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Unusual synchronous presentation of maxillary sinus fibrosarcoma and gemistocytic astrocytoma with a complication called leukocytoclastic vasculitis: a case report.

Cadir B, Karahan N, Nasir S, Aydin MA, Turkaslan SS - Eur J Dent (2009)

Bottom Line: We report synchronous presentation of maxillary sinus fibrosarcoma and gemistocytic astrocytoma which is, to our knowledge, unique in the literature.Both tumors metastases to other organ rarely and the metastatic spread of gemistocytic astrocytoma to fibrosarcoma or vice versa have also not been reported in the literature yet.This report discusses the clinical course of the disease, outcome of the treatment approach and survival as well as an unusual occurrence of leukocytoclastic vasculitis during the course of radiotherapy in such unusual presentation.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Suleyman Demirel University, Isparta, Turkey.

ABSTRACT
Fibrosarcoma of the paranasal sinuses is extremely rare pathology and there is limited report in the literature. We report synchronous presentation of maxillary sinus fibrosarcoma and gemistocytic astrocytoma which is, to our knowledge, unique in the literature. Both tumors metastases to other organ rarely and the metastatic spread of gemistocytic astrocytoma to fibrosarcoma or vice versa have also not been reported in the literature yet. This report discusses the clinical course of the disease, outcome of the treatment approach and survival as well as an unusual occurrence of leukocytoclastic vasculitis during the course of radiotherapy in such unusual presentation.

No MeSH data available.


Related in: MedlinePlus

The histopathological sections of fibrosarcoma. Spindle-cells under the pseudo-stratified ciliary’s epithelium at the surface, spindle-cells crossing each other (6a (40xHE)) and a mitosis (6b (400xHE)) are seen. Vimentin is diffuse positive in tumor tissue (6c (100xVimentin)), SMA is negative in tumor tissue and positive in the vessel wall (6d (100xSMA)).
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f6-0030233: The histopathological sections of fibrosarcoma. Spindle-cells under the pseudo-stratified ciliary’s epithelium at the surface, spindle-cells crossing each other (6a (40xHE)) and a mitosis (6b (400xHE)) are seen. Vimentin is diffuse positive in tumor tissue (6c (100xVimentin)), SMA is negative in tumor tissue and positive in the vessel wall (6d (100xSMA)).

Mentions: During an incision biopsy, destruction of the anterolateral wall of the left-maxillary sinus was observed. The tumor under the periost was in accord with the maxillary sinus mucosa, but continued with a soft, fragile, hyperplasic, reddish-purple lesion underneath. The lesion had tendency to bleeding easily and the hemorrhage occurred during biopsy was able to be controlled with haemostatic agents. Histopathological examination revealed it to be a well differentiated (Grade I) fibrosarcoma (Figure 6a, b, c, d). HE-stained histopathological sections of fibrosarcoma showed spindle-cells crossing each other under the pseudo-stratified ciliary’s epithelium at the surface (Figure 6a (40xHE)) and a mitosis (Figure 6b, arrow, (400xHE)). Vimentin was seen diffuse positive in tumor tissue (Figure 6c (100xVimentin)) whereas SMA was seen negative in tumor tissue and positive in the vessel wall (Figure 6d (100xSMA)).


Unusual synchronous presentation of maxillary sinus fibrosarcoma and gemistocytic astrocytoma with a complication called leukocytoclastic vasculitis: a case report.

Cadir B, Karahan N, Nasir S, Aydin MA, Turkaslan SS - Eur J Dent (2009)

The histopathological sections of fibrosarcoma. Spindle-cells under the pseudo-stratified ciliary’s epithelium at the surface, spindle-cells crossing each other (6a (40xHE)) and a mitosis (6b (400xHE)) are seen. Vimentin is diffuse positive in tumor tissue (6c (100xVimentin)), SMA is negative in tumor tissue and positive in the vessel wall (6d (100xSMA)).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2741197&req=5

f6-0030233: The histopathological sections of fibrosarcoma. Spindle-cells under the pseudo-stratified ciliary’s epithelium at the surface, spindle-cells crossing each other (6a (40xHE)) and a mitosis (6b (400xHE)) are seen. Vimentin is diffuse positive in tumor tissue (6c (100xVimentin)), SMA is negative in tumor tissue and positive in the vessel wall (6d (100xSMA)).
Mentions: During an incision biopsy, destruction of the anterolateral wall of the left-maxillary sinus was observed. The tumor under the periost was in accord with the maxillary sinus mucosa, but continued with a soft, fragile, hyperplasic, reddish-purple lesion underneath. The lesion had tendency to bleeding easily and the hemorrhage occurred during biopsy was able to be controlled with haemostatic agents. Histopathological examination revealed it to be a well differentiated (Grade I) fibrosarcoma (Figure 6a, b, c, d). HE-stained histopathological sections of fibrosarcoma showed spindle-cells crossing each other under the pseudo-stratified ciliary’s epithelium at the surface (Figure 6a (40xHE)) and a mitosis (Figure 6b, arrow, (400xHE)). Vimentin was seen diffuse positive in tumor tissue (Figure 6c (100xVimentin)) whereas SMA was seen negative in tumor tissue and positive in the vessel wall (Figure 6d (100xSMA)).

Bottom Line: We report synchronous presentation of maxillary sinus fibrosarcoma and gemistocytic astrocytoma which is, to our knowledge, unique in the literature.Both tumors metastases to other organ rarely and the metastatic spread of gemistocytic astrocytoma to fibrosarcoma or vice versa have also not been reported in the literature yet.This report discusses the clinical course of the disease, outcome of the treatment approach and survival as well as an unusual occurrence of leukocytoclastic vasculitis during the course of radiotherapy in such unusual presentation.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Suleyman Demirel University, Isparta, Turkey.

ABSTRACT
Fibrosarcoma of the paranasal sinuses is extremely rare pathology and there is limited report in the literature. We report synchronous presentation of maxillary sinus fibrosarcoma and gemistocytic astrocytoma which is, to our knowledge, unique in the literature. Both tumors metastases to other organ rarely and the metastatic spread of gemistocytic astrocytoma to fibrosarcoma or vice versa have also not been reported in the literature yet. This report discusses the clinical course of the disease, outcome of the treatment approach and survival as well as an unusual occurrence of leukocytoclastic vasculitis during the course of radiotherapy in such unusual presentation.

No MeSH data available.


Related in: MedlinePlus