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Non-O1 Vibrio cholerae inguinal skin and soft tissue infection with bullous skin lesions in a patient with a penis squamous cell carcinoma.

Aguinaga A, Portillo ME, Yuste JR, del Pozo JL, García-Tutor E, Pérez-Gracia JL, Leiva J - Ann. Clin. Microbiol. Antimicrob. (2009)

Bottom Line: Vibrio spp. is a pathogen rarely isolated in cancer patients, and in most cases it is associated with haematological diseases.Cutaneous manifestations of this organism are even rarer.We report a case of Non-O1 Vibrio cholerae inguinal skin and soft tissue infection presenting bullous skin lesions in a young type II diabetic patient with a penis squamous cell carcinoma having a seawater exposure history.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Clinical Microbiology, University Hospital of Navarra, Pamplona, Spain. aaguinaga@unav.es

ABSTRACT
Vibrio spp. is a pathogen rarely isolated in cancer patients, and in most cases it is associated with haematological diseases. Cutaneous manifestations of this organism are even rarer. We report a case of Non-O1 Vibrio cholerae inguinal skin and soft tissue infection presenting bullous skin lesions in a young type II diabetic patient with a penis squamous cell carcinoma having a seawater exposure history.

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Skin lesions and cellulitis after a mayor cure.
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Figure 2: Skin lesions and cellulitis after a mayor cure.

Mentions: The patient was treated with a left inguinal region debridement, percutaneous drainage and flamazine therapy. Purulent fluid was obtained by swabbing from the fistulized left bulla and was sent for culture (Figure 2). At that time, two sets of blood cultures were drawn. Empiric intravenous antimicrobial therapy with ceftriaxone 1 g/24 h and metronidazole 500 mg/8 h was started. Daily cures with Flamazine were also indicated. A Gram stain of the sample showed abundant polymorphonuclear leukocytes, and cultures yielded Escherichia coli, Serratia marcescens and V. cholerae susceptible to the empiric antimicrobial therapy instituted. Blood cultures were sterile after incubation for six days. As the patient was not improving after 7 days of therapy, a new sample was taken with a syringe. Methicillin-susceptible Staphylococcus aureus and the same E. coli, characterized by phenotypic methods (biotype and antimicrobial susceptibility) were isolated. Those microorganisms were carbapenems-susceptible so the antibiotic therapy was switched to ertapenem 1 g/24 h i.v. and cellulitis gradually improved.


Non-O1 Vibrio cholerae inguinal skin and soft tissue infection with bullous skin lesions in a patient with a penis squamous cell carcinoma.

Aguinaga A, Portillo ME, Yuste JR, del Pozo JL, García-Tutor E, Pérez-Gracia JL, Leiva J - Ann. Clin. Microbiol. Antimicrob. (2009)

Skin lesions and cellulitis after a mayor cure.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2691727&req=5

Figure 2: Skin lesions and cellulitis after a mayor cure.
Mentions: The patient was treated with a left inguinal region debridement, percutaneous drainage and flamazine therapy. Purulent fluid was obtained by swabbing from the fistulized left bulla and was sent for culture (Figure 2). At that time, two sets of blood cultures were drawn. Empiric intravenous antimicrobial therapy with ceftriaxone 1 g/24 h and metronidazole 500 mg/8 h was started. Daily cures with Flamazine were also indicated. A Gram stain of the sample showed abundant polymorphonuclear leukocytes, and cultures yielded Escherichia coli, Serratia marcescens and V. cholerae susceptible to the empiric antimicrobial therapy instituted. Blood cultures were sterile after incubation for six days. As the patient was not improving after 7 days of therapy, a new sample was taken with a syringe. Methicillin-susceptible Staphylococcus aureus and the same E. coli, characterized by phenotypic methods (biotype and antimicrobial susceptibility) were isolated. Those microorganisms were carbapenems-susceptible so the antibiotic therapy was switched to ertapenem 1 g/24 h i.v. and cellulitis gradually improved.

Bottom Line: Vibrio spp. is a pathogen rarely isolated in cancer patients, and in most cases it is associated with haematological diseases.Cutaneous manifestations of this organism are even rarer.We report a case of Non-O1 Vibrio cholerae inguinal skin and soft tissue infection presenting bullous skin lesions in a young type II diabetic patient with a penis squamous cell carcinoma having a seawater exposure history.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Clinical Microbiology, University Hospital of Navarra, Pamplona, Spain. aaguinaga@unav.es

ABSTRACT
Vibrio spp. is a pathogen rarely isolated in cancer patients, and in most cases it is associated with haematological diseases. Cutaneous manifestations of this organism are even rarer. We report a case of Non-O1 Vibrio cholerae inguinal skin and soft tissue infection presenting bullous skin lesions in a young type II diabetic patient with a penis squamous cell carcinoma having a seawater exposure history.

Show MeSH
Related in: MedlinePlus