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Practical and clinical considerations in Cobalt-60 tomotherapy.

Joshi CP, Dhanesar S, Darko J, Kerr A, Vidyasagar PB, Schreiner LJ - J Med Phys (2009)

Bottom Line: The tomotherapy IMRT plans were obtained by modeling a MIMiC binary multi-leaf collimator attached to a Theratron-780c Co-60 unit and a 6 MV linear accelerator (CL2100EX).The EGSnrc/BEAMnrc Monte Carlo (MC) code was used for the modeling of the treatment units with the MIMiC collimator and EGSnrc/DOSXYZnrc code was used for beamlet dose data.A quantitative analysis of the dose distributions and dose-volume histograms shows that both Co-60 and 6 MV plans achieve the plan objectives for the targets (CTV and nodes) and OARs (spinal cord in HandN case, and rectum in prostate case).

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Physics, Cancer Centre of Southeastern Ontario (CCSEO), Kingston, ON, Canada.

ABSTRACT
Cobalt-60 (Co-60) based radiation therapy continues to play a significant role in not only developing countries, where access to radiation therapy is extremely limited, but also in industrialized countries. Howver, technology has to be developed to accommodate modern techniques, including image guided and adaptive radiation therapy (IGART). In this paper we describe some of the practical and clinical considerations for Co-60 based tomotherapy by comparing Co-60 and 6 MV linac-based tomotherapy plans for a head and neck (HandN) cancer and a prostate cancer case. The tomotherapy IMRT plans were obtained by modeling a MIMiC binary multi-leaf collimator attached to a Theratron-780c Co-60 unit and a 6 MV linear accelerator (CL2100EX). The EGSnrc/BEAMnrc Monte Carlo (MC) code was used for the modeling of the treatment units with the MIMiC collimator and EGSnrc/DOSXYZnrc code was used for beamlet dose data. An in-house inverse treatment planning program was then used to generate optimized tomotherapy dose distributions for the H and N and prostate cases. The dose distributions, cumulative dose area histograms (DAHs) and dose difference maps were used to evaluate and compare Co-60 and 6 MV based tomotherapy plans. A quantitative analysis of the dose distributions and dose-volume histograms shows that both Co-60 and 6 MV plans achieve the plan objectives for the targets (CTV and nodes) and OARs (spinal cord in HandN case, and rectum in prostate case).

No MeSH data available.


Related in: MedlinePlus

Tomotherapy plans for Co-60 and 6 MV beams for a prostate case, achieved by modulating the intensity of 210 beamlets (10 beamlets per orientation and 21 equally spaced field orientations)
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Figure 0003: Tomotherapy plans for Co-60 and 6 MV beams for a prostate case, achieved by modulating the intensity of 210 beamlets (10 beamlets per orientation and 21 equally spaced field orientations)

Mentions: Figure 3 shows the conformal dose distributions for a prostate case generated using Co-60 and 6 MV linac based tomotherapy. As desired, the high dose treatment for both tomotherapy plans is concentrated within the prostate and only a small portion of the rectum receives a high dose. The dose to the external body is also limited. These results prove that it is possible to provide a highly conformal radiation therapy via Co-60 based tomotherapy when treating deep seated tumor situated in anatomical regions with large separations such as the pelvis.


Practical and clinical considerations in Cobalt-60 tomotherapy.

Joshi CP, Dhanesar S, Darko J, Kerr A, Vidyasagar PB, Schreiner LJ - J Med Phys (2009)

Tomotherapy plans for Co-60 and 6 MV beams for a prostate case, achieved by modulating the intensity of 210 beamlets (10 beamlets per orientation and 21 equally spaced field orientations)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2807678&req=5

Figure 0003: Tomotherapy plans for Co-60 and 6 MV beams for a prostate case, achieved by modulating the intensity of 210 beamlets (10 beamlets per orientation and 21 equally spaced field orientations)
Mentions: Figure 3 shows the conformal dose distributions for a prostate case generated using Co-60 and 6 MV linac based tomotherapy. As desired, the high dose treatment for both tomotherapy plans is concentrated within the prostate and only a small portion of the rectum receives a high dose. The dose to the external body is also limited. These results prove that it is possible to provide a highly conformal radiation therapy via Co-60 based tomotherapy when treating deep seated tumor situated in anatomical regions with large separations such as the pelvis.

Bottom Line: The tomotherapy IMRT plans were obtained by modeling a MIMiC binary multi-leaf collimator attached to a Theratron-780c Co-60 unit and a 6 MV linear accelerator (CL2100EX).The EGSnrc/BEAMnrc Monte Carlo (MC) code was used for the modeling of the treatment units with the MIMiC collimator and EGSnrc/DOSXYZnrc code was used for beamlet dose data.A quantitative analysis of the dose distributions and dose-volume histograms shows that both Co-60 and 6 MV plans achieve the plan objectives for the targets (CTV and nodes) and OARs (spinal cord in HandN case, and rectum in prostate case).

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Physics, Cancer Centre of Southeastern Ontario (CCSEO), Kingston, ON, Canada.

ABSTRACT
Cobalt-60 (Co-60) based radiation therapy continues to play a significant role in not only developing countries, where access to radiation therapy is extremely limited, but also in industrialized countries. Howver, technology has to be developed to accommodate modern techniques, including image guided and adaptive radiation therapy (IGART). In this paper we describe some of the practical and clinical considerations for Co-60 based tomotherapy by comparing Co-60 and 6 MV linac-based tomotherapy plans for a head and neck (HandN) cancer and a prostate cancer case. The tomotherapy IMRT plans were obtained by modeling a MIMiC binary multi-leaf collimator attached to a Theratron-780c Co-60 unit and a 6 MV linear accelerator (CL2100EX). The EGSnrc/BEAMnrc Monte Carlo (MC) code was used for the modeling of the treatment units with the MIMiC collimator and EGSnrc/DOSXYZnrc code was used for beamlet dose data. An in-house inverse treatment planning program was then used to generate optimized tomotherapy dose distributions for the H and N and prostate cases. The dose distributions, cumulative dose area histograms (DAHs) and dose difference maps were used to evaluate and compare Co-60 and 6 MV based tomotherapy plans. A quantitative analysis of the dose distributions and dose-volume histograms shows that both Co-60 and 6 MV plans achieve the plan objectives for the targets (CTV and nodes) and OARs (spinal cord in HandN case, and rectum in prostate case).

No MeSH data available.


Related in: MedlinePlus