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Nodal staging.

Ganeshalingam S, Koh DM - Cancer Imaging (2009)

Bottom Line: Lymph node metastases are a poor prognostic indicator in many tumours and therefore accurate identification during staging is important prior to commencing treatment.The presence of lymph node metastases can significantly alter patient management and therefore accurate diagnosis of the presence and extent of nodal disease can help optimise patient management.The clinical role of positron emission tomography-CT imaging for nodal staging is discussed and emerging imaging techniques that may further improve nodal staging accuracy are surveyed.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical Radiology, Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK. skandadasganesh@yahoo.co.uk

ABSTRACT
Lymph node metastases are a poor prognostic indicator in many tumours and therefore accurate identification during staging is important prior to commencing treatment. The presence of lymph node metastases can significantly alter patient management and therefore accurate diagnosis of the presence and extent of nodal disease can help optimise patient management. In this review, the radiologic features that aid in the differentiation of malignant and benign lymph nodes are discussed. The keys to successful interpretation on cross-sectional computed tomography (CT) and magnetic resonance imaging of nodal metastases are highlighted. The clinical role of positron emission tomography-CT imaging for nodal staging is discussed and emerging imaging techniques that may further improve nodal staging accuracy are surveyed.

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Related in: MedlinePlus

An axial contrast-enhanced CT demonstrating a large left common iliac cystic lymph node (arrow) in a 34-year-old man with a germ cell tumour.
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Figure 4: An axial contrast-enhanced CT demonstrating a large left common iliac cystic lymph node (arrow) in a 34-year-old man with a germ cell tumour.

Mentions: Low density cystic appearance. Metastatic nodes arising from non-seminomatous germ cell tumour of the testes frequently demonstrate a central low density on CT (Fig. 4)[19]. A non-enlarged cystic lymph node in this tumour group is likely to be involved. They are typically high signal on T2-weighted images. Solid to cystic change within a lymph node after chemotherapy in patients with non-seminomatomous germ cell tumour represents mature differentiation of teratoma. Low attenuation nodes are not pathognomic of malignant infiltration as they are found in tuberculosis and fungal infections.


Nodal staging.

Ganeshalingam S, Koh DM - Cancer Imaging (2009)

An axial contrast-enhanced CT demonstrating a large left common iliac cystic lymph node (arrow) in a 34-year-old man with a germ cell tumour.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2821588&req=5

Figure 4: An axial contrast-enhanced CT demonstrating a large left common iliac cystic lymph node (arrow) in a 34-year-old man with a germ cell tumour.
Mentions: Low density cystic appearance. Metastatic nodes arising from non-seminomatous germ cell tumour of the testes frequently demonstrate a central low density on CT (Fig. 4)[19]. A non-enlarged cystic lymph node in this tumour group is likely to be involved. They are typically high signal on T2-weighted images. Solid to cystic change within a lymph node after chemotherapy in patients with non-seminomatomous germ cell tumour represents mature differentiation of teratoma. Low attenuation nodes are not pathognomic of malignant infiltration as they are found in tuberculosis and fungal infections.

Bottom Line: Lymph node metastases are a poor prognostic indicator in many tumours and therefore accurate identification during staging is important prior to commencing treatment.The presence of lymph node metastases can significantly alter patient management and therefore accurate diagnosis of the presence and extent of nodal disease can help optimise patient management.The clinical role of positron emission tomography-CT imaging for nodal staging is discussed and emerging imaging techniques that may further improve nodal staging accuracy are surveyed.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical Radiology, Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK. skandadasganesh@yahoo.co.uk

ABSTRACT
Lymph node metastases are a poor prognostic indicator in many tumours and therefore accurate identification during staging is important prior to commencing treatment. The presence of lymph node metastases can significantly alter patient management and therefore accurate diagnosis of the presence and extent of nodal disease can help optimise patient management. In this review, the radiologic features that aid in the differentiation of malignant and benign lymph nodes are discussed. The keys to successful interpretation on cross-sectional computed tomography (CT) and magnetic resonance imaging of nodal metastases are highlighted. The clinical role of positron emission tomography-CT imaging for nodal staging is discussed and emerging imaging techniques that may further improve nodal staging accuracy are surveyed.

Show MeSH
Related in: MedlinePlus