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Facial skin metastasis of colorectal cancer: a case report.

Saladzinskas Z, Tamelis A, Paskauskas S, Pranys D, Pavalkis D - Cases J (2010)

Bottom Line: Metastasis of adenocarcinoma was confirmed histologically, and local excision was performed.No other metastasis or local recurrences were observed during the next 7 months.These patients have a worse prognosis.

View Article: PubMed Central - HTML - PubMed

Affiliation: Departments of Surgery, Kaunas University of Medicine, Kaunas, Eiveniu 2, 50009 Kaunas, Lithuania.

ABSTRACT

Introduction: Liver and lungs are common locations of distant metastases of colorectal cancer. Skin metastases of colorectal cancer are very rare, and facial lesions are extremely uncommon.

Case presentation: An anterior resection of the rectum was performed for rectal cancer T3N0M0G3. A small ulcer on the upper lip developed 3.5 years after primary operation. Metastasis of adenocarcinoma was confirmed histologically, and local excision was performed. At the same time, a solitary metastasis in the right lung was diagnosed, and the right lower lobectomy was performed. No other metastasis or local recurrences were observed during the next 7 months.

Conclusion: Skin metastases in the face from colorectal cancer are very rare and may indicate tumour relapse several years after primary resection. These patients have a worse prognosis.

No MeSH data available.


Related in: MedlinePlus

Immunohistochemically, the carcinoma cells, were focally positive for Cytokeratin (CK) 20 (a), but negative for CK 7 (b). This CK staining pattern suggested that the skin tumor was a metastasis from the previously resected rectal cancer.
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Figure 1: Immunohistochemically, the carcinoma cells, were focally positive for Cytokeratin (CK) 20 (a), but negative for CK 7 (b). This CK staining pattern suggested that the skin tumor was a metastasis from the previously resected rectal cancer.

Mentions: A small 0.5 cm diameter ulcer on the upper lip developed after 42 months following the removal of the primary tumor, and biopsy confirmed metastasis of the colorectal adenocarcinoma (Figure 1a. and 1b). This lesion was excised.


Facial skin metastasis of colorectal cancer: a case report.

Saladzinskas Z, Tamelis A, Paskauskas S, Pranys D, Pavalkis D - Cases J (2010)

Immunohistochemically, the carcinoma cells, were focally positive for Cytokeratin (CK) 20 (a), but negative for CK 7 (b). This CK staining pattern suggested that the skin tumor was a metastasis from the previously resected rectal cancer.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2821305&req=5

Figure 1: Immunohistochemically, the carcinoma cells, were focally positive for Cytokeratin (CK) 20 (a), but negative for CK 7 (b). This CK staining pattern suggested that the skin tumor was a metastasis from the previously resected rectal cancer.
Mentions: A small 0.5 cm diameter ulcer on the upper lip developed after 42 months following the removal of the primary tumor, and biopsy confirmed metastasis of the colorectal adenocarcinoma (Figure 1a. and 1b). This lesion was excised.

Bottom Line: Metastasis of adenocarcinoma was confirmed histologically, and local excision was performed.No other metastasis or local recurrences were observed during the next 7 months.These patients have a worse prognosis.

View Article: PubMed Central - HTML - PubMed

Affiliation: Departments of Surgery, Kaunas University of Medicine, Kaunas, Eiveniu 2, 50009 Kaunas, Lithuania.

ABSTRACT

Introduction: Liver and lungs are common locations of distant metastases of colorectal cancer. Skin metastases of colorectal cancer are very rare, and facial lesions are extremely uncommon.

Case presentation: An anterior resection of the rectum was performed for rectal cancer T3N0M0G3. A small ulcer on the upper lip developed 3.5 years after primary operation. Metastasis of adenocarcinoma was confirmed histologically, and local excision was performed. At the same time, a solitary metastasis in the right lung was diagnosed, and the right lower lobectomy was performed. No other metastasis or local recurrences were observed during the next 7 months.

Conclusion: Skin metastases in the face from colorectal cancer are very rare and may indicate tumour relapse several years after primary resection. These patients have a worse prognosis.

No MeSH data available.


Related in: MedlinePlus