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Monte Carlo simulation studies on scintillation detectors and image reconstruction of brain-phantom tumors in TOFPET.

Mondal NN - J Med Phys (2009)

Bottom Line: This study presents Monte Carlo Simulation (MCS) results of detection efficiencies, spatial resolutions and resolving powers of a time-of-flight (TOF) PET detector systems.The results of MCS based on GEANT show that spatial resolution, detection efficiency and resolving power of LSO are better than those of BaF(2) and LaBr(3), although it possesses inferior time and energy resolutions.Validation is a momentous step to ensure that this imaging method fulfills all purposes of motivation discussed by reconstructing images of two tumors in a brain phantom.

View Article: PubMed Central - PubMed

Affiliation: High Energy Physics Group, 1/AF Bidhannagar, Kolkata 700064, India. E-mail: nagendra.mondal@veccal.ernet.in.

ABSTRACT
This study presents Monte Carlo Simulation (MCS) results of detection efficiencies, spatial resolutions and resolving powers of a time-of-flight (TOF) PET detector systems. Cerium activated Lutetium Oxyorthosilicate (Lu(2)SiO(5): Ce in short LSO), Barium Fluoride (BaF(2)) and BriLanCe 380 (Cerium doped Lanthanum tri-Bromide, in short LaBr(3)) scintillation crystals are studied in view of their good time and energy resolutions and shorter decay times. The results of MCS based on GEANT show that spatial resolution, detection efficiency and resolving power of LSO are better than those of BaF(2) and LaBr(3), although it possesses inferior time and energy resolutions. Instead of the conventional position reconstruction method, newly established image reconstruction (talked about in the previous work) method is applied to produce high-tech images. Validation is a momentous step to ensure that this imaging method fulfills all purposes of motivation discussed by reconstructing images of two tumors in a brain phantom.

No MeSH data available.


Related in: MedlinePlus

Decay scheme of 189F (a), and molecular formula of FDG (C6H11FO5) (b).[11]
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Figure 0003: Decay scheme of 189F (a), and molecular formula of FDG (C6H11FO5) (b).[11]

Mentions: A typical dose of FDG used in an oncological scan is 200 - 400 MBq for an adult human and very useful for brain tumor identification. Biochemical processes can be traced precisely and a patient can be diagnosed several times in a day due to its shorter half-life. The decay scheme of 189F and structural formula of FDG are given in Figure 3.


Monte Carlo simulation studies on scintillation detectors and image reconstruction of brain-phantom tumors in TOFPET.

Mondal NN - J Med Phys (2009)

Decay scheme of 189F (a), and molecular formula of FDG (C6H11FO5) (b).[11]
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2807143&req=5

Figure 0003: Decay scheme of 189F (a), and molecular formula of FDG (C6H11FO5) (b).[11]
Mentions: A typical dose of FDG used in an oncological scan is 200 - 400 MBq for an adult human and very useful for brain tumor identification. Biochemical processes can be traced precisely and a patient can be diagnosed several times in a day due to its shorter half-life. The decay scheme of 189F and structural formula of FDG are given in Figure 3.

Bottom Line: This study presents Monte Carlo Simulation (MCS) results of detection efficiencies, spatial resolutions and resolving powers of a time-of-flight (TOF) PET detector systems.The results of MCS based on GEANT show that spatial resolution, detection efficiency and resolving power of LSO are better than those of BaF(2) and LaBr(3), although it possesses inferior time and energy resolutions.Validation is a momentous step to ensure that this imaging method fulfills all purposes of motivation discussed by reconstructing images of two tumors in a brain phantom.

View Article: PubMed Central - PubMed

Affiliation: High Energy Physics Group, 1/AF Bidhannagar, Kolkata 700064, India. E-mail: nagendra.mondal@veccal.ernet.in.

ABSTRACT
This study presents Monte Carlo Simulation (MCS) results of detection efficiencies, spatial resolutions and resolving powers of a time-of-flight (TOF) PET detector systems. Cerium activated Lutetium Oxyorthosilicate (Lu(2)SiO(5): Ce in short LSO), Barium Fluoride (BaF(2)) and BriLanCe 380 (Cerium doped Lanthanum tri-Bromide, in short LaBr(3)) scintillation crystals are studied in view of their good time and energy resolutions and shorter decay times. The results of MCS based on GEANT show that spatial resolution, detection efficiency and resolving power of LSO are better than those of BaF(2) and LaBr(3), although it possesses inferior time and energy resolutions. Instead of the conventional position reconstruction method, newly established image reconstruction (talked about in the previous work) method is applied to produce high-tech images. Validation is a momentous step to ensure that this imaging method fulfills all purposes of motivation discussed by reconstructing images of two tumors in a brain phantom.

No MeSH data available.


Related in: MedlinePlus