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Case report: Fat-containing liver metastases from retroperitoneal liposarcoma.

Prakash M, Vyas S, Shanbhogue AK, Kang M, Dey P, Khandelwal N - Indian J Radiol Imaging (2008)

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A 54-year-old man, treated in the past for retroperitoneal liposarcoma, came for a follow-up CT scan... A contrast-enhanced CT scan of the abdomen showed a large 14 × 12 cm mass in the retroperitoneum with heterogeneous attenuation [Figure 2]... This was suggestive of a recurrent liposarcoma... There were multiple focal hypodense lesions showing fat attenuation (−30 to −70 HU) in both lobes of the liver, without enhancement [Figure 3]... CT scan can suggest a diagnosis of liposarcoma when fat is detected within a retroperitoneal mass... Huang et al. found only one patient with liver metastases among 354 patients with retroperitoneal dedifferentiated liposarcoma... A wide variety of hepatic mass lesions show fat attenuation on CT... These include benign conditions such as focal or geographic fatty change, pericaval fat, postoperative packing material (omentum), adenoma, focal nodular hyperplasia, lipoma, angiomyolipoma, and cystic teratoma as well as malignant liver lesions like hepatocellular carcinoma, primary and metastatic liposarcoma, and other metastases... Identification of fat within a liver lesion may be crucial for characterizing some of these lesions... The pattern of fatty change (macroscopic vs intracellular lipid) and whether the lesion contains only fat (e.g., lipoma, postoperative packing material, focal steatosis) or fat and soft tissue (e.g., adenoma, angiomyolipoma, teratoma, primary and metastatic liposarcoma and hepatocellular carcinoma) are factors that are useful in narrowing down the differential diagnosis... Although USG and CT scan can detect fat in the majority of the cases, MRI with chemical-shift imaging may be a better modality to detect fat, especially intracellular lipid... Basaran et al., in their review on fat-containing lesions of the liver, have described 16 different types of hepatic lesions that demonstrate fat within... In this case, local recurrence was found in both lobes of the liver, with multiple hypodense, fat-attenuation focal lesions on CT scan... This is an unusual finding, and the presence of fat was of help in pinpointing the nature of the metastases.

No MeSH data available.


Axial contrast-enhanced CT scans show multiple, hypodense, focal lesions in both lobes of the liver with fatty attenuation (arrows)
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Figure 0003: Axial contrast-enhanced CT scans show multiple, hypodense, focal lesions in both lobes of the liver with fatty attenuation (arrows)

Mentions: A contrast-enhanced CT scan of the abdomen showed a large 14 × 12 cm mass in the retroperitoneum with heterogeneous attenuation [Figure 2]. This was suggestive of a recurrent liposarcoma. There were multiple focal hypodense lesions showing fat attenuation (−30 to −70 HU) in both lobes of the liver, without enhancement [Figure 3]. USG-guided fine needle aspiration cytology (FNAC) showed features consistent with metastatic sarcoma.


Case report: Fat-containing liver metastases from retroperitoneal liposarcoma.

Prakash M, Vyas S, Shanbhogue AK, Kang M, Dey P, Khandelwal N - Indian J Radiol Imaging (2008)

Axial contrast-enhanced CT scans show multiple, hypodense, focal lesions in both lobes of the liver with fatty attenuation (arrows)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2747442&req=5

Figure 0003: Axial contrast-enhanced CT scans show multiple, hypodense, focal lesions in both lobes of the liver with fatty attenuation (arrows)
Mentions: A contrast-enhanced CT scan of the abdomen showed a large 14 × 12 cm mass in the retroperitoneum with heterogeneous attenuation [Figure 2]. This was suggestive of a recurrent liposarcoma. There were multiple focal hypodense lesions showing fat attenuation (−30 to −70 HU) in both lobes of the liver, without enhancement [Figure 3]. USG-guided fine needle aspiration cytology (FNAC) showed features consistent with metastatic sarcoma.

View Article: PubMed Central - PubMed

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

A 54-year-old man, treated in the past for retroperitoneal liposarcoma, came for a follow-up CT scan... A contrast-enhanced CT scan of the abdomen showed a large 14 × 12 cm mass in the retroperitoneum with heterogeneous attenuation [Figure 2]... This was suggestive of a recurrent liposarcoma... There were multiple focal hypodense lesions showing fat attenuation (−30 to −70 HU) in both lobes of the liver, without enhancement [Figure 3]... CT scan can suggest a diagnosis of liposarcoma when fat is detected within a retroperitoneal mass... Huang et al. found only one patient with liver metastases among 354 patients with retroperitoneal dedifferentiated liposarcoma... A wide variety of hepatic mass lesions show fat attenuation on CT... These include benign conditions such as focal or geographic fatty change, pericaval fat, postoperative packing material (omentum), adenoma, focal nodular hyperplasia, lipoma, angiomyolipoma, and cystic teratoma as well as malignant liver lesions like hepatocellular carcinoma, primary and metastatic liposarcoma, and other metastases... Identification of fat within a liver lesion may be crucial for characterizing some of these lesions... The pattern of fatty change (macroscopic vs intracellular lipid) and whether the lesion contains only fat (e.g., lipoma, postoperative packing material, focal steatosis) or fat and soft tissue (e.g., adenoma, angiomyolipoma, teratoma, primary and metastatic liposarcoma and hepatocellular carcinoma) are factors that are useful in narrowing down the differential diagnosis... Although USG and CT scan can detect fat in the majority of the cases, MRI with chemical-shift imaging may be a better modality to detect fat, especially intracellular lipid... Basaran et al., in their review on fat-containing lesions of the liver, have described 16 different types of hepatic lesions that demonstrate fat within... In this case, local recurrence was found in both lobes of the liver, with multiple hypodense, fat-attenuation focal lesions on CT scan... This is an unusual finding, and the presence of fat was of help in pinpointing the nature of the metastases.

No MeSH data available.