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Tissue grafts in vitiligo surgery - past, present, and future.

Khunger N, Kathuria SD, Ramesh V - Indian J Dermatol (2009)

Bottom Line: Various grafting methods have been described including tissue grafts and cellular grafts.Stability of the disease is the most important criterion to obtain a successful outcome.The technique and followup management of the tissue grafts has been described in detail in this review.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology and STD, V.M. Medical College and Safdarjang Hospital, New Delhi, India. drniti@rediffmail.com

ABSTRACT
Vitiligo, characterized by depigmented macules is a common disorder with a high psychosocial impact, particularly in darker skins. Surgical methods become important in cases where medical therapy fails to cause repigmentation or in cases of segmental vitiligo where the response to surgery is excellent. The basic principle of surgical treatment is autologous grafting of viable melanocytes from pigmented donor skin to recipient vitiliginous areas. Various grafting methods have been described including tissue grafts and cellular grafts. Stability of the disease is the most important criterion to obtain a successful outcome. Counseling of the patient regarding the outcome is vital before surgery. The technique and followup management of the tissue grafts has been described in detail in this review.

No MeSH data available.


Related in: MedlinePlus

Raising suction blisters by the syringe method
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Figure 0001: Raising suction blisters by the syringe method

Mentions: Blisters may be raised using syringes[20] or suction pump and suction cups[21] or a negative pressure cutaneous suction chamber system.[22] Using syringes to raise blisters is the most commonly employed method. The bases of syringes of sizes 10 ml and 20 ml are coated with vaseline and are applied on the donor site [Figure 1]. Approximately 20ml to 30ml of air is aspirated using a 50ml syringe and a three-way-cannula. Larger syringes (>20ml) take a longer time to generate a blister, and smaller syringes (<10ml) provide blisters that are difficult to handle. It usually takes 1.5 to 2.5 hours for the development of blisters [Figure 2]. A single unilocular non-hemorrhagic blister is the best result. In case of smaller blisters, one can either increase the negative pressure in the syringe by another 5ml or intradermally inject saline into the blister to expand it.[23]


Tissue grafts in vitiligo surgery - past, present, and future.

Khunger N, Kathuria SD, Ramesh V - Indian J Dermatol (2009)

Raising suction blisters by the syringe method
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2807155&req=5

Figure 0001: Raising suction blisters by the syringe method
Mentions: Blisters may be raised using syringes[20] or suction pump and suction cups[21] or a negative pressure cutaneous suction chamber system.[22] Using syringes to raise blisters is the most commonly employed method. The bases of syringes of sizes 10 ml and 20 ml are coated with vaseline and are applied on the donor site [Figure 1]. Approximately 20ml to 30ml of air is aspirated using a 50ml syringe and a three-way-cannula. Larger syringes (>20ml) take a longer time to generate a blister, and smaller syringes (<10ml) provide blisters that are difficult to handle. It usually takes 1.5 to 2.5 hours for the development of blisters [Figure 2]. A single unilocular non-hemorrhagic blister is the best result. In case of smaller blisters, one can either increase the negative pressure in the syringe by another 5ml or intradermally inject saline into the blister to expand it.[23]

Bottom Line: Various grafting methods have been described including tissue grafts and cellular grafts.Stability of the disease is the most important criterion to obtain a successful outcome.The technique and followup management of the tissue grafts has been described in detail in this review.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology and STD, V.M. Medical College and Safdarjang Hospital, New Delhi, India. drniti@rediffmail.com

ABSTRACT
Vitiligo, characterized by depigmented macules is a common disorder with a high psychosocial impact, particularly in darker skins. Surgical methods become important in cases where medical therapy fails to cause repigmentation or in cases of segmental vitiligo where the response to surgery is excellent. The basic principle of surgical treatment is autologous grafting of viable melanocytes from pigmented donor skin to recipient vitiliginous areas. Various grafting methods have been described including tissue grafts and cellular grafts. Stability of the disease is the most important criterion to obtain a successful outcome. Counseling of the patient regarding the outcome is vital before surgery. The technique and followup management of the tissue grafts has been described in detail in this review.

No MeSH data available.


Related in: MedlinePlus