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Riedel's thyroiditis masquerading as anaplastic thyroid carcinoma: a case report.

Shahi N, Abdelhamid MF, Jindall M, Awad RW - J Med Case Rep (2010)

Bottom Line: We discuss the presentation, investigation and management of this very rare condition.This was successfully treated with very high dose steroids, with no relapse in the symptoms.In addition, our case demonstrates that this condition should be treated with very high dose steroids to prevent relapse.

View Article: PubMed Central - HTML - PubMed

Affiliation: Warwick Hospital, Lakin house, Lakin Road, CV34 5BW, UK.

ABSTRACT

Introduction: Riedel's thyroiditis is a rare thyroid disease characterized by dense fibrous tissues that replace the thyroid gland and invade the adjacent structures that can mimic thyroid malignancy. We discuss the presentation, investigation and management of this very rare condition.

Case presentation: We present a case of a 59-year-old African-Caribbean man who presented with a rapidly growing hard neck mass, a hoarse voice, dysphagia and breathing difficulty that clinically suggested thyroid malignancy. Biopsy, however, revealed dense fibrous tissues suggestive of Riedel's thyroiditis. This was successfully treated with very high dose steroids, with no relapse in the symptoms.

Conclusion: It is important for clinicians to be aware of this diagnosis when managing patients with thyroid disease, because Riedel's thyroiditis can mimic malignancy. In addition, our case demonstrates that this condition should be treated with very high dose steroids to prevent relapse.

No MeSH data available.


Related in: MedlinePlus

Computed tomography (CT) scan of the neck and the thoracic outlet. This shows a large thyroid mass predominantly affecting the right lobe of the thyroid gland. The trachea has been pushed over to the left.
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Figure 1: Computed tomography (CT) scan of the neck and the thoracic outlet. This shows a large thyroid mass predominantly affecting the right lobe of the thyroid gland. The trachea has been pushed over to the left.

Mentions: A 59-year-old African-Caribbean man presented with a two-month history of neck pain, hoarse voice, dysphagia and breathing difficulties. He had an anterior neck swelling that increased rapidly in size. Clinical examination revealed an enlarged, hard and fixed goitre that was very tender on palpation. The trachea was deviated to the left side and there was no cervical lymphadenopathy. Fibre-optic laryngeal examination showed reduced mobility of the right vocal cord. Blood test showed a normal blood cell count and calcium and thyroid function tests, negative thyroid peroxidase autoantibodies and an erythrocyte sedimentation rate (ESR) of 95 mm/hr. A computed tomographic (CT) scan of the neck and thoracic outlet showed a large enhancing thyroid mass predominantly affecting the right lobe causing deviation of the trachea to the left with no cervical lymphadenopathy (Figure 1).


Riedel's thyroiditis masquerading as anaplastic thyroid carcinoma: a case report.

Shahi N, Abdelhamid MF, Jindall M, Awad RW - J Med Case Rep (2010)

Computed tomography (CT) scan of the neck and the thoracic outlet. This shows a large thyroid mass predominantly affecting the right lobe of the thyroid gland. The trachea has been pushed over to the left.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2821392&req=5

Figure 1: Computed tomography (CT) scan of the neck and the thoracic outlet. This shows a large thyroid mass predominantly affecting the right lobe of the thyroid gland. The trachea has been pushed over to the left.
Mentions: A 59-year-old African-Caribbean man presented with a two-month history of neck pain, hoarse voice, dysphagia and breathing difficulties. He had an anterior neck swelling that increased rapidly in size. Clinical examination revealed an enlarged, hard and fixed goitre that was very tender on palpation. The trachea was deviated to the left side and there was no cervical lymphadenopathy. Fibre-optic laryngeal examination showed reduced mobility of the right vocal cord. Blood test showed a normal blood cell count and calcium and thyroid function tests, negative thyroid peroxidase autoantibodies and an erythrocyte sedimentation rate (ESR) of 95 mm/hr. A computed tomographic (CT) scan of the neck and thoracic outlet showed a large enhancing thyroid mass predominantly affecting the right lobe causing deviation of the trachea to the left with no cervical lymphadenopathy (Figure 1).

Bottom Line: We discuss the presentation, investigation and management of this very rare condition.This was successfully treated with very high dose steroids, with no relapse in the symptoms.In addition, our case demonstrates that this condition should be treated with very high dose steroids to prevent relapse.

View Article: PubMed Central - HTML - PubMed

Affiliation: Warwick Hospital, Lakin house, Lakin Road, CV34 5BW, UK.

ABSTRACT

Introduction: Riedel's thyroiditis is a rare thyroid disease characterized by dense fibrous tissues that replace the thyroid gland and invade the adjacent structures that can mimic thyroid malignancy. We discuss the presentation, investigation and management of this very rare condition.

Case presentation: We present a case of a 59-year-old African-Caribbean man who presented with a rapidly growing hard neck mass, a hoarse voice, dysphagia and breathing difficulty that clinically suggested thyroid malignancy. Biopsy, however, revealed dense fibrous tissues suggestive of Riedel's thyroiditis. This was successfully treated with very high dose steroids, with no relapse in the symptoms.

Conclusion: It is important for clinicians to be aware of this diagnosis when managing patients with thyroid disease, because Riedel's thyroiditis can mimic malignancy. In addition, our case demonstrates that this condition should be treated with very high dose steroids to prevent relapse.

No MeSH data available.


Related in: MedlinePlus