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Normolipemic tuberous xanthomas.

Singh AP, Sikarwar S, Jatav OP, Saify K - Indian J Dermatol (2009)

Bottom Line: A 50-year-old male presented to our hospital with the lesions of multiple tuberous xanthomas all over the body.Routine investigations and systemic examination were normal.Histopathology from a nodular lesion showed collection of foamy macrophages in the dermis.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, G.R. Medical College, Gwalior - 474 009, MP, India. drajaypalsingh4@rediffmail.com

ABSTRACT
Xanthomas are often a manifestation of underlying lipid abnormalities. A 50-year-old male presented to our hospital with the lesions of multiple tuberous xanthomas all over the body. Routine investigations and systemic examination were normal. Lipid profile was within normal range and serum protein electrophoresis showed normal pattern. Histopathology from a nodular lesion showed collection of foamy macrophages in the dermis. We present a case of normolipemic tuberous xanthomas, which is an uncommon occurrence.

No MeSH data available.


Related in: MedlinePlus

Microphotograph illustrates foamy macrophages [H&E, ×40]
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Figure 0010: Microphotograph illustrates foamy macrophages [H&E, ×40]

Mentions: Routine investigations including complete hemogram and urine analysis were normal. Other investigations revealed normal lipid profile, thyroid, liver and kidney function tests, and blood sugar levels. The results of chest X-ray, E.C.G, and ultrasonography of abdomen were normal. Serum protein electrophoresis showed normal pattern. The histopathological evaluation from one of the nodules showed thinned out epidermis with collection of lobules of foamy macrophages separated by fibrous bands [Figures 9 and 10]. The patient was kept on follow up and repeated lipid profile after one month showed almost similar values. Cryotherapy with nitrous oxide was done for large tuberous xanthomas along with oral antioxidants. Patient is responding well to the treatment. The skin lesions are healing and he is still under follow-up.


Normolipemic tuberous xanthomas.

Singh AP, Sikarwar S, Jatav OP, Saify K - Indian J Dermatol (2009)

Microphotograph illustrates foamy macrophages [H&E, ×40]
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2807159&req=5

Figure 0010: Microphotograph illustrates foamy macrophages [H&E, ×40]
Mentions: Routine investigations including complete hemogram and urine analysis were normal. Other investigations revealed normal lipid profile, thyroid, liver and kidney function tests, and blood sugar levels. The results of chest X-ray, E.C.G, and ultrasonography of abdomen were normal. Serum protein electrophoresis showed normal pattern. The histopathological evaluation from one of the nodules showed thinned out epidermis with collection of lobules of foamy macrophages separated by fibrous bands [Figures 9 and 10]. The patient was kept on follow up and repeated lipid profile after one month showed almost similar values. Cryotherapy with nitrous oxide was done for large tuberous xanthomas along with oral antioxidants. Patient is responding well to the treatment. The skin lesions are healing and he is still under follow-up.

Bottom Line: A 50-year-old male presented to our hospital with the lesions of multiple tuberous xanthomas all over the body.Routine investigations and systemic examination were normal.Histopathology from a nodular lesion showed collection of foamy macrophages in the dermis.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, G.R. Medical College, Gwalior - 474 009, MP, India. drajaypalsingh4@rediffmail.com

ABSTRACT
Xanthomas are often a manifestation of underlying lipid abnormalities. A 50-year-old male presented to our hospital with the lesions of multiple tuberous xanthomas all over the body. Routine investigations and systemic examination were normal. Lipid profile was within normal range and serum protein electrophoresis showed normal pattern. Histopathology from a nodular lesion showed collection of foamy macrophages in the dermis. We present a case of normolipemic tuberous xanthomas, which is an uncommon occurrence.

No MeSH data available.


Related in: MedlinePlus