Limits...
Central corneal thickness in subjects with glaucoma and in normal individuals (with or without pseudoexfoliation syndrome).

Kitsos G, Gartzios C, Asproudis I, Bagli E - Clin Ophthalmol (2009)

Bottom Line: CCT in PEXG eyes (526.00 +/- 34.30 mum) was significantly thinner compared to POAG eyes (549.36 +/- 39.3 mum) (P = 0.027) and normal control eyes with (550.64 +/- 39.0 mum) or without PXS (547.36 +/- 33.1 mum), (P = 0.039 and 0.048 respectively).No statistically significant difference was found comparing CCT values of POAG eyes to control group eyes.The evaluation of CCT is necessary in all patients with glaucoma and especially in those with PEXG due to the thinner cornea and the risk of underestimation of intraocular pressure.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, University of Ioannina, Ioannina, Greece.

ABSTRACT

Objective: The evaluation of central corneal thickness (CCT) in subjects with pesudoexfoliation glaucoma (PEXG), primary open-angle glaucoma (POAG), and in normotensive individuals with or without pseudoexfoliation syndrome (PXS).

Study design/patients and methods: CCT was evaluated with ultrasound pachymetry in a total of 179 individuals: 32 had bilateral PEXG, 55 had bilateral POAG, 35 had PXS, and 57 were healthy individuals without PXS.

Results: CCT in PEXG eyes (526.00 +/- 34.30 mum) was significantly thinner compared to POAG eyes (549.36 +/- 39.3 mum) (P = 0.027) and normal control eyes with (550.64 +/- 39.0 mum) or without PXS (547.36 +/- 33.1 mum), (P = 0.039 and 0.048 respectively). No statistically significant difference was found comparing CCT values of POAG eyes to control group eyes.

Conclusion: The evaluation of CCT is necessary in all patients with glaucoma and especially in those with PEXG due to the thinner cornea and the risk of underestimation of intraocular pressure.

No MeSH data available.


Related in: MedlinePlus

Central corneal thickness (CCT) in glaucoma subgroups and control group. The CCT values were measured with the PACLINE OPTICON 2000 S.p.A. The mean CCT with error bars in the different glaucoma and control groups are plotted.Note: *Statistically significant at P = 0.021 (<0.05) ANOVA test.Abbreviations: POAG, primary open-angle glaucoma; PEXG, pseudoexfoliation glaucoma; CTL-PXS, control group with pseudoexfoliation syndrome; CTL, control group without pseudoexfoliation syndrome; CI, confidence interval.
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC2770864&req=5

f1-opth-3-537: Central corneal thickness (CCT) in glaucoma subgroups and control group. The CCT values were measured with the PACLINE OPTICON 2000 S.p.A. The mean CCT with error bars in the different glaucoma and control groups are plotted.Note: *Statistically significant at P = 0.021 (<0.05) ANOVA test.Abbreviations: POAG, primary open-angle glaucoma; PEXG, pseudoexfoliation glaucoma; CTL-PXS, control group with pseudoexfoliation syndrome; CTL, control group without pseudoexfoliation syndrome; CI, confidence interval.

Mentions: Regarding CCT, our results showed the following mean measurements in the groups under study: 526.00 ± 34.30 μm in eyes with PEXG, 549.36 ± 39.3 μm in eyes with POAG, 550.64 ± 39.0 μm in the control group with PXS, and 547.36 ± 33.1 in the control group without PXS (Table 2, Figure 1). No statistically significant difference was found when comparing CCT values of subjects with POAG to control group with or without PXS (one-way ANOVA test, P = 0.999 and 0.991, respectively). However, subjects with PEXG had statistically significant thinner cornea compared to all the other groups (one-way ANOVA test: POAG group, P = 0.027; control group with PXS, P = 0.039; and control without PXS, P = 0.048). Finally CCT was similar between control groups with or without pseudoexfoliation (one-way ANOVA test, P = 0.992).


Central corneal thickness in subjects with glaucoma and in normal individuals (with or without pseudoexfoliation syndrome).

Kitsos G, Gartzios C, Asproudis I, Bagli E - Clin Ophthalmol (2009)

Central corneal thickness (CCT) in glaucoma subgroups and control group. The CCT values were measured with the PACLINE OPTICON 2000 S.p.A. The mean CCT with error bars in the different glaucoma and control groups are plotted.Note: *Statistically significant at P = 0.021 (<0.05) ANOVA test.Abbreviations: POAG, primary open-angle glaucoma; PEXG, pseudoexfoliation glaucoma; CTL-PXS, control group with pseudoexfoliation syndrome; CTL, control group without pseudoexfoliation syndrome; CI, confidence interval.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2770864&req=5

f1-opth-3-537: Central corneal thickness (CCT) in glaucoma subgroups and control group. The CCT values were measured with the PACLINE OPTICON 2000 S.p.A. The mean CCT with error bars in the different glaucoma and control groups are plotted.Note: *Statistically significant at P = 0.021 (<0.05) ANOVA test.Abbreviations: POAG, primary open-angle glaucoma; PEXG, pseudoexfoliation glaucoma; CTL-PXS, control group with pseudoexfoliation syndrome; CTL, control group without pseudoexfoliation syndrome; CI, confidence interval.
Mentions: Regarding CCT, our results showed the following mean measurements in the groups under study: 526.00 ± 34.30 μm in eyes with PEXG, 549.36 ± 39.3 μm in eyes with POAG, 550.64 ± 39.0 μm in the control group with PXS, and 547.36 ± 33.1 in the control group without PXS (Table 2, Figure 1). No statistically significant difference was found when comparing CCT values of subjects with POAG to control group with or without PXS (one-way ANOVA test, P = 0.999 and 0.991, respectively). However, subjects with PEXG had statistically significant thinner cornea compared to all the other groups (one-way ANOVA test: POAG group, P = 0.027; control group with PXS, P = 0.039; and control without PXS, P = 0.048). Finally CCT was similar between control groups with or without pseudoexfoliation (one-way ANOVA test, P = 0.992).

Bottom Line: CCT in PEXG eyes (526.00 +/- 34.30 mum) was significantly thinner compared to POAG eyes (549.36 +/- 39.3 mum) (P = 0.027) and normal control eyes with (550.64 +/- 39.0 mum) or without PXS (547.36 +/- 33.1 mum), (P = 0.039 and 0.048 respectively).No statistically significant difference was found comparing CCT values of POAG eyes to control group eyes.The evaluation of CCT is necessary in all patients with glaucoma and especially in those with PEXG due to the thinner cornea and the risk of underestimation of intraocular pressure.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, University of Ioannina, Ioannina, Greece.

ABSTRACT

Objective: The evaluation of central corneal thickness (CCT) in subjects with pesudoexfoliation glaucoma (PEXG), primary open-angle glaucoma (POAG), and in normotensive individuals with or without pseudoexfoliation syndrome (PXS).

Study design/patients and methods: CCT was evaluated with ultrasound pachymetry in a total of 179 individuals: 32 had bilateral PEXG, 55 had bilateral POAG, 35 had PXS, and 57 were healthy individuals without PXS.

Results: CCT in PEXG eyes (526.00 +/- 34.30 mum) was significantly thinner compared to POAG eyes (549.36 +/- 39.3 mum) (P = 0.027) and normal control eyes with (550.64 +/- 39.0 mum) or without PXS (547.36 +/- 33.1 mum), (P = 0.039 and 0.048 respectively). No statistically significant difference was found comparing CCT values of POAG eyes to control group eyes.

Conclusion: The evaluation of CCT is necessary in all patients with glaucoma and especially in those with PEXG due to the thinner cornea and the risk of underestimation of intraocular pressure.

No MeSH data available.


Related in: MedlinePlus