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Coxsackievirus A6 and hand, foot, and mouth disease, Finland.

Osterback R, Vuorinen T, Linna M, Susi P, Hyypiä T, Waris M - Emerging Infect. Dis. (2009)

Bottom Line: During fall 2008, an outbreak of hand, foot, and mouth disease (HFMD) with onychomadesis (nail shedding) as a common feature occurred in Finland.We identified an unusual enterovirus type, coxsackievirus A6 (CVA6), as the causative agent.CVA6 infections may be emerging as a new and major cause of epidemic HFMD.

View Article: PubMed Central - PubMed

Affiliation: University of Turku, Turku, Finland.

ABSTRACT
During fall 2008, an outbreak of hand, foot, and mouth disease (HFMD) with onychomadesis (nail shedding) as a common feature occurred in Finland. We identified an unusual enterovirus type, coxsackievirus A6 (CVA6), as the causative agent. CVA6 infections may be emerging as a new and major cause of epidemic HFMD.

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Related in: MedlinePlus

Vesicular eruptions in A) hand, B) foot, and C) mouth of a 6.5-year-old boy from Turku, Finland, with coxsackievirus (CV) A6 infection. Several of his fingernails shed 2 months after the pictures were taken. D) Onychomadesis in a 10-year-old boy from Seinäjoki, Finland, 2 months after hand, foot and mouth disease with CVA6 infection. Photographs courtesy of H. Kujari (A–C) and M. Linna (D).
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Figure 1: Vesicular eruptions in A) hand, B) foot, and C) mouth of a 6.5-year-old boy from Turku, Finland, with coxsackievirus (CV) A6 infection. Several of his fingernails shed 2 months after the pictures were taken. D) Onychomadesis in a 10-year-old boy from Seinäjoki, Finland, 2 months after hand, foot and mouth disease with CVA6 infection. Photographs courtesy of H. Kujari (A–C) and M. Linna (D).

Mentions: Hand, foot, and mouth disease (HFMD) is a common childhood illness characterized by fever and vesicular eruptions on hands and feet and in the mouth (Figure 1). It is caused by members of the family Picornaviridae in the genus Enterovirus. Complications are rare, but pneumonia, meningitis, or encephalitis may occur. Outbreaks of HFMD have been mainly caused by 2 types of enterovirus A species, coxsackievirus (CV) A16 (CVA16) or enterovirus 71 (1). Some outbreaks have been associated with CVA10, but only sporadic cases involving other members of the enterovirus A species have been reported (2,3).


Coxsackievirus A6 and hand, foot, and mouth disease, Finland.

Osterback R, Vuorinen T, Linna M, Susi P, Hyypiä T, Waris M - Emerging Infect. Dis. (2009)

Vesicular eruptions in A) hand, B) foot, and C) mouth of a 6.5-year-old boy from Turku, Finland, with coxsackievirus (CV) A6 infection. Several of his fingernails shed 2 months after the pictures were taken. D) Onychomadesis in a 10-year-old boy from Seinäjoki, Finland, 2 months after hand, foot and mouth disease with CVA6 infection. Photographs courtesy of H. Kujari (A–C) and M. Linna (D).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2819858&req=5

Figure 1: Vesicular eruptions in A) hand, B) foot, and C) mouth of a 6.5-year-old boy from Turku, Finland, with coxsackievirus (CV) A6 infection. Several of his fingernails shed 2 months after the pictures were taken. D) Onychomadesis in a 10-year-old boy from Seinäjoki, Finland, 2 months after hand, foot and mouth disease with CVA6 infection. Photographs courtesy of H. Kujari (A–C) and M. Linna (D).
Mentions: Hand, foot, and mouth disease (HFMD) is a common childhood illness characterized by fever and vesicular eruptions on hands and feet and in the mouth (Figure 1). It is caused by members of the family Picornaviridae in the genus Enterovirus. Complications are rare, but pneumonia, meningitis, or encephalitis may occur. Outbreaks of HFMD have been mainly caused by 2 types of enterovirus A species, coxsackievirus (CV) A16 (CVA16) or enterovirus 71 (1). Some outbreaks have been associated with CVA10, but only sporadic cases involving other members of the enterovirus A species have been reported (2,3).

Bottom Line: During fall 2008, an outbreak of hand, foot, and mouth disease (HFMD) with onychomadesis (nail shedding) as a common feature occurred in Finland.We identified an unusual enterovirus type, coxsackievirus A6 (CVA6), as the causative agent.CVA6 infections may be emerging as a new and major cause of epidemic HFMD.

View Article: PubMed Central - PubMed

Affiliation: University of Turku, Turku, Finland.

ABSTRACT
During fall 2008, an outbreak of hand, foot, and mouth disease (HFMD) with onychomadesis (nail shedding) as a common feature occurred in Finland. We identified an unusual enterovirus type, coxsackievirus A6 (CVA6), as the causative agent. CVA6 infections may be emerging as a new and major cause of epidemic HFMD.

Show MeSH
Related in: MedlinePlus