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Antioxidant and radical scavenging activity of human colostrum, transitional and mature milk.

Zarban A, Taheri F, Chahkandi T, Sharifzadeh G, Khorashadizadeh M - J Clin Biochem Nutr (2009)

Bottom Line: There was a high significant correlation between the results of these two methods.The relationship between the antioxidant content of human milk and maternal plasma was also significant.These data suggest that using colostrum, with high antioxidant potential during the first days of life is vital; moreover, reduction in total TAC during the course of lactation may needs more attention about nutritional status.

View Article: PubMed Central - PubMed

Affiliation: Biochemistry department, Faculty of Medicine, Birjand University of Medical Sciences, Birjand 9717853577, Iran.

ABSTRACT
Human milk from healthy women contains numerous nutrients such as antioxidants which are necessary for newborns. The aim of this study was to evaluate the changes of total antioxidant capacity (TAC) and free radical scavenging activity in human milk during the first six month period of lactation and also its relationship to maternal plasma. A total of 505 milk samples (colostrum, transitional and mature milks) collected from 115 healthy women with full term newborns. Blood plasma was obtained from 58 women at 3 months postpartum. The TAC of samples were measured by Ferric Reducing/Antioxidant Power assay and free radical scavenging activity were evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. TAC was obviously higher in colostrums than transitional and mature milks. Similar results were observed for DPPH radical scavenging activity of the samples. There was a high significant correlation between the results of these two methods. The relationship between the antioxidant content of human milk and maternal plasma was also significant. These data suggest that using colostrum, with high antioxidant potential during the first days of life is vital; moreover, reduction in total TAC during the course of lactation may needs more attention about nutritional status.

No MeSH data available.


The correlation between TAC of breast milk and maternal plasma (r = 0.267, p<0.05).
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Figure 2: The correlation between TAC of breast milk and maternal plasma (r = 0.267, p<0.05).

Mentions: The mean of maternal plasma antioxidant capacity was 842.0 ± 123.5 µmol/L ranged from 565.2 to 1193.4 µmol/L. This level was closely near to the mean of breast milk antioxidant capacity at 90 ± 7 days that was 862.7 ±  457.7 µmol/L and ranged from 121.5 to 3816 µmol/L and there was a significant correlation between the maternal plasma and breast milk antioxidant capacity (r = 0.267, p<0.05) (Fig. 2).


Antioxidant and radical scavenging activity of human colostrum, transitional and mature milk.

Zarban A, Taheri F, Chahkandi T, Sharifzadeh G, Khorashadizadeh M - J Clin Biochem Nutr (2009)

The correlation between TAC of breast milk and maternal plasma (r = 0.267, p<0.05).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2735626&req=5

Figure 2: The correlation between TAC of breast milk and maternal plasma (r = 0.267, p<0.05).
Mentions: The mean of maternal plasma antioxidant capacity was 842.0 ± 123.5 µmol/L ranged from 565.2 to 1193.4 µmol/L. This level was closely near to the mean of breast milk antioxidant capacity at 90 ± 7 days that was 862.7 ±  457.7 µmol/L and ranged from 121.5 to 3816 µmol/L and there was a significant correlation between the maternal plasma and breast milk antioxidant capacity (r = 0.267, p<0.05) (Fig. 2).

Bottom Line: There was a high significant correlation between the results of these two methods.The relationship between the antioxidant content of human milk and maternal plasma was also significant.These data suggest that using colostrum, with high antioxidant potential during the first days of life is vital; moreover, reduction in total TAC during the course of lactation may needs more attention about nutritional status.

View Article: PubMed Central - PubMed

Affiliation: Biochemistry department, Faculty of Medicine, Birjand University of Medical Sciences, Birjand 9717853577, Iran.

ABSTRACT
Human milk from healthy women contains numerous nutrients such as antioxidants which are necessary for newborns. The aim of this study was to evaluate the changes of total antioxidant capacity (TAC) and free radical scavenging activity in human milk during the first six month period of lactation and also its relationship to maternal plasma. A total of 505 milk samples (colostrum, transitional and mature milks) collected from 115 healthy women with full term newborns. Blood plasma was obtained from 58 women at 3 months postpartum. The TAC of samples were measured by Ferric Reducing/Antioxidant Power assay and free radical scavenging activity were evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. TAC was obviously higher in colostrums than transitional and mature milks. Similar results were observed for DPPH radical scavenging activity of the samples. There was a high significant correlation between the results of these two methods. The relationship between the antioxidant content of human milk and maternal plasma was also significant. These data suggest that using colostrum, with high antioxidant potential during the first days of life is vital; moreover, reduction in total TAC during the course of lactation may needs more attention about nutritional status.

No MeSH data available.