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Aniridia associated with congenital aphakia and secondary glaucoma.

Moreker M, Parikh R, Parikh SR, Thomas R - Indian J Ophthalmol (2009 Jul-Aug)

Bottom Line: After an unsuccessful medical management, he underwent trabeculectomy with mitomycin C and anterior vitrectomy under local anesthesia in his left eye.Postoperatively, at the end of six months, intraocular pressure (IOP) in his left eye was controlled without medications.This case highlights the rare association of aniridia with congenital aphakia and secondary glaucoma.

View Article: PubMed Central - PubMed

Affiliation: VST Center for Glaucoma Care, L.V. Prasad Eye Institute, Hyderabad, India.

ABSTRACT
We report a case of aniridia associated with congenital aphakia and secondary glaucoma. A 35-year-old male presented with aniridia, congenital aphakia and secondary glaucoma in both eyes. After an unsuccessful medical management, he underwent trabeculectomy with mitomycin C and anterior vitrectomy under local anesthesia in his left eye. Postoperatively, at the end of six months, intraocular pressure (IOP) in his left eye was controlled without medications. This case highlights the rare association of aniridia with congenital aphakia and secondary glaucoma.

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Left eye of the patient with aphakia and aniridia. The patient's left cornea has mild haze. Aniridia and aphakia can be noted
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Figure 0001: Left eye of the patient with aphakia and aniridia. The patient's left cornea has mild haze. Aniridia and aphakia can be noted

Mentions: A 35-year-old male presented with complaints of decreased vision in both eyes for 15 years. There was no history of intraocular surgery in either eye. His best-corrected visual acuity was no perception of light in the right eye and 20/400 in the left eye with + 9.0 diopter sphere (Dsph). Horizontal pendular nystagmus was noted in both eyes. Examination of the right eye revealed corneal stromal edema and an intercalary staphyloma. The cornea in the left eye had mild corneal haze. Both eyes had aniridia and were aphakic. The view in the left eye was clearer and showed aphakia with total absence of zonules [Fig. 1]. Intraocular pressure (IOP) measured by Goldmann applanation tonometry was 28 mm Hg and 36 mm Hg in the right and left eye respectively. Corneal edema obscured visualization of the angle in the right eye. Gonioscopy in the left eye with a four-mirror lens showed open angles up to the cilliary body inferiorly; the stump of the iris had formed peripheral anterior synechia (PAS) superiorly. Fundus details were not clear in the right eye but a total glaucomatous optic atrophy was noted. Fundus examination of the left eye showed a near total glaucomatous optic atrophy (vertical disc diameter of 2.1 mm, 0.9:1 cup disc ratio with bipolar notch) as well as foveal hypoplasia. As the IOP was uncontrolled with topical 0.5% timolol maleate eye drops and 0.15% brimonidine tartarate eye drops, the patient underwent trabeculectomy with Mitomycin C under local anesthesia in his left eye. Partial anterior vitrectomy was performed at the same time.


Aniridia associated with congenital aphakia and secondary glaucoma.

Moreker M, Parikh R, Parikh SR, Thomas R - Indian J Ophthalmol (2009 Jul-Aug)

Left eye of the patient with aphakia and aniridia. The patient's left cornea has mild haze. Aniridia and aphakia can be noted
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2712705&req=5

Figure 0001: Left eye of the patient with aphakia and aniridia. The patient's left cornea has mild haze. Aniridia and aphakia can be noted
Mentions: A 35-year-old male presented with complaints of decreased vision in both eyes for 15 years. There was no history of intraocular surgery in either eye. His best-corrected visual acuity was no perception of light in the right eye and 20/400 in the left eye with + 9.0 diopter sphere (Dsph). Horizontal pendular nystagmus was noted in both eyes. Examination of the right eye revealed corneal stromal edema and an intercalary staphyloma. The cornea in the left eye had mild corneal haze. Both eyes had aniridia and were aphakic. The view in the left eye was clearer and showed aphakia with total absence of zonules [Fig. 1]. Intraocular pressure (IOP) measured by Goldmann applanation tonometry was 28 mm Hg and 36 mm Hg in the right and left eye respectively. Corneal edema obscured visualization of the angle in the right eye. Gonioscopy in the left eye with a four-mirror lens showed open angles up to the cilliary body inferiorly; the stump of the iris had formed peripheral anterior synechia (PAS) superiorly. Fundus details were not clear in the right eye but a total glaucomatous optic atrophy was noted. Fundus examination of the left eye showed a near total glaucomatous optic atrophy (vertical disc diameter of 2.1 mm, 0.9:1 cup disc ratio with bipolar notch) as well as foveal hypoplasia. As the IOP was uncontrolled with topical 0.5% timolol maleate eye drops and 0.15% brimonidine tartarate eye drops, the patient underwent trabeculectomy with Mitomycin C under local anesthesia in his left eye. Partial anterior vitrectomy was performed at the same time.

Bottom Line: After an unsuccessful medical management, he underwent trabeculectomy with mitomycin C and anterior vitrectomy under local anesthesia in his left eye.Postoperatively, at the end of six months, intraocular pressure (IOP) in his left eye was controlled without medications.This case highlights the rare association of aniridia with congenital aphakia and secondary glaucoma.

View Article: PubMed Central - PubMed

Affiliation: VST Center for Glaucoma Care, L.V. Prasad Eye Institute, Hyderabad, India.

ABSTRACT
We report a case of aniridia associated with congenital aphakia and secondary glaucoma. A 35-year-old male presented with aniridia, congenital aphakia and secondary glaucoma in both eyes. After an unsuccessful medical management, he underwent trabeculectomy with mitomycin C and anterior vitrectomy under local anesthesia in his left eye. Postoperatively, at the end of six months, intraocular pressure (IOP) in his left eye was controlled without medications. This case highlights the rare association of aniridia with congenital aphakia and secondary glaucoma.

Show MeSH
Related in: MedlinePlus