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Multiple smooth muscle hamartoma: case report and review of the literature.

Haydeh G, Massoud A, Pedram N - Indian J Dermatol (2009)

Bottom Line: Multiple SMHs have rarely been reported in the literature.We describe the case of a seven-month-old girl with multiple SMHs located over the back and arm areas.She had no cerebral or skeletal abnormalities and her growth and development were normal.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Tehran University of Medical Sciences, Razi Hospital, Tehran, Iran.

ABSTRACT
Smooth muscle hamartoma (SMH) is a proliferative disorder of cells originating from muscle cells. It is a benign tumoral mass that usually presents as a single congenital skin-colored and hypertrichotic plaque involving the trunk and extremities. Multiple SMHs have rarely been reported in the literature. We describe the case of a seven-month-old girl with multiple SMHs located over the back and arm areas. The diagnosis was confirmed by biopsy and immunohistochemical (IHC) staining. She had no cerebral or skeletal abnormalities and her growth and development were normal.

No MeSH data available.


Related in: MedlinePlus

SMH IHC staining (magniÞ cation ×400)
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Figure 0006: SMH IHC staining (magniÞ cation ×400)

Mentions: Histopathologically, there were masses of spindle smooth muscle cells, distantly arranged in the superficial and deep dermis [Figure 4]. Immunohistochemical (IHC) stain with smooth muscle actin confirmed a diagnosis of SMH [Figure 5, Figure 6] and the nature of the proliferation. An MRI (magnetic resonance imaging) and CT (computerized tomography) scan showed no neurological deficit and abnormality in the central nervous system (CNS). Electromyography (EMG) and nerve conduction velocity (NCV) findings were also normal. The rest of the clinical examination was normal.


Multiple smooth muscle hamartoma: case report and review of the literature.

Haydeh G, Massoud A, Pedram N - Indian J Dermatol (2009)

SMH IHC staining (magniÞ cation ×400)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2800877&req=5

Figure 0006: SMH IHC staining (magniÞ cation ×400)
Mentions: Histopathologically, there were masses of spindle smooth muscle cells, distantly arranged in the superficial and deep dermis [Figure 4]. Immunohistochemical (IHC) stain with smooth muscle actin confirmed a diagnosis of SMH [Figure 5, Figure 6] and the nature of the proliferation. An MRI (magnetic resonance imaging) and CT (computerized tomography) scan showed no neurological deficit and abnormality in the central nervous system (CNS). Electromyography (EMG) and nerve conduction velocity (NCV) findings were also normal. The rest of the clinical examination was normal.

Bottom Line: Multiple SMHs have rarely been reported in the literature.We describe the case of a seven-month-old girl with multiple SMHs located over the back and arm areas.She had no cerebral or skeletal abnormalities and her growth and development were normal.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Tehran University of Medical Sciences, Razi Hospital, Tehran, Iran.

ABSTRACT
Smooth muscle hamartoma (SMH) is a proliferative disorder of cells originating from muscle cells. It is a benign tumoral mass that usually presents as a single congenital skin-colored and hypertrichotic plaque involving the trunk and extremities. Multiple SMHs have rarely been reported in the literature. We describe the case of a seven-month-old girl with multiple SMHs located over the back and arm areas. The diagnosis was confirmed by biopsy and immunohistochemical (IHC) staining. She had no cerebral or skeletal abnormalities and her growth and development were normal.

No MeSH data available.


Related in: MedlinePlus