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Recurrent lymphocytic meningitis positive for herpes simplex virus type 2.

Kallio-Laine K, Seppänen M, Kautiainen H, Lokki ML, Lappalainen M, Valtonen V, Färkkilä M, Kalso E - Emerging Infect. Dis. (2009)

Bottom Line: We found the prevalence of recurrent lymphocytic meningitis associated with herpes simplex virus type 2 (HSV-2) was 2.2/100,000 population in Finland during 1996-2006, higher than previous estimates.PCR was most sensitive in detecting HSV-2 DNA from cerebrospinal fluid if the sample was taken 2-5 days after symptom onset.

View Article: PubMed Central - PubMed

Affiliation: Helsinki University Central Hospital, Helsinki, Finland. katariina.kallio-laine@helsinki.fi

ABSTRACT
We found the prevalence of recurrent lymphocytic meningitis associated with herpes simplex virus type 2 (HSV-2) was 2.2/100,000 population in Finland during 1996-2006, higher than previous estimates. PCR was most sensitive in detecting HSV-2 DNA from cerebrospinal fluid if the sample was taken 2-5 days after symptom onset.

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Related in: MedlinePlus

Kaplan-Meier curve showing cumulative proportions of the second recurrent lymphocytic meningitis episode (the time from the first episode to the first recurrence, years) in patients, Finland. 95% confidence intervals were obtained by bias-corrected bootstrapping.
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Figure 1: Kaplan-Meier curve showing cumulative proportions of the second recurrent lymphocytic meningitis episode (the time from the first episode to the first recurrence, years) in patients, Finland. 95% confidence intervals were obtained by bias-corrected bootstrapping.

Mentions: The median patient follow-up time was 16.2 years (range 4–32 years). The number of meningitis episodes per case-patient varied from 2 to 13 (Table 1), and the number of meningitis episodes per follow-up year was 0.28 (95% CI 0.22–0.35). The time between the first and the second episode of meningitis ranged from 1 to 216 months (median 47 months; Figure).


Recurrent lymphocytic meningitis positive for herpes simplex virus type 2.

Kallio-Laine K, Seppänen M, Kautiainen H, Lokki ML, Lappalainen M, Valtonen V, Färkkilä M, Kalso E - Emerging Infect. Dis. (2009)

Kaplan-Meier curve showing cumulative proportions of the second recurrent lymphocytic meningitis episode (the time from the first episode to the first recurrence, years) in patients, Finland. 95% confidence intervals were obtained by bias-corrected bootstrapping.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2744243&req=5

Figure 1: Kaplan-Meier curve showing cumulative proportions of the second recurrent lymphocytic meningitis episode (the time from the first episode to the first recurrence, years) in patients, Finland. 95% confidence intervals were obtained by bias-corrected bootstrapping.
Mentions: The median patient follow-up time was 16.2 years (range 4–32 years). The number of meningitis episodes per case-patient varied from 2 to 13 (Table 1), and the number of meningitis episodes per follow-up year was 0.28 (95% CI 0.22–0.35). The time between the first and the second episode of meningitis ranged from 1 to 216 months (median 47 months; Figure).

Bottom Line: We found the prevalence of recurrent lymphocytic meningitis associated with herpes simplex virus type 2 (HSV-2) was 2.2/100,000 population in Finland during 1996-2006, higher than previous estimates.PCR was most sensitive in detecting HSV-2 DNA from cerebrospinal fluid if the sample was taken 2-5 days after symptom onset.

View Article: PubMed Central - PubMed

Affiliation: Helsinki University Central Hospital, Helsinki, Finland. katariina.kallio-laine@helsinki.fi

ABSTRACT
We found the prevalence of recurrent lymphocytic meningitis associated with herpes simplex virus type 2 (HSV-2) was 2.2/100,000 population in Finland during 1996-2006, higher than previous estimates. PCR was most sensitive in detecting HSV-2 DNA from cerebrospinal fluid if the sample was taken 2-5 days after symptom onset.

Show MeSH
Related in: MedlinePlus