Limits...
Lipid profile in oral submucous fibrosis.

Mehrotra R, Pandya S, Chaudhary AK, Singh HP, Jaiswal RK, Singh M, Gupta SC, Singh M - Lipids Health Dis (2009)

Bottom Line: A significant decrease in plasma total cholesterol, HDLC and Apo-A1 was observed in patients with OSMF as compared to the controls.Thus an inverse relationship between plasma lipid levels and patients was found in OSMF.The lower levels of plasma cholesterol and other lipid constituents in patients might be due to their increased utilization.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Pathology, M.L.N. Medical College, Allahabad, India. rm8509@gmail.com

ABSTRACT

Background: Changes in lipid profile have long been associated with malignancies as lipids play a key role in maintenance of cell integrity. This study evaluated the alterations in extended lipid profile in untreated patients of oral submucous fibrosis (OSMF) and studied the correlation between lipid levels with tobacco consumption.

Materials and methods: In this hospital-based study, 65 clinically diagnosed and histopathologically proven patients of OSMF and 42 age and sex matched controls were studied. In these samples serum lipids including: (i) Total cholesterol, (ii) LDL cholesterol (LDLC), (iii) HDL cholesterol (HDLC) (iv) VLDL cholesterol (VLDLC) (v) triglycerides (vi) Apo-A1 (viii) Apo-B and (viii) LPa were analyzed.

Results: A significant decrease in plasma total cholesterol, HDLC and Apo-A1 was observed in patients with OSMF as compared to the controls. Thus an inverse relationship between plasma lipid levels and patients was found in OSMF.

Conclusion: The lower levels of plasma cholesterol and other lipid constituents in patients might be due to their increased utilization. The findings strongly warrant an in-depth study of alterations in plasma lipid profile in patients with oral precancerous conditions.

Show MeSH

Related in: MedlinePlus

Showing Value of Apo-B in patients of OSMF.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC2721834&req=5

Figure 8: Showing Value of Apo-B in patients of OSMF.

Mentions: There was a significant increase in serum total cholesterol, LDL, VLDL and triglycerides levels (Figure 2, 3, 4). On the other hand, there was significant decrease in HDL and Apo-A1 (Figure 5, 6). No change was observed in Apo-B or Lipoprotein-A (Figure 7, 8) in the patient category compared to the controls (Table 3).


Lipid profile in oral submucous fibrosis.

Mehrotra R, Pandya S, Chaudhary AK, Singh HP, Jaiswal RK, Singh M, Gupta SC, Singh M - Lipids Health Dis (2009)

Showing Value of Apo-B in patients of OSMF.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2721834&req=5

Figure 8: Showing Value of Apo-B in patients of OSMF.
Mentions: There was a significant increase in serum total cholesterol, LDL, VLDL and triglycerides levels (Figure 2, 3, 4). On the other hand, there was significant decrease in HDL and Apo-A1 (Figure 5, 6). No change was observed in Apo-B or Lipoprotein-A (Figure 7, 8) in the patient category compared to the controls (Table 3).

Bottom Line: A significant decrease in plasma total cholesterol, HDLC and Apo-A1 was observed in patients with OSMF as compared to the controls.Thus an inverse relationship between plasma lipid levels and patients was found in OSMF.The lower levels of plasma cholesterol and other lipid constituents in patients might be due to their increased utilization.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Pathology, M.L.N. Medical College, Allahabad, India. rm8509@gmail.com

ABSTRACT

Background: Changes in lipid profile have long been associated with malignancies as lipids play a key role in maintenance of cell integrity. This study evaluated the alterations in extended lipid profile in untreated patients of oral submucous fibrosis (OSMF) and studied the correlation between lipid levels with tobacco consumption.

Materials and methods: In this hospital-based study, 65 clinically diagnosed and histopathologically proven patients of OSMF and 42 age and sex matched controls were studied. In these samples serum lipids including: (i) Total cholesterol, (ii) LDL cholesterol (LDLC), (iii) HDL cholesterol (HDLC) (iv) VLDL cholesterol (VLDLC) (v) triglycerides (vi) Apo-A1 (viii) Apo-B and (viii) LPa were analyzed.

Results: A significant decrease in plasma total cholesterol, HDLC and Apo-A1 was observed in patients with OSMF as compared to the controls. Thus an inverse relationship between plasma lipid levels and patients was found in OSMF.

Conclusion: The lower levels of plasma cholesterol and other lipid constituents in patients might be due to their increased utilization. The findings strongly warrant an in-depth study of alterations in plasma lipid profile in patients with oral precancerous conditions.

Show MeSH
Related in: MedlinePlus