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The role of Cobalt-60 in modern radiation therapy: Dose delivery and image guidance.

Schreiner LJ, Joshi CP, Darko J, Kerr A, Salomons G, Dhanesar S - J Med Phys (2009)

Bottom Line: The advances in modern radiation therapy with techniques such as intensity-modulated radiation therapy and image-guided radiation therapy (IMRT and IGRT) have been limited almost exclusively to linear accelerators.Investigations of modern Cobalt-60 (Co-60) radiation delivery in the context of IMRT and IGRT have been very sparse, and have been limited mainly to computer-modeling and treatment-planning exercises.We show that conformal dose delivery is possible and also that Co-60 can be used as the radiation source in megavoltage computed tomography imaging.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Physics, Cancer Centre of Southeastern Ontario (CCSEO), Kingston, ON, Canada.

ABSTRACT
The advances in modern radiation therapy with techniques such as intensity-modulated radiation therapy and image-guided radiation therapy (IMRT and IGRT) have been limited almost exclusively to linear accelerators. Investigations of modern Cobalt-60 (Co-60) radiation delivery in the context of IMRT and IGRT have been very sparse, and have been limited mainly to computer-modeling and treatment-planning exercises. In this paper, we report on the results of experiments using a tomotherapy benchtop apparatus attached to a conventional Co-60 unit. We show that conformal dose delivery is possible and also that Co-60 can be used as the radiation source in megavoltage computed tomography imaging. These results complement our modeling studies of Co-60 tomotherapy and provide a strong motivation for continuing development of modern Cobalt-60 treatment devices.

No MeSH data available.


Cobalt-60–based tomotherapy plans of a “ring”-shaped structure (a) and an exaggerated concave “C” structure (b). Top: The dose distributions obtained with our in-house inverse treatment planning system; middle: the deliveries of both patterns on GafChromic film; bottom: gamma maps of the plans and deliveries using 5%, 5 mm gamma criteria
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Figure 0002: Cobalt-60–based tomotherapy plans of a “ring”-shaped structure (a) and an exaggerated concave “C” structure (b). Top: The dose distributions obtained with our in-house inverse treatment planning system; middle: the deliveries of both patterns on GafChromic film; bottom: gamma maps of the plans and deliveries using 5%, 5 mm gamma criteria

Mentions: The findings to date confirm the viability of Co-60–based tomotherapy for conformal dose delivery. Figure 2 shows two examples of conformal irradiations planned for the delivery with the in-house cylindrical treatment phantom — a ring pattern [Figure 2a] and a standard conformal avoidance ‘C’ plan [Figure 2b]. These plans were implemented to determine whether the inverse treatment planning system would be able to generate an optimized and accurate dose distribution for simple but challenging geometry, including the ability to protect the central critical structure from unwanted radiation.


The role of Cobalt-60 in modern radiation therapy: Dose delivery and image guidance.

Schreiner LJ, Joshi CP, Darko J, Kerr A, Salomons G, Dhanesar S - J Med Phys (2009)

Cobalt-60–based tomotherapy plans of a “ring”-shaped structure (a) and an exaggerated concave “C” structure (b). Top: The dose distributions obtained with our in-house inverse treatment planning system; middle: the deliveries of both patterns on GafChromic film; bottom: gamma maps of the plans and deliveries using 5%, 5 mm gamma criteria
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2807677&req=5

Figure 0002: Cobalt-60–based tomotherapy plans of a “ring”-shaped structure (a) and an exaggerated concave “C” structure (b). Top: The dose distributions obtained with our in-house inverse treatment planning system; middle: the deliveries of both patterns on GafChromic film; bottom: gamma maps of the plans and deliveries using 5%, 5 mm gamma criteria
Mentions: The findings to date confirm the viability of Co-60–based tomotherapy for conformal dose delivery. Figure 2 shows two examples of conformal irradiations planned for the delivery with the in-house cylindrical treatment phantom — a ring pattern [Figure 2a] and a standard conformal avoidance ‘C’ plan [Figure 2b]. These plans were implemented to determine whether the inverse treatment planning system would be able to generate an optimized and accurate dose distribution for simple but challenging geometry, including the ability to protect the central critical structure from unwanted radiation.

Bottom Line: The advances in modern radiation therapy with techniques such as intensity-modulated radiation therapy and image-guided radiation therapy (IMRT and IGRT) have been limited almost exclusively to linear accelerators.Investigations of modern Cobalt-60 (Co-60) radiation delivery in the context of IMRT and IGRT have been very sparse, and have been limited mainly to computer-modeling and treatment-planning exercises.We show that conformal dose delivery is possible and also that Co-60 can be used as the radiation source in megavoltage computed tomography imaging.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Physics, Cancer Centre of Southeastern Ontario (CCSEO), Kingston, ON, Canada.

ABSTRACT
The advances in modern radiation therapy with techniques such as intensity-modulated radiation therapy and image-guided radiation therapy (IMRT and IGRT) have been limited almost exclusively to linear accelerators. Investigations of modern Cobalt-60 (Co-60) radiation delivery in the context of IMRT and IGRT have been very sparse, and have been limited mainly to computer-modeling and treatment-planning exercises. In this paper, we report on the results of experiments using a tomotherapy benchtop apparatus attached to a conventional Co-60 unit. We show that conformal dose delivery is possible and also that Co-60 can be used as the radiation source in megavoltage computed tomography imaging. These results complement our modeling studies of Co-60 tomotherapy and provide a strong motivation for continuing development of modern Cobalt-60 treatment devices.

No MeSH data available.