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A multicenter investigation of OPTI-FREE RepleniSH multi-purpose disinfecting solution impact on soft contact lens patient comfort.

Corbin GS, Bennett L, Espejo L, Carducci S, Sacco A, Hannigan R, Schatz S - Clin Ophthalmol (2010)

Bottom Line: The test solution (OPTI-FREE((R)) RepleniSH((R)) MPDS) was dispensed for use in place of habitual care solutions.The test solution was associated with a statistically significant improvement in instillation comfort (P = 0.02), end of day comfort (P < 0.0001), clear vision (P < 0.0001) and overall satisfaction (P < 0.001).Subjects reported the test solution enhanced their overall lens-wearing experience more effectively than their previous solution (P < 0.0001) and that they would continue test solution use after the study (P < 0.0001).

View Article: PubMed Central - PubMed

Affiliation: Wyomissing Optometric Center, Wyomissing, PA, USA. drcorbin@wyoopto.com

ABSTRACT

Objective: Demonstrate that successful soft contact lens wearers using competitive multipurpose solutions report improvement in comfort with OPTI-FREE((R)) RepleniSH((R)) Multi-Purpose Disinfecting Solution (MPDS).

Methods: This 30-day, multicentered, open-label study enrolled 109 eligible soft contact lens wearers using COMPLETE((R)) Multi-Purpose Solution (MPS) Easy Rub((R)) or ReNu MultiPlus((R)) MPS. The test solution (OPTI-FREE((R)) RepleniSH((R)) MPDS) was dispensed for use in place of habitual care solutions. Subjects assessed their experience with their habitual solution (baseline) and the test solution (Day 30) using Likert-style questions. Contact lens acuity and biomicroscopy findings were recorded at each visit.

Results: The test solution was associated with a statistically significant improvement in instillation comfort (P = 0.02), end of day comfort (P < 0.0001), clear vision (P < 0.0001) and overall satisfaction (P < 0.001). Subjects reported the test solution enhanced their overall lens-wearing experience more effectively than their previous solution (P < 0.0001) and that they would continue test solution use after the study (P < 0.0001).

Conclusions: The test solution was effective at improving comfort and overall contact lens experience compared to COMPLETE((R)) MPS Easy Rub((R)) or ReNu MultiPlus((R)) MPS in successful contact lens wearers. These results indicate that changing contact lens care solutions, even in successful lens wearers, may improve comfort and overall lens-wearing experience.

No MeSH data available.


End of day vision. “My vision is clear at the end of the lens-wearing day.”Note: P-value < 0.0001.
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f3-opth-4-047: End of day vision. “My vision is clear at the end of the lens-wearing day.”Note: P-value < 0.0001.

Mentions: Responses to study questionnaire A (Day 0) were compared with those from study questionnaire B (Day 30). Subjects rated the test solution significantly better for all four subjective statements, including lens instillation comfort (P = 0.02, Figure 1); end of day comfort (P < 0.0001, Figure 2); clear vision at the end of the lens-wearing day (P < 0.0001, Figure 3) and overall satisfaction (P < 0.001, Figure 4) compared to their previous solution.


A multicenter investigation of OPTI-FREE RepleniSH multi-purpose disinfecting solution impact on soft contact lens patient comfort.

Corbin GS, Bennett L, Espejo L, Carducci S, Sacco A, Hannigan R, Schatz S - Clin Ophthalmol (2010)

End of day vision. “My vision is clear at the end of the lens-wearing day.”Note: P-value < 0.0001.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2819769&req=5

f3-opth-4-047: End of day vision. “My vision is clear at the end of the lens-wearing day.”Note: P-value < 0.0001.
Mentions: Responses to study questionnaire A (Day 0) were compared with those from study questionnaire B (Day 30). Subjects rated the test solution significantly better for all four subjective statements, including lens instillation comfort (P = 0.02, Figure 1); end of day comfort (P < 0.0001, Figure 2); clear vision at the end of the lens-wearing day (P < 0.0001, Figure 3) and overall satisfaction (P < 0.001, Figure 4) compared to their previous solution.

Bottom Line: The test solution (OPTI-FREE((R)) RepleniSH((R)) MPDS) was dispensed for use in place of habitual care solutions.The test solution was associated with a statistically significant improvement in instillation comfort (P = 0.02), end of day comfort (P < 0.0001), clear vision (P < 0.0001) and overall satisfaction (P < 0.001).Subjects reported the test solution enhanced their overall lens-wearing experience more effectively than their previous solution (P < 0.0001) and that they would continue test solution use after the study (P < 0.0001).

View Article: PubMed Central - PubMed

Affiliation: Wyomissing Optometric Center, Wyomissing, PA, USA. drcorbin@wyoopto.com

ABSTRACT

Objective: Demonstrate that successful soft contact lens wearers using competitive multipurpose solutions report improvement in comfort with OPTI-FREE((R)) RepleniSH((R)) Multi-Purpose Disinfecting Solution (MPDS).

Methods: This 30-day, multicentered, open-label study enrolled 109 eligible soft contact lens wearers using COMPLETE((R)) Multi-Purpose Solution (MPS) Easy Rub((R)) or ReNu MultiPlus((R)) MPS. The test solution (OPTI-FREE((R)) RepleniSH((R)) MPDS) was dispensed for use in place of habitual care solutions. Subjects assessed their experience with their habitual solution (baseline) and the test solution (Day 30) using Likert-style questions. Contact lens acuity and biomicroscopy findings were recorded at each visit.

Results: The test solution was associated with a statistically significant improvement in instillation comfort (P = 0.02), end of day comfort (P < 0.0001), clear vision (P < 0.0001) and overall satisfaction (P < 0.001). Subjects reported the test solution enhanced their overall lens-wearing experience more effectively than their previous solution (P < 0.0001) and that they would continue test solution use after the study (P < 0.0001).

Conclusions: The test solution was effective at improving comfort and overall contact lens experience compared to COMPLETE((R)) MPS Easy Rub((R)) or ReNu MultiPlus((R)) MPS in successful contact lens wearers. These results indicate that changing contact lens care solutions, even in successful lens wearers, may improve comfort and overall lens-wearing experience.

No MeSH data available.