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Measurement of end-expiratory lung volume in intubated children without interruption of mechanical ventilation.

Bikker IG, Scohy TV - Intensive Care Med (2009)

Bottom Line: Also, there was good agreement between duplicate measurements, bias +/- SD: -0.3% (-1.5 mL) +/- 5.9% (19.2 mL).EELV correlated with age (p < 0.001, r = 0.92, R (2) = 0.78), body weight (p < 0.001, r = 0.91, R (2) = 0.82) and height (p < 0.001, r = 0.94, R (2) = 0.75).This ICU ventilator with an in-built nitrogen washout/washin EELV technique can measure EELV with precision, and can easily be used for mechanically ventilated pediatric patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Intensive Care Medicine, Erasmus MC, Room H602, 's-Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.

ABSTRACT

Purpose: Monitoring end-expiratory lung volume (EELV) is a valuable tool to optimize respiratory settings that could be of particular importance in mechanically ventilated pediatric patients. We evaluated the feasibility and precision of an intensive care unit (ICU) ventilator with an in-built nitrogen washout/washin technique in mechanically ventilated pediatric patients.

Methods: Duplicate EELV measurements were performed in 30 patients between 5 kg and 43 kg after cardiac surgery (age, median + range: 26, 3-141 months). All measurements were taken during pressure-controlled ventilation at 0 cm H(2)O of positive end-expiratory pressure (PEEP).

Results: Linear regression between duplicate measurements was excellent (R (2) = 0.99). Also, there was good agreement between duplicate measurements, bias +/- SD: -0.3% (-1.5 mL) +/- 5.9% (19.2 mL). Mean EELV +/- SD was 19.6 +/- 5.1 mL/kg at 0 cm H(2)O PEEP. EELV correlated with age (p < 0.001, r = 0.92, R (2) = 0.78), body weight (p < 0.001, r = 0.91, R (2) = 0.82) and height (p < 0.001, r = 0.94, R (2) = 0.75).

Conclusion: This ICU ventilator with an in-built nitrogen washout/washin EELV technique can measure EELV with precision, and can easily be used for mechanically ventilated pediatric patients.

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Related in: MedlinePlus

Relation between EELV (average of duplicates) and height or body weight. Measurements were performed in the supine position at 0 cm H2O PEEP in mechanically ventilated pediatric patients after cardiac surgery. The lines represent non-linear regression equations from non-intubated children, Stocks and Quanjer [26] and intubated children at 0 cm H2O PEEP, Thorsteinsson et al. [23] and Bar-Yishay et al. [21]
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Fig2: Relation between EELV (average of duplicates) and height or body weight. Measurements were performed in the supine position at 0 cm H2O PEEP in mechanically ventilated pediatric patients after cardiac surgery. The lines represent non-linear regression equations from non-intubated children, Stocks and Quanjer [26] and intubated children at 0 cm H2O PEEP, Thorsteinsson et al. [23] and Bar-Yishay et al. [21]

Mentions: Mean EELV ± SD was 19.6 ± 5.1 mL/kg at a PEEP level of 0 cm H2O. Figure 2 shows the relation between EELV and patient characteristics. EELV was highly correlated with age (p < 0.001, r = 0.92, R2 = 0.78), body weight (p < 0.001, r = 0.91, R2 = 0.82) and height (p < 0.001, r = 0.94, R2 = 0.75).Fig. 2


Measurement of end-expiratory lung volume in intubated children without interruption of mechanical ventilation.

Bikker IG, Scohy TV - Intensive Care Med (2009)

Relation between EELV (average of duplicates) and height or body weight. Measurements were performed in the supine position at 0 cm H2O PEEP in mechanically ventilated pediatric patients after cardiac surgery. The lines represent non-linear regression equations from non-intubated children, Stocks and Quanjer [26] and intubated children at 0 cm H2O PEEP, Thorsteinsson et al. [23] and Bar-Yishay et al. [21]
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2749178&req=5

Fig2: Relation between EELV (average of duplicates) and height or body weight. Measurements were performed in the supine position at 0 cm H2O PEEP in mechanically ventilated pediatric patients after cardiac surgery. The lines represent non-linear regression equations from non-intubated children, Stocks and Quanjer [26] and intubated children at 0 cm H2O PEEP, Thorsteinsson et al. [23] and Bar-Yishay et al. [21]
Mentions: Mean EELV ± SD was 19.6 ± 5.1 mL/kg at a PEEP level of 0 cm H2O. Figure 2 shows the relation between EELV and patient characteristics. EELV was highly correlated with age (p < 0.001, r = 0.92, R2 = 0.78), body weight (p < 0.001, r = 0.91, R2 = 0.82) and height (p < 0.001, r = 0.94, R2 = 0.75).Fig. 2

Bottom Line: Also, there was good agreement between duplicate measurements, bias +/- SD: -0.3% (-1.5 mL) +/- 5.9% (19.2 mL).EELV correlated with age (p < 0.001, r = 0.92, R (2) = 0.78), body weight (p < 0.001, r = 0.91, R (2) = 0.82) and height (p < 0.001, r = 0.94, R (2) = 0.75).This ICU ventilator with an in-built nitrogen washout/washin EELV technique can measure EELV with precision, and can easily be used for mechanically ventilated pediatric patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Intensive Care Medicine, Erasmus MC, Room H602, 's-Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.

ABSTRACT

Purpose: Monitoring end-expiratory lung volume (EELV) is a valuable tool to optimize respiratory settings that could be of particular importance in mechanically ventilated pediatric patients. We evaluated the feasibility and precision of an intensive care unit (ICU) ventilator with an in-built nitrogen washout/washin technique in mechanically ventilated pediatric patients.

Methods: Duplicate EELV measurements were performed in 30 patients between 5 kg and 43 kg after cardiac surgery (age, median + range: 26, 3-141 months). All measurements were taken during pressure-controlled ventilation at 0 cm H(2)O of positive end-expiratory pressure (PEEP).

Results: Linear regression between duplicate measurements was excellent (R (2) = 0.99). Also, there was good agreement between duplicate measurements, bias +/- SD: -0.3% (-1.5 mL) +/- 5.9% (19.2 mL). Mean EELV +/- SD was 19.6 +/- 5.1 mL/kg at 0 cm H(2)O PEEP. EELV correlated with age (p < 0.001, r = 0.92, R (2) = 0.78), body weight (p < 0.001, r = 0.91, R (2) = 0.82) and height (p < 0.001, r = 0.94, R (2) = 0.75).

Conclusion: This ICU ventilator with an in-built nitrogen washout/washin EELV technique can measure EELV with precision, and can easily be used for mechanically ventilated pediatric patients.

Show MeSH
Related in: MedlinePlus