Limits...
Adhesion molecule-modified biomaterials for neural tissue engineering.

Rao SS, Winter JO - Front Neuroeng (2009)

Bottom Line: These tethered molecules provide cues to regenerating neurons that recapitulate the native brain environment.Improving cell adhesive potential of non-adhesive biomaterials is therefore a common goal in neural tissue engineering.Additionally, patterning of AMs for achieving specific neuronal responses is explored.

View Article: PubMed Central - PubMed

Affiliation: William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University Columbus, OH, USA.

ABSTRACT
Adhesion molecules (AMs) represent one class of biomolecules that promote central nervous system regeneration. These tethered molecules provide cues to regenerating neurons that recapitulate the native brain environment. Improving cell adhesive potential of non-adhesive biomaterials is therefore a common goal in neural tissue engineering. This review discusses common AMs used in neural biomaterials and the mechanism of cell attachment to these AMs. Methods to modify materials with AMs are discussed and compared. Additionally, patterning of AMs for achieving specific neuronal responses is explored.

No MeSH data available.


Related in: MedlinePlus

Biomaterial modification techniques.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC2723915&req=5

Figure 9: Biomaterial modification techniques.

Mentions: Each biomaterial modification technique discussed is outlined in Figure 9.


Adhesion molecule-modified biomaterials for neural tissue engineering.

Rao SS, Winter JO - Front Neuroeng (2009)

Biomaterial modification techniques.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2723915&req=5

Figure 9: Biomaterial modification techniques.
Mentions: Each biomaterial modification technique discussed is outlined in Figure 9.

Bottom Line: These tethered molecules provide cues to regenerating neurons that recapitulate the native brain environment.Improving cell adhesive potential of non-adhesive biomaterials is therefore a common goal in neural tissue engineering.Additionally, patterning of AMs for achieving specific neuronal responses is explored.

View Article: PubMed Central - PubMed

Affiliation: William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University Columbus, OH, USA.

ABSTRACT
Adhesion molecules (AMs) represent one class of biomolecules that promote central nervous system regeneration. These tethered molecules provide cues to regenerating neurons that recapitulate the native brain environment. Improving cell adhesive potential of non-adhesive biomaterials is therefore a common goal in neural tissue engineering. This review discusses common AMs used in neural biomaterials and the mechanism of cell attachment to these AMs. Methods to modify materials with AMs are discussed and compared. Additionally, patterning of AMs for achieving specific neuronal responses is explored.

No MeSH data available.


Related in: MedlinePlus