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Typical and atypical manifestations of intrathoracic sarcoidosis.

Park HJ, Jung JI, Chung MH, Song SW, Kim HL, Baik JH, Han DH, Kim KJ, Lee KY - Korean J Radiol (2009 Nov-Dec)

Bottom Line: The findings include symmetric, bilateral hilar and paratracheal lymphadenopathy, with or without concomitant parenchymal abnormalities (multiple small nodules in a peribronchovascular distribution along with irregular thickening of the interstitium).However, in 25% to 30% of cases, the radiological findings are atypical and unfamiliar to most radiologists, which cause difficulty for making a correct diagnosis.We have collected cases with unusual radiological findings associated with pulmonary sarcoidosis (unilateral or asymmetric lymphadenopathy, necrosis or cavitation, large opacity, ground glass opacity, an airway abnormality and pleural involvement) and describe the typical forms of the disorder as well.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, St. Vincent's Hospital, The Catholic University of Korea, Kyunggi-do 442-723, Korea.

ABSTRACT
Sarcoidosis is a systemic disorder of unknown cause that is characterized by the presence of noncaseating granulomas. The radiological findings associated with sarcoidosis have been well described. The findings include symmetric, bilateral hilar and paratracheal lymphadenopathy, with or without concomitant parenchymal abnormalities (multiple small nodules in a peribronchovascular distribution along with irregular thickening of the interstitium). However, in 25% to 30% of cases, the radiological findings are atypical and unfamiliar to most radiologists, which cause difficulty for making a correct diagnosis. Many atypical forms of intrathoracic sarcoidosis have been described sporadically. We have collected cases with unusual radiological findings associated with pulmonary sarcoidosis (unilateral or asymmetric lymphadenopathy, necrosis or cavitation, large opacity, ground glass opacity, an airway abnormality and pleural involvement) and describe the typical forms of the disorder as well. The understanding of a wide range of the radiological manifestations of sarcoidosis will be very helpful for making a proper diagnosis.

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Related in: MedlinePlus

Node calcification in sarcoidosis is shown.Axial CT scan shows typical eggshell calcification in both hilar and peribronchial nodes (arrows). Presence of node calcification suggests chronic condition.
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Figure 2: Node calcification in sarcoidosis is shown.Axial CT scan shows typical eggshell calcification in both hilar and peribronchial nodes (arrows). Presence of node calcification suggests chronic condition.

Mentions: Lymph node calcification is visible in 25% to 50% of cases and may have an amorphous, stippled or eggshell appearance. Node calcification is closely related to the duration of the disease and suggests a chronic condition, a finding similar to other chronic granulomatous diseases (3, 5) (Fig. 2).


Typical and atypical manifestations of intrathoracic sarcoidosis.

Park HJ, Jung JI, Chung MH, Song SW, Kim HL, Baik JH, Han DH, Kim KJ, Lee KY - Korean J Radiol (2009 Nov-Dec)

Node calcification in sarcoidosis is shown.Axial CT scan shows typical eggshell calcification in both hilar and peribronchial nodes (arrows). Presence of node calcification suggests chronic condition.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2770817&req=5

Figure 2: Node calcification in sarcoidosis is shown.Axial CT scan shows typical eggshell calcification in both hilar and peribronchial nodes (arrows). Presence of node calcification suggests chronic condition.
Mentions: Lymph node calcification is visible in 25% to 50% of cases and may have an amorphous, stippled or eggshell appearance. Node calcification is closely related to the duration of the disease and suggests a chronic condition, a finding similar to other chronic granulomatous diseases (3, 5) (Fig. 2).

Bottom Line: The findings include symmetric, bilateral hilar and paratracheal lymphadenopathy, with or without concomitant parenchymal abnormalities (multiple small nodules in a peribronchovascular distribution along with irregular thickening of the interstitium).However, in 25% to 30% of cases, the radiological findings are atypical and unfamiliar to most radiologists, which cause difficulty for making a correct diagnosis.We have collected cases with unusual radiological findings associated with pulmonary sarcoidosis (unilateral or asymmetric lymphadenopathy, necrosis or cavitation, large opacity, ground glass opacity, an airway abnormality and pleural involvement) and describe the typical forms of the disorder as well.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, St. Vincent's Hospital, The Catholic University of Korea, Kyunggi-do 442-723, Korea.

ABSTRACT
Sarcoidosis is a systemic disorder of unknown cause that is characterized by the presence of noncaseating granulomas. The radiological findings associated with sarcoidosis have been well described. The findings include symmetric, bilateral hilar and paratracheal lymphadenopathy, with or without concomitant parenchymal abnormalities (multiple small nodules in a peribronchovascular distribution along with irregular thickening of the interstitium). However, in 25% to 30% of cases, the radiological findings are atypical and unfamiliar to most radiologists, which cause difficulty for making a correct diagnosis. Many atypical forms of intrathoracic sarcoidosis have been described sporadically. We have collected cases with unusual radiological findings associated with pulmonary sarcoidosis (unilateral or asymmetric lymphadenopathy, necrosis or cavitation, large opacity, ground glass opacity, an airway abnormality and pleural involvement) and describe the typical forms of the disorder as well. The understanding of a wide range of the radiological manifestations of sarcoidosis will be very helpful for making a proper diagnosis.

Show MeSH
Related in: MedlinePlus