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Schwannoma of the eyelid: apropos of two cases.

Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A - Indian J Ophthalmol (2009 Jul-Aug)

Bottom Line: Schwannoma of ophthalmic interest is rare although it has been reported in relation with the orbit, and less frequently with the uveal tract and conjunctiva.Up until now, only eight cases have been reported in literature.Herein, we report two cases of eyelid schwannoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Charles Nicolle University Hospital, Tunis, Tunisia. fr.touzri@gnet.tn

ABSTRACT
Schwannoma, also referred to as neurilemmoma, is a benign tumor of peripheral nerve arising from Schwann cells that form the neural sheath. Schwannoma of ophthalmic interest is rare although it has been reported in relation with the orbit, and less frequently with the uveal tract and conjunctiva. Isolated eyelid schwannoma is extremely uncommon. Up until now, only eight cases have been reported in literature. Herein, we report two cases of eyelid schwannoma.

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Histopathology of Case 2: Antoni A pattern with fascicules and bundles of non-pigmented spindle cells with elongated bland nuclei (H and E, ×25)
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Figure 0003: Histopathology of Case 2: Antoni A pattern with fascicules and bundles of non-pigmented spindle cells with elongated bland nuclei (H and E, ×25)

Mentions: Schwannoma (or neurilemmoma) is made up of proliferating Schwann cells of peripheral nerve sheaths. It is a neoplasm which occurs wherever schwann cells are present, that is in any myelinated peripheral nerve. In most cases, while schwannoma is sporadically manifested as a single benign neoplasm, the presence of multiple schwannomas in one patient is usually indicative of neurofibromatosis 2 (NF-2) [Fig. 3]. However, the term schwannomatosis or neurilemmomatosis has been used to describe patients with multiple non-vestibular schwannomas with no other stigmatas of NF-2 or NF-1.[10]


Schwannoma of the eyelid: apropos of two cases.

Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A - Indian J Ophthalmol (2009 Jul-Aug)

Histopathology of Case 2: Antoni A pattern with fascicules and bundles of non-pigmented spindle cells with elongated bland nuclei (H and E, ×25)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2712707&req=5

Figure 0003: Histopathology of Case 2: Antoni A pattern with fascicules and bundles of non-pigmented spindle cells with elongated bland nuclei (H and E, ×25)
Mentions: Schwannoma (or neurilemmoma) is made up of proliferating Schwann cells of peripheral nerve sheaths. It is a neoplasm which occurs wherever schwann cells are present, that is in any myelinated peripheral nerve. In most cases, while schwannoma is sporadically manifested as a single benign neoplasm, the presence of multiple schwannomas in one patient is usually indicative of neurofibromatosis 2 (NF-2) [Fig. 3]. However, the term schwannomatosis or neurilemmomatosis has been used to describe patients with multiple non-vestibular schwannomas with no other stigmatas of NF-2 or NF-1.[10]

Bottom Line: Schwannoma of ophthalmic interest is rare although it has been reported in relation with the orbit, and less frequently with the uveal tract and conjunctiva.Up until now, only eight cases have been reported in literature.Herein, we report two cases of eyelid schwannoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Charles Nicolle University Hospital, Tunis, Tunisia. fr.touzri@gnet.tn

ABSTRACT
Schwannoma, also referred to as neurilemmoma, is a benign tumor of peripheral nerve arising from Schwann cells that form the neural sheath. Schwannoma of ophthalmic interest is rare although it has been reported in relation with the orbit, and less frequently with the uveal tract and conjunctiva. Isolated eyelid schwannoma is extremely uncommon. Up until now, only eight cases have been reported in literature. Herein, we report two cases of eyelid schwannoma.

Show MeSH
Related in: MedlinePlus