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Amyloidosis of lacrimal gland.

Prabhakaran VC, Babu K, Mahadevan A, Murthy SR - Indian J Ophthalmol (2009 Nov-Dec)

Bottom Line: A 45-year-old Indian woman presented with a swelling over the left lacrimal gland region.Computed tomography showed uniform enlargement of the lacrimal gland.No systemic involvement was detected on further investigation.

View Article: PubMed Central - PubMed

Affiliation: Department of Orbit and Oculoplastic Surgery, and Ophthalmic Pathology, Prabha Eye Clinic and Vittala International Institute of Ophthalmology, NIMHANS, Bangalore, India. cpvenky@gmail.com

ABSTRACT
Primary localized amyloidosis of lacrimal gland is a rare occurrence. This report describes a female patient with isolated amyloidosis of the lacrimal gland. A 45-year-old Indian woman presented with a swelling over the left lacrimal gland region. Computed tomography showed uniform enlargement of the lacrimal gland. A lacrimal gland biopsy revealed amyloidosis. No systemic involvement was detected on further investigation. To our knowledge, this is the first report of lacrimal gland amyloidosis from India and our report also highlights the importance of lacrimal gland biopsy in diagnosing lacrimal gland masses.

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Clinical photograph showing left ptosis and inferior globe displacement
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Figure 0001: Clinical photograph showing left ptosis and inferior globe displacement

Mentions: A 45-year-old Indian woman presented with a slowly progressive swelling of the left upper eyelid of three months duration. This was associated with discomfort but was not painful. On examination, the best-corrected visual acuity was 20/20 in both eyes. Left eye examination showed lateral ptosis with S-shaped deformity of the lid [Fig. 1]. A firm, non-tender mass was palpated in the supero-temporal orbit. Hertel's exophthalmometry showed a 2 mm proptosis of the left eye with 2 mm of inferior displacement. The extraocular movements were restricted in levo-elevation, but diplopia could not be elicited. The anterior segment and fundus examinations were normal. The right eye examination was unremarkable.


Amyloidosis of lacrimal gland.

Prabhakaran VC, Babu K, Mahadevan A, Murthy SR - Indian J Ophthalmol (2009 Nov-Dec)

Clinical photograph showing left ptosis and inferior globe displacement
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2812767&req=5

Figure 0001: Clinical photograph showing left ptosis and inferior globe displacement
Mentions: A 45-year-old Indian woman presented with a slowly progressive swelling of the left upper eyelid of three months duration. This was associated with discomfort but was not painful. On examination, the best-corrected visual acuity was 20/20 in both eyes. Left eye examination showed lateral ptosis with S-shaped deformity of the lid [Fig. 1]. A firm, non-tender mass was palpated in the supero-temporal orbit. Hertel's exophthalmometry showed a 2 mm proptosis of the left eye with 2 mm of inferior displacement. The extraocular movements were restricted in levo-elevation, but diplopia could not be elicited. The anterior segment and fundus examinations were normal. The right eye examination was unremarkable.

Bottom Line: A 45-year-old Indian woman presented with a swelling over the left lacrimal gland region.Computed tomography showed uniform enlargement of the lacrimal gland.No systemic involvement was detected on further investigation.

View Article: PubMed Central - PubMed

Affiliation: Department of Orbit and Oculoplastic Surgery, and Ophthalmic Pathology, Prabha Eye Clinic and Vittala International Institute of Ophthalmology, NIMHANS, Bangalore, India. cpvenky@gmail.com

ABSTRACT
Primary localized amyloidosis of lacrimal gland is a rare occurrence. This report describes a female patient with isolated amyloidosis of the lacrimal gland. A 45-year-old Indian woman presented with a swelling over the left lacrimal gland region. Computed tomography showed uniform enlargement of the lacrimal gland. A lacrimal gland biopsy revealed amyloidosis. No systemic involvement was detected on further investigation. To our knowledge, this is the first report of lacrimal gland amyloidosis from India and our report also highlights the importance of lacrimal gland biopsy in diagnosing lacrimal gland masses.

Show MeSH
Related in: MedlinePlus