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Malignant eccrine spiradenoma on the lateral margin of nose as an infrequent localization.

Berçin S, Kutluhan A, Metin A, Süren D - Indian J Dermatol (2009)

Bottom Line: They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor.Low-grade malignant eccrine spiradenoma has a better prognosis.We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Atatürk Training and Research Hospital, Ankara, Turkey. sbercin@hotmail.com

ABSTRACT
Malignant eccrine spiradenomas are exceedingly rare tumors. They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor. Clinical features of these tumors may include a history of enlargement in a previously stable lesion. Tumor can be of low or high grade. Low-grade malignant eccrine spiradenoma has a better prognosis. We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

No MeSH data available.


Related in: MedlinePlus

Appearence of the lesion on lateral part of nose and anteriorinferior aspect of medial canthus
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Figure 0001: Appearence of the lesion on lateral part of nose and anteriorinferior aspect of medial canthus

Mentions: A 64-year-old female patient was admitted to our department, with a 1 × 1 cm swelling on her upper lateral aspect of her nose, which had been present for 6 months. She had noticed a sudden enlargment of the painless, dark pink-blue noduler lesion on her nose for the past two months [Figure 1]. There was no palpable lymph node in the neck. The lesion was excised with a 5 mm free margin and the wound was closed by primary suturation. Gross examination of the resected specimen showed a 1 × 1 cm, pink–blue noduler lesion. The specimen was fixed in a 10% neutral buffered formaldehyde solution and embedded in paraffin. It was routinely processed with hematoxylin and eosin staining. Microscopic examination revealed a nodular tumor located in the dermis. The overlying epidermis demonstrated hyperplastic changes. A heavy lymphocytic infiltration was present mainly at the peripheral portions of the tumor, but some were also scattered between the tumor cells [Figure 2].


Malignant eccrine spiradenoma on the lateral margin of nose as an infrequent localization.

Berçin S, Kutluhan A, Metin A, Süren D - Indian J Dermatol (2009)

Appearence of the lesion on lateral part of nose and anteriorinferior aspect of medial canthus
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2807158&req=5

Figure 0001: Appearence of the lesion on lateral part of nose and anteriorinferior aspect of medial canthus
Mentions: A 64-year-old female patient was admitted to our department, with a 1 × 1 cm swelling on her upper lateral aspect of her nose, which had been present for 6 months. She had noticed a sudden enlargment of the painless, dark pink-blue noduler lesion on her nose for the past two months [Figure 1]. There was no palpable lymph node in the neck. The lesion was excised with a 5 mm free margin and the wound was closed by primary suturation. Gross examination of the resected specimen showed a 1 × 1 cm, pink–blue noduler lesion. The specimen was fixed in a 10% neutral buffered formaldehyde solution and embedded in paraffin. It was routinely processed with hematoxylin and eosin staining. Microscopic examination revealed a nodular tumor located in the dermis. The overlying epidermis demonstrated hyperplastic changes. A heavy lymphocytic infiltration was present mainly at the peripheral portions of the tumor, but some were also scattered between the tumor cells [Figure 2].

Bottom Line: They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor.Low-grade malignant eccrine spiradenoma has a better prognosis.We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Atatürk Training and Research Hospital, Ankara, Turkey. sbercin@hotmail.com

ABSTRACT
Malignant eccrine spiradenomas are exceedingly rare tumors. They can arise from a preexisting eccrine spiradenoma or occur as a primary malignant tumor. Clinical features of these tumors may include a history of enlargement in a previously stable lesion. Tumor can be of low or high grade. Low-grade malignant eccrine spiradenoma has a better prognosis. We present a malignant eccrine spiradenoma arising from a preexisting eccrine spiradenoma, which has an infrequent localization between lateral edge of nose and medial canthus.

No MeSH data available.


Related in: MedlinePlus