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CT perfusion in acute stroke.

Khandelwal N - Indian J Radiol Imaging (2008)

Bottom Line: Stroke is a heterogeneous syndrome caused by multiple mechanisms, all of which result in disruption of normal cerebral blood flow and thereby cause cerebral dysfunction.Delay in diagnosis and treatment translates into increase neuronal loss and thereby increased morbidity.This article is an endeavor to explain the pathophysiology of cerebral ischemia and the role of CT perfusion in detecting it.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiodiagnosis and Imaging, PGIMER, Sector 12, Chandigarh, India.

ABSTRACT
Stroke is a heterogeneous syndrome caused by multiple mechanisms, all of which result in disruption of normal cerebral blood flow and thereby cause cerebral dysfunction. Its early diagnosis is important as its treatment is dependent on the time elapsed since ictus. Delay in diagnosis and treatment translates into increase neuronal loss and thereby increased morbidity. CT scan, and in particular perfusion CT, has helped greatly in the early diagnosis of stroke. This article is an endeavor to explain the pathophysiology of cerebral ischemia and the role of CT perfusion in detecting it.

No MeSH data available.


Related in: MedlinePlus

Time–attenuation curve of CBF showing normal flow (upper curve) and significant reduced flow in the infracted region (lower curve)
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Figure 0005: Time–attenuation curve of CBF showing normal flow (upper curve) and significant reduced flow in the infracted region (lower curve)

Mentions: Postprocessing of the data is done by using specialized software. It involves confirmation of certain parameters which are automatically chosen by the software, and it generates color perfusion maps as well as time–attenuation curves (TAC) from which TTP/MTT, CBV, and CBF can be calculated for any area of interest [Figure 5].


CT perfusion in acute stroke.

Khandelwal N - Indian J Radiol Imaging (2008)

Time–attenuation curve of CBF showing normal flow (upper curve) and significant reduced flow in the infracted region (lower curve)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2747454&req=5

Figure 0005: Time–attenuation curve of CBF showing normal flow (upper curve) and significant reduced flow in the infracted region (lower curve)
Mentions: Postprocessing of the data is done by using specialized software. It involves confirmation of certain parameters which are automatically chosen by the software, and it generates color perfusion maps as well as time–attenuation curves (TAC) from which TTP/MTT, CBV, and CBF can be calculated for any area of interest [Figure 5].

Bottom Line: Stroke is a heterogeneous syndrome caused by multiple mechanisms, all of which result in disruption of normal cerebral blood flow and thereby cause cerebral dysfunction.Delay in diagnosis and treatment translates into increase neuronal loss and thereby increased morbidity.This article is an endeavor to explain the pathophysiology of cerebral ischemia and the role of CT perfusion in detecting it.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiodiagnosis and Imaging, PGIMER, Sector 12, Chandigarh, India.

ABSTRACT
Stroke is a heterogeneous syndrome caused by multiple mechanisms, all of which result in disruption of normal cerebral blood flow and thereby cause cerebral dysfunction. Its early diagnosis is important as its treatment is dependent on the time elapsed since ictus. Delay in diagnosis and treatment translates into increase neuronal loss and thereby increased morbidity. CT scan, and in particular perfusion CT, has helped greatly in the early diagnosis of stroke. This article is an endeavor to explain the pathophysiology of cerebral ischemia and the role of CT perfusion in detecting it.

No MeSH data available.


Related in: MedlinePlus