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Malignant eccrine spiradenoma on the lateral margin of nose as an infrequent localization.

Berçin S, Kutluhan A, Metin A, Süren D - Indian J Dermatol (2009)

Bottom Line: They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor.Low-grade malignant eccrine spiradenoma has a better prognosis.We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Atatürk Training and Research Hospital, Ankara, Turkey. sbercin@hotmail.com

ABSTRACT
Malignant eccrine spiradenomas are exceedingly rare tumors. They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor. Clinical features of these tumors may include a history of enlargement in a previously stable lesion. Tumor can be of low or high grade. Low-grade malignant eccrine spiradenoma has a better prognosis. We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

No MeSH data available.


Related in: MedlinePlus

Focal tumor cell necrosis is seen through out the tumor (H&E, ×200)
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Figure 0004: Focal tumor cell necrosis is seen through out the tumor (H&E, ×200)

Mentions: The resulting appereance resembles an eccrine spiradenoma. However in some areas, the tumor showed malignant change. These malignant components were composed of solid aggregates of tumor cells with mild to modarate nuclear atypia, high mitotic figures (12/10 high-power field) and focal tumor cell necrosis [Figures 3 and 4]. Vascular invasion was not present. The surgical margins of excision were free of tumor. The pathologic findings were concordant with transformation to malignant eccrine spiradenoma because of the absence of palpable or ultrasonographic lymph node in head and neck and metastasis in adjacent structures like paranasal sinuses. Close follow-up was initiated.


Malignant eccrine spiradenoma on the lateral margin of nose as an infrequent localization.

Berçin S, Kutluhan A, Metin A, Süren D - Indian J Dermatol (2009)

Focal tumor cell necrosis is seen through out the tumor (H&E, ×200)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2807158&req=5

Figure 0004: Focal tumor cell necrosis is seen through out the tumor (H&E, ×200)
Mentions: The resulting appereance resembles an eccrine spiradenoma. However in some areas, the tumor showed malignant change. These malignant components were composed of solid aggregates of tumor cells with mild to modarate nuclear atypia, high mitotic figures (12/10 high-power field) and focal tumor cell necrosis [Figures 3 and 4]. Vascular invasion was not present. The surgical margins of excision were free of tumor. The pathologic findings were concordant with transformation to malignant eccrine spiradenoma because of the absence of palpable or ultrasonographic lymph node in head and neck and metastasis in adjacent structures like paranasal sinuses. Close follow-up was initiated.

Bottom Line: They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor.Low-grade malignant eccrine spiradenoma has a better prognosis.We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Atatürk Training and Research Hospital, Ankara, Turkey. sbercin@hotmail.com

ABSTRACT
Malignant eccrine spiradenomas are exceedingly rare tumors. They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor. Clinical features of these tumors may include a history of enlargement in a previously stable lesion. Tumor can be of low or high grade. Low-grade malignant eccrine spiradenoma has a better prognosis. We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

No MeSH data available.


Related in: MedlinePlus