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Measurement of end-expiratory lung volume in intubated children without interruption of mechanical ventilation.

Bikker IG, Scohy TV - Intensive Care Med (2009)

Bottom Line: Also, there was good agreement between duplicate measurements, bias +/- SD: -0.3% (-1.5 mL) +/- 5.9% (19.2 mL).EELV correlated with age (p < 0.001, r = 0.92, R (2) = 0.78), body weight (p < 0.001, r = 0.91, R (2) = 0.82) and height (p < 0.001, r = 0.94, R (2) = 0.75).This ICU ventilator with an in-built nitrogen washout/washin EELV technique can measure EELV with precision, and can easily be used for mechanically ventilated pediatric patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Intensive Care Medicine, Erasmus MC, Room H602, 's-Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.

ABSTRACT

Purpose: Monitoring end-expiratory lung volume (EELV) is a valuable tool to optimize respiratory settings that could be of particular importance in mechanically ventilated pediatric patients. We evaluated the feasibility and precision of an intensive care unit (ICU) ventilator with an in-built nitrogen washout/washin technique in mechanically ventilated pediatric patients.

Methods: Duplicate EELV measurements were performed in 30 patients between 5 kg and 43 kg after cardiac surgery (age, median + range: 26, 3-141 months). All measurements were taken during pressure-controlled ventilation at 0 cm H(2)O of positive end-expiratory pressure (PEEP).

Results: Linear regression between duplicate measurements was excellent (R (2) = 0.99). Also, there was good agreement between duplicate measurements, bias +/- SD: -0.3% (-1.5 mL) +/- 5.9% (19.2 mL). Mean EELV +/- SD was 19.6 +/- 5.1 mL/kg at 0 cm H(2)O PEEP. EELV correlated with age (p < 0.001, r = 0.92, R (2) = 0.78), body weight (p < 0.001, r = 0.91, R (2) = 0.82) and height (p < 0.001, r = 0.94, R (2) = 0.75).

Conclusion: This ICU ventilator with an in-built nitrogen washout/washin EELV technique can measure EELV with precision, and can easily be used for mechanically ventilated pediatric patients.

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Bland–Altman analysis. Comparison of duplicate end-expiratory lung volume (EELV) measurements with the multibreath nitrogen washout technique. Measurements were performed in the supine position at 0 cm H2O positive end-expiratory pressure (PEEP) in mechanically ventilated pediatric patients after cardiac surgery
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Fig1: Bland–Altman analysis. Comparison of duplicate end-expiratory lung volume (EELV) measurements with the multibreath nitrogen washout technique. Measurements were performed in the supine position at 0 cm H2O positive end-expiratory pressure (PEEP) in mechanically ventilated pediatric patients after cardiac surgery

Mentions: Linear regression between duplicate EELV measurements (as average of washin/washout) measured with the nitrogen washin/washout technique was performed. Duplicate measurements were highly correlated (p < 0.001, r = 0.99, R2 = 0.99). To assess the difference between the duplicate measurements a Bland–Altmann analysis was performed (Fig. 1). Bias ± SD was −0.3% (−1.5 mL) ± 5.9% (19.2 mL).Fig. 1


Measurement of end-expiratory lung volume in intubated children without interruption of mechanical ventilation.

Bikker IG, Scohy TV - Intensive Care Med (2009)

Bland–Altman analysis. Comparison of duplicate end-expiratory lung volume (EELV) measurements with the multibreath nitrogen washout technique. Measurements were performed in the supine position at 0 cm H2O positive end-expiratory pressure (PEEP) in mechanically ventilated pediatric patients after cardiac surgery
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2749178&req=5

Fig1: Bland–Altman analysis. Comparison of duplicate end-expiratory lung volume (EELV) measurements with the multibreath nitrogen washout technique. Measurements were performed in the supine position at 0 cm H2O positive end-expiratory pressure (PEEP) in mechanically ventilated pediatric patients after cardiac surgery
Mentions: Linear regression between duplicate EELV measurements (as average of washin/washout) measured with the nitrogen washin/washout technique was performed. Duplicate measurements were highly correlated (p < 0.001, r = 0.99, R2 = 0.99). To assess the difference between the duplicate measurements a Bland–Altmann analysis was performed (Fig. 1). Bias ± SD was −0.3% (−1.5 mL) ± 5.9% (19.2 mL).Fig. 1

Bottom Line: Also, there was good agreement between duplicate measurements, bias +/- SD: -0.3% (-1.5 mL) +/- 5.9% (19.2 mL).EELV correlated with age (p < 0.001, r = 0.92, R (2) = 0.78), body weight (p < 0.001, r = 0.91, R (2) = 0.82) and height (p < 0.001, r = 0.94, R (2) = 0.75).This ICU ventilator with an in-built nitrogen washout/washin EELV technique can measure EELV with precision, and can easily be used for mechanically ventilated pediatric patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Intensive Care Medicine, Erasmus MC, Room H602, 's-Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.

ABSTRACT

Purpose: Monitoring end-expiratory lung volume (EELV) is a valuable tool to optimize respiratory settings that could be of particular importance in mechanically ventilated pediatric patients. We evaluated the feasibility and precision of an intensive care unit (ICU) ventilator with an in-built nitrogen washout/washin technique in mechanically ventilated pediatric patients.

Methods: Duplicate EELV measurements were performed in 30 patients between 5 kg and 43 kg after cardiac surgery (age, median + range: 26, 3-141 months). All measurements were taken during pressure-controlled ventilation at 0 cm H(2)O of positive end-expiratory pressure (PEEP).

Results: Linear regression between duplicate measurements was excellent (R (2) = 0.99). Also, there was good agreement between duplicate measurements, bias +/- SD: -0.3% (-1.5 mL) +/- 5.9% (19.2 mL). Mean EELV +/- SD was 19.6 +/- 5.1 mL/kg at 0 cm H(2)O PEEP. EELV correlated with age (p < 0.001, r = 0.92, R (2) = 0.78), body weight (p < 0.001, r = 0.91, R (2) = 0.82) and height (p < 0.001, r = 0.94, R (2) = 0.75).

Conclusion: This ICU ventilator with an in-built nitrogen washout/washin EELV technique can measure EELV with precision, and can easily be used for mechanically ventilated pediatric patients.

Show MeSH
Related in: MedlinePlus