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Genomics and Environmental Regulation: Science, Ethics and Law

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This timely work focuses on the potential and problems arising from the application of genomic technologies to toxicology and environmental policy, and is divided into four parts—“Environmental Policy Perspectives,” “Legal Perspectives,” “Occupational Health Perspectives,” and “Ethical and Philosophical Perspectives”—each containing several chapters by the editors and other leading scholars... What makes these topics of such interest and complexity is that scientists can perceive the potential value of genomic technologies that have not yet been developed sufficiently to be applied... Ethicists and the legal system perceive both the potential value and the challenges associated with the applications of genomic technology... In the first chapter, Gary Marchant focuses on toxicogenomics and explores the many applications, challenges, and limitations in using data from a discipline that is in a dynamic state of development... Richard Phillips describes studies on predictive toxicology and understanding mechanisms and modes of action in risk assessment; he provides insights into the actual state of development of toxicogenomics as well as issues related to genetic susceptibility... In “Legal Perspectives,” Lynn Burgeson discusses challenges in applying toxicogenomic data in federal regulatory decisions... She discusses genomic data, information quality, and peer review in the context of agency actions in adverse effects reporting... And Marchant discusses the setting of national ambient air quality standards (NAAQS), perhaps one of the first applications of genetic susceptibility data... He believes that the NAAQS are among the nation’s most important environmental regulations because they provide the greatest health benefits and largest compliance costs... The chapter comprehensively discusses the NAAQS program, genetic susceptibility to criteria air pollutants, normative issues, and alternative approaches... Rothstein deals with occupational and health issues raised by the use of toxicogenomics in the workplace, including the Occupational Safety and Health Act, Americans with Disabilities Act, genetic testing and monitoring, and nondiscrimination laws... Kenneth Mossman discusses genetic susceptibility and radiological health and safety... The preface nicely presents a statement of the goals of the book and a concise synopsis of each chapter... The book will be of particular value to those whose interests bridge the technical and legal–ethical issues at the forefront of toxicology today.

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Genomics and Environmental Regulation: Science, Ethics and Law
© Copyright Policy - public-domain
Related In: Results  -  Collection

License
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getmorefigures.php?uid=PMC2737047&req=5

View Article: PubMed Central

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

This timely work focuses on the potential and problems arising from the application of genomic technologies to toxicology and environmental policy, and is divided into four parts—“Environmental Policy Perspectives,” “Legal Perspectives,” “Occupational Health Perspectives,” and “Ethical and Philosophical Perspectives”—each containing several chapters by the editors and other leading scholars... What makes these topics of such interest and complexity is that scientists can perceive the potential value of genomic technologies that have not yet been developed sufficiently to be applied... Ethicists and the legal system perceive both the potential value and the challenges associated with the applications of genomic technology... In the first chapter, Gary Marchant focuses on toxicogenomics and explores the many applications, challenges, and limitations in using data from a discipline that is in a dynamic state of development... Richard Phillips describes studies on predictive toxicology and understanding mechanisms and modes of action in risk assessment; he provides insights into the actual state of development of toxicogenomics as well as issues related to genetic susceptibility... In “Legal Perspectives,” Lynn Burgeson discusses challenges in applying toxicogenomic data in federal regulatory decisions... She discusses genomic data, information quality, and peer review in the context of agency actions in adverse effects reporting... And Marchant discusses the setting of national ambient air quality standards (NAAQS), perhaps one of the first applications of genetic susceptibility data... He believes that the NAAQS are among the nation’s most important environmental regulations because they provide the greatest health benefits and largest compliance costs... The chapter comprehensively discusses the NAAQS program, genetic susceptibility to criteria air pollutants, normative issues, and alternative approaches... Rothstein deals with occupational and health issues raised by the use of toxicogenomics in the workplace, including the Occupational Safety and Health Act, Americans with Disabilities Act, genetic testing and monitoring, and nondiscrimination laws... Kenneth Mossman discusses genetic susceptibility and radiological health and safety... The preface nicely presents a statement of the goals of the book and a concise synopsis of each chapter... The book will be of particular value to those whose interests bridge the technical and legal–ethical issues at the forefront of toxicology today.

No MeSH data available.