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Analysis of endoscopic electronic image of intramucosal gastric carcinoma using a software program for calculating hemoglobin index.

Kim GH, Kim KB, Lim EK, Choi SH, Kim TO, Heo J, Kang DH, Song GA, Cho M, Park do Y - J. Korean Med. Sci. (2006)

Bottom Line: The C/N ratio in the intestinal-type carcinoma group was higher than that in the diffuse-type carcinoma group (p<0.001).In the diffuse-type carcinoma group, the C/N ratio in the body was lower than that in the antrum (p=0.022).The accuracy rate, sensitivity, specificity, and the positive and negative predictive values for the differential diagnosis of the diffuse-type carcinoma from the intestinal-type carcinoma were 94.5%, 94.1%, 94.7%, 88.9% and 97.3%, respectively.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Pusan National University College of Medicine, 1-10 Ami-Dong, Seo-Gu, Busan, Korea.

ABSTRACT
Hemoglobin is the predominent pigment in the gastrointestinal mucosa, and the development of electronic endoscopy has made it possible to quantitatively measure the mucosal hemoglobin volume, by using a hemoglobin index (IHb). The aims of this study were to make a software program to calculate the IHb and then to investigate whether the mucosal IHb determined from the electronic endoscopic data is a useful marker for evaluating the color of intramucosal gastric carcinoma with regard to its value for discriminating between the histologic types. We made a software program for calculating the IHb in the endoscopic images. By using this program, the mean values of the IHb for the carcinoma (IHb-C) and those of the IHb for the surrounding non-cancerous mucosa (IHb-N) were calculated in 75 intestinal-type and 34 diffuse-type intramucosal gastric carcinomas. We then analyzed the ratio of the IHb-C to the IHb-N (C/N ratio). The C/N ratio in the intestinal-type carcinoma group was higher than that in the diffuse-type carcinoma group (p<0.001). In the diffuse-type carcinoma group, the C/N ratio in the body was lower than that in the antrum (p=0.022). The accuracy rate, sensitivity, specificity, and the positive and negative predictive values for the differential diagnosis of the diffuse-type carcinoma from the intestinal-type carcinoma were 94.5%, 94.1%, 94.7%, 88.9% and 97.3%, respectively. IHb is useful for making quantitative measurement of the endoscopic color in the intramucosal gastric carcinoma, and the C/N ratio by using the IHb would be helpful for distinguishing the diffuse-type carcinoma from the intestinal-type carcinoma.

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The C/N ratio in the diffuse-type carcinoma group and in the intestinal-type carcinoma group.
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Figure 6: The C/N ratio in the diffuse-type carcinoma group and in the intestinal-type carcinoma group.

Mentions: The mean C/N ratio in the intestinal-type carcinoma group was higher than that in the diffuse-type carcinoma group: 1.28±0.19 vs. 0.81±0.18, respectively (p<0.001, Fig. 6). According to the location of the carcinoma, there was no difference in the C/N ratio between the antrum and the body in the intestinal-type carcinoma group (1.27±0.16 vs. 1.32±0.25, respectively, p=0.421). But in the diffuse-type carcinoma group, the C/N ratio in the body was lower than that in the antrum (0.72±0.18 vs. 0.86±0.16, respectively, p=0.022, Fig. 7).


Analysis of endoscopic electronic image of intramucosal gastric carcinoma using a software program for calculating hemoglobin index.

Kim GH, Kim KB, Lim EK, Choi SH, Kim TO, Heo J, Kang DH, Song GA, Cho M, Park do Y - J. Korean Med. Sci. (2006)

The C/N ratio in the diffuse-type carcinoma group and in the intestinal-type carcinoma group.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2721926&req=5

Figure 6: The C/N ratio in the diffuse-type carcinoma group and in the intestinal-type carcinoma group.
Mentions: The mean C/N ratio in the intestinal-type carcinoma group was higher than that in the diffuse-type carcinoma group: 1.28±0.19 vs. 0.81±0.18, respectively (p<0.001, Fig. 6). According to the location of the carcinoma, there was no difference in the C/N ratio between the antrum and the body in the intestinal-type carcinoma group (1.27±0.16 vs. 1.32±0.25, respectively, p=0.421). But in the diffuse-type carcinoma group, the C/N ratio in the body was lower than that in the antrum (0.72±0.18 vs. 0.86±0.16, respectively, p=0.022, Fig. 7).

Bottom Line: The C/N ratio in the intestinal-type carcinoma group was higher than that in the diffuse-type carcinoma group (p<0.001).In the diffuse-type carcinoma group, the C/N ratio in the body was lower than that in the antrum (p=0.022).The accuracy rate, sensitivity, specificity, and the positive and negative predictive values for the differential diagnosis of the diffuse-type carcinoma from the intestinal-type carcinoma were 94.5%, 94.1%, 94.7%, 88.9% and 97.3%, respectively.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Pusan National University College of Medicine, 1-10 Ami-Dong, Seo-Gu, Busan, Korea.

ABSTRACT
Hemoglobin is the predominent pigment in the gastrointestinal mucosa, and the development of electronic endoscopy has made it possible to quantitatively measure the mucosal hemoglobin volume, by using a hemoglobin index (IHb). The aims of this study were to make a software program to calculate the IHb and then to investigate whether the mucosal IHb determined from the electronic endoscopic data is a useful marker for evaluating the color of intramucosal gastric carcinoma with regard to its value for discriminating between the histologic types. We made a software program for calculating the IHb in the endoscopic images. By using this program, the mean values of the IHb for the carcinoma (IHb-C) and those of the IHb for the surrounding non-cancerous mucosa (IHb-N) were calculated in 75 intestinal-type and 34 diffuse-type intramucosal gastric carcinomas. We then analyzed the ratio of the IHb-C to the IHb-N (C/N ratio). The C/N ratio in the intestinal-type carcinoma group was higher than that in the diffuse-type carcinoma group (p<0.001). In the diffuse-type carcinoma group, the C/N ratio in the body was lower than that in the antrum (p=0.022). The accuracy rate, sensitivity, specificity, and the positive and negative predictive values for the differential diagnosis of the diffuse-type carcinoma from the intestinal-type carcinoma were 94.5%, 94.1%, 94.7%, 88.9% and 97.3%, respectively. IHb is useful for making quantitative measurement of the endoscopic color in the intramucosal gastric carcinoma, and the C/N ratio by using the IHb would be helpful for distinguishing the diffuse-type carcinoma from the intestinal-type carcinoma.

Show MeSH
Related in: MedlinePlus