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Sarcoidosis with photosensitive lesions: a rare variant.

Gangopadhyay A, Das JK, Sengupta S - Indian J Dermatol (2009)

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The final diagnosis was cutaneous sarcoidosis with photosensitive lesions... Typical sarcoid granuloma was seen in histopathology [Figure 8, Figure 9]... Other relevant tests done were also normal... Sunscreens, topical steroids and hydroxychloroquine sulphate (200mg EOD) produced significant improvement within three months [Figure 10]... Sarcoid lesions mimicking lupus have been reported before... Case 2 closely resembled granuloma annulare, but photosensitivity, negative Mantoux test, classical naked granuloma without any necrobiosis and raised SACE helped to exclude it... In a recently published study of 23 Indian sarcoid patients, photosensitive skin lesions have not been documented... The preferential distribution of skin lesions in photo-exposed areas and the significant clearing with hydroxychloroquine sulphate are the two aspects that make the cases special... A French article describes a Tunisian woman with papular erythema of the face, unresponsive to topical steroids... She was histologically diagnosed to be a case of cutaneous sarcoid and the authors opined that photo-induced sarcoid is a distinct entity... Our cases further strengthen the view.

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Papular skin lesions on upper chest in Case 2
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Figure 0007: Papular skin lesions on upper chest in Case 2

Mentions: A 37-year-old businessman suffered from asymptomatic skin colored papules in the upper chest for six months [Figure 7]. Sun exposure made them pruritic and erythematous. The rest of the dermatologic and systemic examination was normal. Investigations showed raised ESR (45 mm), negative Mantoux test and normal chest X-Ray. Typical sarcoid granuloma was seen in histopathology [Figure 8, Figure 9]. SACE was raised (90U/L) and serum calcium was normal. Other relevant tests done were also normal. Sunscreens, topical steroids and hydroxychloroquine sulphate (200mg EOD) produced significant improvement within three months [Figure 10].


Sarcoidosis with photosensitive lesions: a rare variant.

Gangopadhyay A, Das JK, Sengupta S - Indian J Dermatol (2009)

Papular skin lesions on upper chest in Case 2
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2800887&req=5

Figure 0007: Papular skin lesions on upper chest in Case 2
Mentions: A 37-year-old businessman suffered from asymptomatic skin colored papules in the upper chest for six months [Figure 7]. Sun exposure made them pruritic and erythematous. The rest of the dermatologic and systemic examination was normal. Investigations showed raised ESR (45 mm), negative Mantoux test and normal chest X-Ray. Typical sarcoid granuloma was seen in histopathology [Figure 8, Figure 9]. SACE was raised (90U/L) and serum calcium was normal. Other relevant tests done were also normal. Sunscreens, topical steroids and hydroxychloroquine sulphate (200mg EOD) produced significant improvement within three months [Figure 10].

View Article: PubMed Central - PubMed

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

The final diagnosis was cutaneous sarcoidosis with photosensitive lesions... Typical sarcoid granuloma was seen in histopathology [Figure 8, Figure 9]... Other relevant tests done were also normal... Sunscreens, topical steroids and hydroxychloroquine sulphate (200mg EOD) produced significant improvement within three months [Figure 10]... Sarcoid lesions mimicking lupus have been reported before... Case 2 closely resembled granuloma annulare, but photosensitivity, negative Mantoux test, classical naked granuloma without any necrobiosis and raised SACE helped to exclude it... In a recently published study of 23 Indian sarcoid patients, photosensitive skin lesions have not been documented... The preferential distribution of skin lesions in photo-exposed areas and the significant clearing with hydroxychloroquine sulphate are the two aspects that make the cases special... A French article describes a Tunisian woman with papular erythema of the face, unresponsive to topical steroids... She was histologically diagnosed to be a case of cutaneous sarcoid and the authors opined that photo-induced sarcoid is a distinct entity... Our cases further strengthen the view.

No MeSH data available.


Related in: MedlinePlus