Limits...
Ocular toxicity by latex of Calotropis procera (Sodom apple).

Basak SK, Bhaumik A, Mohanta A, Singhal P - Indian J Ophthalmol (2009 May-Jun)

Bottom Line: Three (10%) eyes had an epithelial defect, nine (31%) had iridocyclitis, and seven (24%) had associated secondary glaucoma.After three months, 17 (74%) out of 23 eyes showed a significant low endothelial cell count compared to the normal fellow eye ( P 0.001).The long-term effect on corneal endothelium has to be studied further.

View Article: PubMed Central - PubMed

Affiliation: Disha Eye Hospitals and Research Centre, Barrackpore, West Bengal, Kolkata - 700 120, India. basak_sk@hotmail.com

ABSTRACT
We report the spectrum of ocular toxicity following accidental inoculation of latex of Calotropis procera (Sodom apple) in 29 eyes between January 2003 and December 2006. All patients presented with sudden painless dimness of vision with photophobia. Twenty-five (86%) patients had initial visual acuity of less than 20/60. All eyes had conjunctival congestion and mild to severe corneal edema with Descemet's folds. Three (10%) eyes had an epithelial defect, nine (31%) had iridocyclitis, and seven (24%) had associated secondary glaucoma. After treatment with topical corticosteroids, antiglaucoma agents, cycloplegics, hypertonic saline and tears supplements, 27 (93%) eyes recovered completely within 3-14 days. After three months, 17 (74%) out of 23 eyes showed a significant low endothelial cell count compared to the normal fellow eye ( P 0.001). The latex of Calotropis procera causes significant ocular morbidity which may be preventable by simple health education. The long-term effect on corneal endothelium has to be studied further.

Show MeSH

Related in: MedlinePlus

Flower and leaves of Calotropis procera
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC2683444&req=5

Figure 0001: Flower and leaves of Calotropis procera

Mentions: Calotropis procera is a member of the milkweed or Asclepiadeae family and it is the scientific name of Sodom apple or Madar shrub. In India, it is found mainly in Assam, West Bengal, Rajasthan, Punjab, particularly in the wastelands.[1] They are medium-branched and perennial shrubs or small trees that grow up to a height of 4–5 meters with milky latex throughout. It has white or pink flowers which bloom between February and June [Fig. 1a].[2] In Bengali, it is known as Akanda and in Hindi as Ak. Its flower or garland and the leaves are used to worship Lord Shiva during the festive season in the months of February and April every year in West Bengal [Fig. 1b]. Thus, it is not so uncommon to get ocular injuries caused by accidental contact or inoculation of the latex of Calotropis procera during plucking of the flower or leaf stalk during this season.


Ocular toxicity by latex of Calotropis procera (Sodom apple).

Basak SK, Bhaumik A, Mohanta A, Singhal P - Indian J Ophthalmol (2009 May-Jun)

Flower and leaves of Calotropis procera
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2683444&req=5

Figure 0001: Flower and leaves of Calotropis procera
Mentions: Calotropis procera is a member of the milkweed or Asclepiadeae family and it is the scientific name of Sodom apple or Madar shrub. In India, it is found mainly in Assam, West Bengal, Rajasthan, Punjab, particularly in the wastelands.[1] They are medium-branched and perennial shrubs or small trees that grow up to a height of 4–5 meters with milky latex throughout. It has white or pink flowers which bloom between February and June [Fig. 1a].[2] In Bengali, it is known as Akanda and in Hindi as Ak. Its flower or garland and the leaves are used to worship Lord Shiva during the festive season in the months of February and April every year in West Bengal [Fig. 1b]. Thus, it is not so uncommon to get ocular injuries caused by accidental contact or inoculation of the latex of Calotropis procera during plucking of the flower or leaf stalk during this season.

Bottom Line: Three (10%) eyes had an epithelial defect, nine (31%) had iridocyclitis, and seven (24%) had associated secondary glaucoma.After three months, 17 (74%) out of 23 eyes showed a significant low endothelial cell count compared to the normal fellow eye ( P 0.001).The long-term effect on corneal endothelium has to be studied further.

View Article: PubMed Central - PubMed

Affiliation: Disha Eye Hospitals and Research Centre, Barrackpore, West Bengal, Kolkata - 700 120, India. basak_sk@hotmail.com

ABSTRACT
We report the spectrum of ocular toxicity following accidental inoculation of latex of Calotropis procera (Sodom apple) in 29 eyes between January 2003 and December 2006. All patients presented with sudden painless dimness of vision with photophobia. Twenty-five (86%) patients had initial visual acuity of less than 20/60. All eyes had conjunctival congestion and mild to severe corneal edema with Descemet's folds. Three (10%) eyes had an epithelial defect, nine (31%) had iridocyclitis, and seven (24%) had associated secondary glaucoma. After treatment with topical corticosteroids, antiglaucoma agents, cycloplegics, hypertonic saline and tears supplements, 27 (93%) eyes recovered completely within 3-14 days. After three months, 17 (74%) out of 23 eyes showed a significant low endothelial cell count compared to the normal fellow eye ( P 0.001). The latex of Calotropis procera causes significant ocular morbidity which may be preventable by simple health education. The long-term effect on corneal endothelium has to be studied further.

Show MeSH
Related in: MedlinePlus