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Nodal staging.

Ganeshalingam S, Koh DM - Cancer Imaging (2009)

Bottom Line: Lymph node metastases are a poor prognostic indicator in many tumours and therefore accurate identification during staging is important prior to commencing treatment.The presence of lymph node metastases can significantly alter patient management and therefore accurate diagnosis of the presence and extent of nodal disease can help optimise patient management.The clinical role of positron emission tomography-CT imaging for nodal staging is discussed and emerging imaging techniques that may further improve nodal staging accuracy are surveyed.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical Radiology, Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK. skandadasganesh@yahoo.co.uk

ABSTRACT
Lymph node metastases are a poor prognostic indicator in many tumours and therefore accurate identification during staging is important prior to commencing treatment. The presence of lymph node metastases can significantly alter patient management and therefore accurate diagnosis of the presence and extent of nodal disease can help optimise patient management. In this review, the radiologic features that aid in the differentiation of malignant and benign lymph nodes are discussed. The keys to successful interpretation on cross-sectional computed tomography (CT) and magnetic resonance imaging of nodal metastases are highlighted. The clinical role of positron emission tomography-CT imaging for nodal staging is discussed and emerging imaging techniques that may further improve nodal staging accuracy are surveyed.

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(A) T1-weighted axial image of the pelvis demonstrating multiple enlarged inguinal lymph nodes (arrow) which are low signal in a 61-year-old woman with cervical cancer. (B) Fat-saturated post-contrast images of the pelvis demonstrating multiple enlarged inguinal lymph nodes (arrow) which are of high signal in a 61-year-old woman with cervical cancer.
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Figure 5: (A) T1-weighted axial image of the pelvis demonstrating multiple enlarged inguinal lymph nodes (arrow) which are low signal in a 61-year-old woman with cervical cancer. (B) Fat-saturated post-contrast images of the pelvis demonstrating multiple enlarged inguinal lymph nodes (arrow) which are of high signal in a 61-year-old woman with cervical cancer.

Mentions: Nodal signal characteristics on MR imaging. Generally it is not possible to distinguish between malignant (Fig. 5a,b) and benign nodes on MR imaging based on nodal signal characteristics alone as normal nodes return a range of signal intensities on T1- and T2-weighted imaging.


Nodal staging.

Ganeshalingam S, Koh DM - Cancer Imaging (2009)

(A) T1-weighted axial image of the pelvis demonstrating multiple enlarged inguinal lymph nodes (arrow) which are low signal in a 61-year-old woman with cervical cancer. (B) Fat-saturated post-contrast images of the pelvis demonstrating multiple enlarged inguinal lymph nodes (arrow) which are of high signal in a 61-year-old woman with cervical cancer.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2821588&req=5

Figure 5: (A) T1-weighted axial image of the pelvis demonstrating multiple enlarged inguinal lymph nodes (arrow) which are low signal in a 61-year-old woman with cervical cancer. (B) Fat-saturated post-contrast images of the pelvis demonstrating multiple enlarged inguinal lymph nodes (arrow) which are of high signal in a 61-year-old woman with cervical cancer.
Mentions: Nodal signal characteristics on MR imaging. Generally it is not possible to distinguish between malignant (Fig. 5a,b) and benign nodes on MR imaging based on nodal signal characteristics alone as normal nodes return a range of signal intensities on T1- and T2-weighted imaging.

Bottom Line: Lymph node metastases are a poor prognostic indicator in many tumours and therefore accurate identification during staging is important prior to commencing treatment.The presence of lymph node metastases can significantly alter patient management and therefore accurate diagnosis of the presence and extent of nodal disease can help optimise patient management.The clinical role of positron emission tomography-CT imaging for nodal staging is discussed and emerging imaging techniques that may further improve nodal staging accuracy are surveyed.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical Radiology, Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK. skandadasganesh@yahoo.co.uk

ABSTRACT
Lymph node metastases are a poor prognostic indicator in many tumours and therefore accurate identification during staging is important prior to commencing treatment. The presence of lymph node metastases can significantly alter patient management and therefore accurate diagnosis of the presence and extent of nodal disease can help optimise patient management. In this review, the radiologic features that aid in the differentiation of malignant and benign lymph nodes are discussed. The keys to successful interpretation on cross-sectional computed tomography (CT) and magnetic resonance imaging of nodal metastases are highlighted. The clinical role of positron emission tomography-CT imaging for nodal staging is discussed and emerging imaging techniques that may further improve nodal staging accuracy are surveyed.

Show MeSH
Related in: MedlinePlus