part of the vastus medialis muscle to medio-cranial. a Coronal T1-weighted MR image shows a mass, hypointense to muscle and with a low signal intensity core. b On T2-weighted MR images, the mass is hyperintense to muscle and isointense to fat. The multiple septa are clearly visible. c Intraveneous admission of gadolinium shows markedly increased signal intensity of the thickened wall and septa without enhancement of the core

Mentions: Magnetic resonance imaging (MRI) of the affected knee showed a well-defined, heterogeneous and extra-articular mass measuring 4.0 × 3.0 × 2.0 cm near the medio-distal femoral metaphysis (Fig. 1). The lesion did not infiltrate adjacent bone, muscles, vessels or nerves. The distal part of the vastus medialis muscle was displaced to medio-cranial. On T1-weighted images, the lesion was hypointense to muscle with a low signal intensity core, a thickened wall and multiple septa that both had a slightly higher signal intensity. Using gadolinium-enhanced MR the thickened wall and septa became markedly enhanced without enhancement of the core. T2-weighted sequences of the lesion showed an evident high signal intensity, being hyperintense to fat, as well as multiple septa. No further abnormalities could be seen on the MR images.Fig. 1


Juxta-articular myxoma of the knee in a 5-year-old boy: a case report and review of the literature (2009: 12b).

Körver RJ, Theunissen PH, van de Kreeke WT, van der Linde MJ, Heyligers IC - Eur Radiol (2010)

a, b, c MR images show a mass near the medial metaphysis of the right knee, measuring 4.0 × 3.0 × 2.0 cm, which displaces the distal part of the vastus medialis muscle to medio-cranial. a Coronal T1-weighted MR image shows a mass, hypointense to muscle and with a low signal intensity core. b On T2-weighted MR images, the mass is hyperintense to muscle and isointense to fat. The multiple septa are clearly visible. c Intraveneous admission of gadolinium shows markedly increased signal intensity of the thickened wall and septa without enhancement of the core
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2822226&req=5

Fig1: a, b, c MR images show a mass near the medial metaphysis of the right knee, measuring 4.0 × 3.0 × 2.0 cm, which displaces the distal part of the vastus medialis muscle to medio-cranial. a Coronal T1-weighted MR image shows a mass, hypointense to muscle and with a low signal intensity core. b On T2-weighted MR images, the mass is hyperintense to muscle and isointense to fat. The multiple septa are clearly visible. c Intraveneous admission of gadolinium shows markedly increased signal intensity of the thickened wall and septa without enhancement of the core
Mentions: Magnetic resonance imaging (MRI) of the affected knee showed a well-defined, heterogeneous and extra-articular mass measuring 4.0 × 3.0 × 2.0 cm near the medio-distal femoral metaphysis (Fig. 1). The lesion did not infiltrate adjacent bone, muscles, vessels or nerves. The distal part of the vastus medialis muscle was displaced to medio-cranial. On T1-weighted images, the lesion was hypointense to muscle with a low signal intensity core, a thickened wall and multiple septa that both had a slightly higher signal intensity. Using gadolinium-enhanced MR the thickened wall and septa became markedly enhanced without enhancement of the core. T2-weighted sequences of the lesion showed an evident high signal intensity, being hyperintense to fat, as well as multiple septa. No further abnormalities could be seen on the MR images.Fig. 1

Bottom Line: The peak incidence is between the 3rd and 5th decades of life.In this report we describe an extremely rare case of JAM in the knee of a 5-year-old child.The clinical presentation, radiological features and histopathologic findings are described, and the relevant literature is reviewed.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedic Surgery, Atrium Medical Center Parkstad Heerlen, Henri Dunantstraat 5, 6419, PC, Heerlen, The Netherlands. rob.korver@zonnet.nl

ABSTRACT
Juxta-articular myxoma (JAM) is a relatively rare variant of myxoma that occurs in the vicinity of large joints. It is composed of fibroblast-like cells that produce an excessive amount of glycosaminoglycans rich in hyaluronic acid. The peak incidence is between the 3rd and 5th decades of life. In this report we describe an extremely rare case of JAM in the knee of a 5-year-old child. The clinical presentation, radiological features and histopathologic findings are described, and the relevant literature is reviewed.

Show MeSH
Related in: MedlinePlus