Limits...
Tissue grafts in vitiligo surgery - past, present, and future.

Khunger N, Kathuria SD, Ramesh V - Indian J Dermatol (2009)

Bottom Line: Various grafting methods have been described including tissue grafts and cellular grafts.Stability of the disease is the most important criterion to obtain a successful outcome.The technique and followup management of the tissue grafts has been described in detail in this review.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology and STD, V.M. Medical College and Safdarjang Hospital, New Delhi, India. drniti@rediffmail.com

ABSTRACT
Vitiligo, characterized by depigmented macules is a common disorder with a high psychosocial impact, particularly in darker skins. Surgical methods become important in cases where medical therapy fails to cause repigmentation or in cases of segmental vitiligo where the response to surgery is excellent. The basic principle of surgical treatment is autologous grafting of viable melanocytes from pigmented donor skin to recipient vitiliginous areas. Various grafting methods have been described including tissue grafts and cellular grafts. Stability of the disease is the most important criterion to obtain a successful outcome. Counseling of the patient regarding the outcome is vital before surgery. The technique and followup management of the tissue grafts has been described in detail in this review.

No MeSH data available.


Related in: MedlinePlus

Infiltration anesthesia at the margins of the donor area without infiltration in the centre
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC2807155&req=5

Figure 0004: Infiltration anesthesia at the margins of the donor area without infiltration in the centre

Mentions: Though the gluteal area is a relatively difficult area to harvest, it is the most preferred site for cosmetic reasons, in case scarring occurs. However, the thigh can be used as a donor site by beginners and when larger areas of donor skin are required.[31] The arms have also been used as donor sites.[32] After surgical cleansing, the required donor area is marked with sterile marking ink or a surgical pen. A field block with 1% lignocaine is given at the margins only [Figure 4]. Infiltration anesthesia within the donor area must be avoided as it can result in an uneven surface, leading to a graft of uneven thickness. Alternatively, topical anesthesia using a mixture of lidocaine 2.5%w/w and prilocaine 2.5% w/w cream (EMLA®, Toplap®) under occlusion, for at least two hours, can be used.[33]


Tissue grafts in vitiligo surgery - past, present, and future.

Khunger N, Kathuria SD, Ramesh V - Indian J Dermatol (2009)

Infiltration anesthesia at the margins of the donor area without infiltration in the centre
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2807155&req=5

Figure 0004: Infiltration anesthesia at the margins of the donor area without infiltration in the centre
Mentions: Though the gluteal area is a relatively difficult area to harvest, it is the most preferred site for cosmetic reasons, in case scarring occurs. However, the thigh can be used as a donor site by beginners and when larger areas of donor skin are required.[31] The arms have also been used as donor sites.[32] After surgical cleansing, the required donor area is marked with sterile marking ink or a surgical pen. A field block with 1% lignocaine is given at the margins only [Figure 4]. Infiltration anesthesia within the donor area must be avoided as it can result in an uneven surface, leading to a graft of uneven thickness. Alternatively, topical anesthesia using a mixture of lidocaine 2.5%w/w and prilocaine 2.5% w/w cream (EMLA®, Toplap®) under occlusion, for at least two hours, can be used.[33]

Bottom Line: Various grafting methods have been described including tissue grafts and cellular grafts.Stability of the disease is the most important criterion to obtain a successful outcome.The technique and followup management of the tissue grafts has been described in detail in this review.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology and STD, V.M. Medical College and Safdarjang Hospital, New Delhi, India. drniti@rediffmail.com

ABSTRACT
Vitiligo, characterized by depigmented macules is a common disorder with a high psychosocial impact, particularly in darker skins. Surgical methods become important in cases where medical therapy fails to cause repigmentation or in cases of segmental vitiligo where the response to surgery is excellent. The basic principle of surgical treatment is autologous grafting of viable melanocytes from pigmented donor skin to recipient vitiliginous areas. Various grafting methods have been described including tissue grafts and cellular grafts. Stability of the disease is the most important criterion to obtain a successful outcome. Counseling of the patient regarding the outcome is vital before surgery. The technique and followup management of the tissue grafts has been described in detail in this review.

No MeSH data available.


Related in: MedlinePlus