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Malignant eccrine spiradenoma on the lateral margin of nose as an infrequent localization.

Berçin S, Kutluhan A, Metin A, Süren D - Indian J Dermatol (2009)

Bottom Line: They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor.Low-grade malignant eccrine spiradenoma has a better prognosis.We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Atatürk Training and Research Hospital, Ankara, Turkey. sbercin@hotmail.com

ABSTRACT
Malignant eccrine spiradenomas are exceedingly rare tumors. They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor. Clinical features of these tumors may include a history of enlargement in a previously stable lesion. Tumor can be of low or high grade. Low-grade malignant eccrine spiradenoma has a better prognosis. We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

No MeSH data available.


Related in: MedlinePlus

Solid areas of the tumor composed of malignant cells with nuclear atypia and high mitotic figures (left). The other component resembled an ecrine spiradenoma; with two distinct cell proliferation and tubule formations (right) (H&E, ×100)
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Figure 0003: Solid areas of the tumor composed of malignant cells with nuclear atypia and high mitotic figures (left). The other component resembled an ecrine spiradenoma; with two distinct cell proliferation and tubule formations (right) (H&E, ×100)

Mentions: At higher magnifications, two distinct populations of neoplastic epithelial cells (small dark basaloid cells and pale cells, which are larger with vesicular nuclei and pale cytoplasm) and tubule formations were characteristic features of the tumor. Tubules lined by two rows of epithelial cells were found within the tumor. The presence of basaloid secretion material, some surrounded by neoplastic cells, throughout the neoplasm attracted attention [Figure 3].


Malignant eccrine spiradenoma on the lateral margin of nose as an infrequent localization.

Berçin S, Kutluhan A, Metin A, Süren D - Indian J Dermatol (2009)

Solid areas of the tumor composed of malignant cells with nuclear atypia and high mitotic figures (left). The other component resembled an ecrine spiradenoma; with two distinct cell proliferation and tubule formations (right) (H&E, ×100)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2807158&req=5

Figure 0003: Solid areas of the tumor composed of malignant cells with nuclear atypia and high mitotic figures (left). The other component resembled an ecrine spiradenoma; with two distinct cell proliferation and tubule formations (right) (H&E, ×100)
Mentions: At higher magnifications, two distinct populations of neoplastic epithelial cells (small dark basaloid cells and pale cells, which are larger with vesicular nuclei and pale cytoplasm) and tubule formations were characteristic features of the tumor. Tubules lined by two rows of epithelial cells were found within the tumor. The presence of basaloid secretion material, some surrounded by neoplastic cells, throughout the neoplasm attracted attention [Figure 3].

Bottom Line: They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor.Low-grade malignant eccrine spiradenoma has a better prognosis.We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Atatürk Training and Research Hospital, Ankara, Turkey. sbercin@hotmail.com

ABSTRACT
Malignant eccrine spiradenomas are exceedingly rare tumors. They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor. Clinical features of these tumors may include a history of enlargement in a previously stable lesion. Tumor can be of low or high grade. Low-grade malignant eccrine spiradenoma has a better prognosis. We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

No MeSH data available.


Related in: MedlinePlus