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Flow pumping system for physiological waveforms.

Tsai W, Savaş O - Med Biol Eng Comput (2010)

Bottom Line: The system divides the task of flow waveform generation between two pumps: a gear pump generates the mean component and a piston pump generates the oscillatory component.The frequency response of the system is used to characterize its operation.The system has been successfully tested in vascular flow experiments where sinusoidal, carotid, and coronary flow waveforms are replicated.

View Article: PubMed Central - PubMed

Affiliation: Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA 94720, USA. wtsai@berkeley.edu

ABSTRACT
A pulsatile flow pumping system is developed to replicate flow waveforms with reasonable accuracy for experiments simulating physiological blood flows at numerous points in the body. The system divides the task of flow waveform generation between two pumps: a gear pump generates the mean component and a piston pump generates the oscillatory component. The system is driven by two programmable servo controllers. The frequency response of the system is used to characterize its operation. The system has been successfully tested in vascular flow experiments where sinusoidal, carotid, and coronary flow waveforms are replicated.

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Diagram (a) and photograph (b) of the gear–piston pumping system
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Fig1: Diagram (a) and photograph (b) of the gear–piston pumping system

Mentions: The pulsatile pumping system consists of a combination of a gear and a piston pump in series (Fig. 1). All components are mounted on a plate for easy access. The Teflon-coated stainless steel gear pump provides the steady mean component of the desired flow waveform. Unlike previous designs, the output gear pump does not oscillate, instead is operated under a constant load. The gear pump is preloaded with a back-pressure valve at its discharge. The back-pressure valve consists of a spring loaded diaphragm designed to apply a positive pressure to the flow in the event downstream pressures are greater than the gear pump outlet pressure. This ensures that the gears remain in constant contact to prevent reverse flow. For this experimental setup, an Oberdorfer Chemsteel S207 Pump (Oberdorfer Pumps, Syracuse, NY, USA) is used with a maximum throughput of 300 ml/s. A Nikkiso HydroGarD back-pressure valve (Nikkiso Pumps, Houston, TX, USA) is placed at the discharge of the gear pump.Fig. 1


Flow pumping system for physiological waveforms.

Tsai W, Savaş O - Med Biol Eng Comput (2010)

Diagram (a) and photograph (b) of the gear–piston pumping system
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2807595&req=5

Fig1: Diagram (a) and photograph (b) of the gear–piston pumping system
Mentions: The pulsatile pumping system consists of a combination of a gear and a piston pump in series (Fig. 1). All components are mounted on a plate for easy access. The Teflon-coated stainless steel gear pump provides the steady mean component of the desired flow waveform. Unlike previous designs, the output gear pump does not oscillate, instead is operated under a constant load. The gear pump is preloaded with a back-pressure valve at its discharge. The back-pressure valve consists of a spring loaded diaphragm designed to apply a positive pressure to the flow in the event downstream pressures are greater than the gear pump outlet pressure. This ensures that the gears remain in constant contact to prevent reverse flow. For this experimental setup, an Oberdorfer Chemsteel S207 Pump (Oberdorfer Pumps, Syracuse, NY, USA) is used with a maximum throughput of 300 ml/s. A Nikkiso HydroGarD back-pressure valve (Nikkiso Pumps, Houston, TX, USA) is placed at the discharge of the gear pump.Fig. 1

Bottom Line: The system divides the task of flow waveform generation between two pumps: a gear pump generates the mean component and a piston pump generates the oscillatory component.The frequency response of the system is used to characterize its operation.The system has been successfully tested in vascular flow experiments where sinusoidal, carotid, and coronary flow waveforms are replicated.

View Article: PubMed Central - PubMed

Affiliation: Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA 94720, USA. wtsai@berkeley.edu

ABSTRACT
A pulsatile flow pumping system is developed to replicate flow waveforms with reasonable accuracy for experiments simulating physiological blood flows at numerous points in the body. The system divides the task of flow waveform generation between two pumps: a gear pump generates the mean component and a piston pump generates the oscillatory component. The system is driven by two programmable servo controllers. The frequency response of the system is used to characterize its operation. The system has been successfully tested in vascular flow experiments where sinusoidal, carotid, and coronary flow waveforms are replicated.

Show MeSH